Best TWAS P=2.83e-09 · Best GWAS P=3.78e-10 conditioned to 0.161
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | GALNT16 | 0.26 | 0.04 | lasso | 7 | 0.04 | 0.033 | 6.3 | 5.6 | 2.1e-08 | 0.84 | 0.02 | 0.86 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | EXD2 | 0.03 | 0.00 | blup | 52 | 0.01 | 0.015 | 6.0 | -5.9 | 2.8e-09 | -0.60 | 0.01 | 0.73 | TRUE |