Best TWAS P=8.15e-09 · Best GWAS P=3.59e-10 conditioned to 0.0108
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | RP4-773A18.4 | 0.10 | 0.03 | enet | 16 | 0.04 | 2.6e-04 | 6.27 | -5.8 | 8.2e-09 | -0.87 | 0.00 | 1.00 | TRUE |
2 | GTEx | Thyroid | RP4-773A18.4 | 0.17 | 0.03 | lasso | 6 | 0.11 | 5.8e-09 | 4.51 | -5.5 | 2.9e-08 | -0.70 | 0.03 | 0.97 | FALSE |
3 | METSIM | Adipose | RP5-836N10.1 | 0.04 | 0.00 | bslmm | 695 | 0.01 | 1.7e-02 | 0.23 | 5.1 | 3.0e-07 | 0.64 | 0.01 | 0.98 | FALSE |