[Hub]/) : Traits : Leg predicted mass (right) :

chr4:16,922,182-18,507,692

Best TWAS P=1.76e-41 · Best GWAS P=1.66e-37 conditioned to 0.0013

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 7.5 7.2 6.7e-13 -0.24 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 7.5 8.4 3.1e-17 -0.35 0.30 0.45 FALSE
3 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -12.0 13.5 1.8e-41 -0.81 0.06 0.77 TRUE
4 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 8.8 9.8 7.1e-23 -0.36 1.00 0.00 FALSE
5 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 7.6 10.0 2.2e-23 -0.52 0.14 0.67 FALSE
6 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -11.4 11.1 2.0e-28 -0.76 0.04 0.60 FALSE
7 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 7.5 7.5 7.2e-14 -0.27 0.06 0.09 FALSE
8 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 7.6 7.9 2.2e-15 -0.37 0.13 0.40 FALSE
9 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 7.5 7.2 4.1e-13 -0.27 0.99 0.00 FALSE
10 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 7.5 8.5 1.4e-17 -0.37 0.99 0.01 FALSE
11 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 7.5 7.7 1.0e-14 -0.38 0.07 0.32 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 8.4 9.2 2.6e-20 -0.35 0.64 0.04 FALSE
13 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 7.6 8.4 3.9e-17 -0.28 1.00 0.00 FALSE
14 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 7.5 11.9 2.1e-32 -0.66 0.05 0.57 FALSE
15 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 8.7 9.6 7.5e-22 -0.26 0.19 0.05 FALSE
16 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 7.5 11.1 2.2e-28 -0.54 0.18 0.69 FALSE
17 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -4.3 -5.8 7.5e-09 0.26 1.00 0.00 FALSE
18 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -4.2 5.5 4.2e-08 -0.30 0.22 0.03 FALSE
19 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -11.5 11.1 1.2e-28 -0.83 0.03 0.89 FALSE
20 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 8.8 8.8 1.0e-18 -0.25 0.84 0.04 FALSE
21 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -11.6 -10.3 1.1e-24 0.84 0.01 0.98 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -11.5 -11.2 3.7e-29 0.84 0.39 0.61 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 8.8 12.5 4.2e-36 -0.64 0.09 0.77 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -11.6 -11.6 2.9e-31 0.88 0.02 0.61 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -11.6 -7.4 1.5e-13 0.68 0.03 0.79 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 7.5 11.1 1.3e-28 -0.58 0.28 0.21 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -10.5 -9.6 8.1e-22 0.76 0.02 0.72 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 8.7 12.0 2.4e-33 -0.65 0.14 0.79 FALSE