[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr1:106,906,072-108,296,508

Best TWAS P=5.03e-08 · Best GWAS P=3.89e-09 conditioned to 2.16e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRMT6 0.19 0.16 lasso 6 0.16 5.4e-19 5.1 -5.2 2.6e-07 -0.08 0.22 0.78 FALSE
2 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 5.0 -5.2 1.7e-07 -0.09 0.25 0.75 FALSE
3 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 5.0 -5.3 1.4e-07 -0.08 0.23 0.77 FALSE
4 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 5.1 -5.5 5.0e-08 -0.08 0.23 0.77 TRUE
5 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 5.1 -5.3 1.1e-07 -0.08 0.23 0.77 FALSE
6 METSIM Adipose PRMT6 0.21 0.20 lasso 9 0.21 1.1e-30 5.1 -5.1 2.9e-07 -0.08 0.24 0.75 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 5.1 -5.2 2.1e-07 -0.09 0.01 0.99 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 5.0 -5.2 2.0e-07 -0.09 0.01 0.99 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 5.1 -5.2 2.4e-07 -0.09 0.01 0.99 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 5.1 -5.3 1.0e-07 -0.09 0.01 0.99 FALSE