[Hub]/) : Traits : Leg predicted mass (right) :

chr13:49,409,343-52,109,040

Best TWAS P=2.26e-25 · Best GWAS P=1.6e-58 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLEU7 0.05 0.00 blup 581 0.02 1.6e-03 1.23 6.8 1.2e-11 -0.46 0.08 0.21 TRUE
2 CommonMind Brain Pre-frontal Cortex EBPL 0.34 0.16 bslmm 399 0.33 2.5e-41 0.10 -5.6 2.1e-08 0.04 1.00 0.00 TRUE
3 GTEx Artery Aorta EBPL 0.43 0.20 enet 78 0.28 8.1e-16 6.44 -5.9 4.9e-09 0.14 1.00 0.00 FALSE
4 GTEx Brain Caudate basal ganglia EBPL 0.41 0.06 lasso 7 0.12 2.1e-04 6.33 -5.5 3.5e-08 0.02 0.11 0.17 FALSE
5 GTEx Brain Cerebellum EBPL 0.50 0.30 enet 23 0.36 1.8e-11 7.37 -6.5 9.8e-11 0.05 0.86 0.01 FALSE
6 GTEx Brain Cortex EBPL 0.36 0.08 enet 24 0.14 1.5e-04 7.37 -5.6 2.5e-08 0.14 0.18 0.15 TRUE
7 GTEx Brain Nucleus accumbens basal ganglia EBPL 0.25 0.11 enet 21 0.11 7.9e-04 6.46 -5.6 2.6e-08 0.12 0.13 0.09 FALSE
8 GTEx Brain Putamen basal ganglia EBPL 0.31 -0.01 enet 18 0.05 2.9e-02 6.46 -5.4 6.3e-08 0.08 0.06 0.13 FALSE
9 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 6.33 -6.4 1.2e-10 0.02 1.00 0.00 FALSE
10 GTEx Esophagus Muscularis EBPL 0.39 0.16 enet 36 0.29 9.2e-18 6.44 -5.8 8.2e-09 0.03 1.00 0.00 FALSE
11 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 7.27 7.5 4.5e-14 -0.11 0.51 0.02 TRUE
12 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 7.37 -6.2 5.1e-10 0.07 0.38 0.04 TRUE
13 GTEx Pituitary EBPL 0.44 0.32 enet 29 0.37 3.1e-10 6.44 -6.0 2.3e-09 -0.02 0.92 0.01 TRUE
14 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 6.44 -6.1 9.6e-10 0.00 1.00 0.00 FALSE
15 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 6.76 -6.9 6.5e-12 0.02 1.00 0.00 FALSE
16 GTEx Spleen RCBTB1 0.37 0.02 lasso 5 0.04 3.5e-02 -0.24 -5.5 3.4e-08 0.01 0.04 0.10 FALSE
17 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 6.48 -7.3 2.5e-13 0.03 1.00 0.00 FALSE
18 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 6.33 -6.0 2.1e-09 0.08 1.00 0.00 TRUE
19 METSIM Adipose EBPL 0.32 0.12 lasso 7 0.27 1.4e-39 6.48 -5.2 2.4e-07 0.03 1.00 0.00 FALSE
20 NTR Blood DLEU7 0.07 0.02 enet 22 0.06 1.3e-19 -6.52 -10.4 2.3e-25 0.61 0.11 0.89 TRUE
21 ROSMAP Brain Pre-frontal Cortex EBPL 0.43 0.28 lasso 8 0.43 7.3e-60 6.33 -5.6 2.7e-08 0.03 1.00 0.00 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DLEU2 0.08 0.02 lasso 2 0.01 1.6e-02 -4.99 5.3 1.5e-07 0.02 0.14 0.20 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EBPL 0.27 0.16 blup 59 0.22 1.0e-12 -0.94 -5.4 8.4e-08 0.06 0.29 0.71 TRUE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 7.18 6.9 4.2e-12 -0.10 0.01 0.95 FALSE
25 The Cancer Genome Atlas Pancreatic Adenocarcinoma EBPL 0.21 0.09 enet 10 0.13 4.9e-06 7.37 -6.0 1.6e-09 0.07 0.00 1.00 FALSE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 6.46 -6.0 2.0e-09 0.06 0.01 0.98 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma EBPL 0.08 0.01 blup 59 0.04 6.4e-05 6.46 -5.4 5.9e-08 0.04 0.01 0.89 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma EBPL 0.28 0.10 enet 17 0.26 7.7e-25 -0.94 -5.2 1.9e-07 0.02 0.24 0.76 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma TRIM13 0.04 0.00 blup 26 0.02 8.5e-03 7.30 -7.1 1.2e-12 0.06 0.00 0.46 FALSE