[Hub]/) : Traits : Leg predicted mass (right) :

chr5:36,410,564-38,450,430

Best TWAS P=3.79e-16 · Best GWAS P=1.07e-19 conditioned to 5.5e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C5orf42 0.04 0.03 lasso 4 0.04 1.2e-05 -6.8 6.3 3.4e-10 -0.65 0.40 0.48 FALSE
2 GTEx Cells Transformed fibroblasts WDR70 0.06 0.03 lasso 8 0.03 3.5e-03 -7.1 7.7 1.3e-14 -0.72 0.38 0.43 FALSE
3 GTEx Nerve Tibial WDR70 0.17 0.07 lasso 3 0.05 1.4e-04 7.3 7.0 2.1e-12 -0.43 0.39 0.04 FALSE
4 GTEx Whole Blood NUP155 0.05 0.01 enet 14 0.04 1.1e-04 -9.1 6.5 1.1e-10 -0.61 0.00 0.95 FALSE
5 GTEx Whole Blood C5orf42 0.07 0.00 enet 16 0.01 1.8e-02 -9.1 7.2 7.1e-13 -0.68 0.01 0.88 FALSE
6 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C5orf42 0.04 0.05 lasso 3 0.04 1.1e-03 -8.4 8.2 3.8e-16 -0.92 0.00 0.95 TRUE