Best TWAS P=6.29e-09 · Best GWAS P=1.05e-06 conditioned to 0.252
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | SYPL2 | 0.34 | 0.27 | lasso | 5 | 0.30 | 4.6e-09 | 4.5 | 5.3 | 8.6e-08 | 0.59 | 0.04 | 0.94 | FALSE |
| 2 | GTEx | Liver | ATXN7L2 | 0.39 | 0.04 | lasso | 12 | 0.21 | 1.3e-06 | 4.8 | 5.8 | 6.3e-09 | 0.70 | 0.04 | 0.86 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SYPL2 | 0.07 | 0.04 | blup | 45 | 0.03 | 4.9e-04 | 4.5 | -5.2 | 2.2e-07 | -0.51 | 0.02 | 0.94 | FALSE |