Best TWAS P=1.15e-10 · Best GWAS P=9.36e-12 conditioned to 0.00551
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.2 | -6.2 | 5.1e-10 | -0.70 | 0.04 | 0.26 | FALSE |
| 2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 6.3 | 6.4 | 1.2e-10 | 0.80 | 0.07 | 0.55 | TRUE |
| 3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 6.2 | -6.4 | 1.4e-10 | -0.75 | 0.22 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ULK4 | 0.12 | 0.03 | blup | 256 | 0.05 | 1.9e-03 | 2.9 | 5.4 | 7.1e-08 | 0.35 | 0.24 | 0.07 | FALSE |