[Hub]/) : Traits : Leg fat percentage (left) : ← →

chr18:12,090,696-13,822,256

Best TWAS P=2.55e-09 · Best GWAS P=5.28e-09 conditioned to 0.0229

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CEP192 0.38 0.35 lasso 4 0.43 3.0e-24 -4.5 -5.4 7.5e-08 -0.66 0.80 0.19 FALSE
2 GTEx Brain Cortex CEP192 0.40 0.26 lasso 6 0.26 9.9e-08 -4.5 -5.1 2.9e-07 -0.67 0.60 0.37 FALSE
3 GTEx Brain Hippocampus CEP192 0.43 0.35 lasso 9 0.44 9.8e-12 -4.5 -5.6 1.6e-08 -0.76 0.26 0.73 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia PTPN2 0.32 0.02 lasso 10 0.05 2.2e-02 5.5 6.0 2.6e-09 0.71 0.06 0.43 TRUE
5 GTEx Colon Sigmoid CEP192 0.33 0.32 enet 23 0.32 3.6e-12 -4.5 -5.1 2.9e-07 -0.69 0.79 0.20 FALSE
6 GTEx Liver CEP192 0.41 0.29 lasso 6 0.41 1.6e-12 -4.5 -5.1 2.6e-07 -0.72 0.64 0.36 FALSE
7 GTEx Pituitary CEP192 0.51 0.24 enet 29 0.39 1.0e-10 -4.4 -5.5 3.3e-08 -0.79 0.08 0.91 FALSE
8 ROSMAP Brain Pre-frontal Cortex SEH1L 0.04 0.05 lasso 1 0.03 2.6e-05 5.2 -5.2 2.5e-07 -0.84 0.13 0.83 FALSE
9 ROSMAP Brain Pre-frontal Cortex CEP192 0.30 0.42 enet 46 0.45 4.1e-64 -4.5 -5.4 5.9e-08 -0.74 0.79 0.20 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma CEP192 0.09 0.14 blup 85 0.14 8.4e-16 -4.5 -5.2 1.6e-07 -0.72 0.82 0.17 FALSE