Best TWAS P=2.06e-22 · Best GWAS P=6.58e-32 conditioned to 0.000215
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | CERS5 | 0.09 | 0.03 | lasso | 3 | 0.05 | 0.01750 | 1.03 | -7.6 | 3.7e-14 | -0.53 | 0.05 | 0.22 | FALSE |
| 2 | GTEx | Testis | FAIM2 | 0.27 | 0.09 | lasso | 5 | 0.06 | 0.00093 | 10.28 | -9.7 | 2.1e-22 | -0.77 | 0.05 | 0.84 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAIM2 | 0.02 | 0.00 | blup | 71 | 0.01 | 0.00853 | 0.24 | -6.4 | 1.6e-10 | -0.36 | 0.16 | 0.12 | TRUE |