Best TWAS P=6.6e-09 · Best GWAS P=5.54e-10 conditioned to 0.0192
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-10C24.2 | 0.11 | 0.06 | lasso | 3 | 0.05 | 8.9e-05 | 6.0 | 5.6 | 2.2e-08 | 0.87 | 0.01 | 0.99 | TRUE |
| 2 | YFS | Blood | GLB1 | 0.05 | 0.01 | enet | 9 | 0.02 | 5.2e-06 | 4.9 | 5.8 | 6.6e-09 | 0.03 | 0.75 | 0.12 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GLB1 | 0.05 | 0.03 | blup | 83 | 0.03 | 2.3e-04 | -4.0 | 5.2 | 1.8e-07 | 0.00 | 0.19 | 0.30 | FALSE |