[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr2:85,083,503-86,513,102

Best TWAS P=8.7e-10 · Best GWAS P=2.71e-09 conditioned to 0.0284

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta GGCX 0.23 0.22 lasso 6 0.23 5.5e-13 4.7 5.3 1.4e-07 0.74 0.51 0.49 FALSE
2 GTEx Artery Tibial GGCX 0.29 0.22 enet 14 0.24 6.3e-19 4.7 5.5 3.2e-08 0.69 0.59 0.40 FALSE
3 GTEx Brain Cerebellum GGCX 0.54 0.30 lasso 10 0.34 6.0e-11 4.7 5.3 1.2e-07 0.75 0.61 0.38 FALSE
4 GTEx Colon Transverse GGCX 0.26 0.28 lasso 3 0.28 1.4e-13 4.7 5.2 2.4e-07 0.73 0.54 0.45 FALSE
5 GTEx Esophagus Muscularis GGCX 0.14 0.12 lasso 9 0.12 1.1e-07 4.7 5.3 1.1e-07 0.75 0.42 0.58 FALSE
6 GTEx Muscle Skeletal GGCX 0.10 0.04 enet 11 0.02 2.7e-03 4.7 5.5 4.2e-08 0.78 0.09 0.91 FALSE
7 GTEx Nerve Tibial GGCX 0.38 0.30 lasso 7 0.33 6.5e-24 4.7 5.5 3.7e-08 0.72 0.60 0.40 FALSE
8 GTEx Pancreas VAMP5 0.29 0.09 enet 4 0.05 3.2e-03 5.2 -5.7 1.0e-08 -0.66 0.02 0.76 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic GGCX 0.13 0.04 enet 11 0.06 3.9e-04 4.7 5.4 5.8e-08 0.64 0.25 0.37 FALSE
10 GTEx Skin Sun Exposed Lower leg GGCX 0.15 0.11 lasso 3 0.18 7.9e-15 4.7 5.8 7.6e-09 0.69 0.42 0.58 FALSE
11 GTEx Testis GGCX 0.38 0.36 enet 25 0.40 8.6e-19 4.7 5.3 1.0e-07 0.72 0.53 0.47 FALSE
12 GTEx Thyroid GGCX 0.30 0.17 enet 10 0.23 1.4e-17 4.7 5.5 3.1e-08 0.74 0.56 0.44 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma C2orf68 0.06 0.06 lasso 2 0.05 1.1e-03 5.2 -5.1 2.8e-07 -0.88 0.02 0.70 FALSE
14 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma VAMP8 0.06 0.01 enet 15 0.02 2.1e-02 5.1 5.3 1.3e-07 0.45 0.04 0.21 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma GGCX 0.04 0.02 blup 44 0.02 2.7e-03 5.0 6.1 8.7e-10 0.72 0.10 0.71 TRUE