[Hub]/) : Traits : Leg fat percentage (left) : ← →

chr18:12,090,696-13,822,256

Best TWAS P=2.55e-09 · Best GWAS P=5.28e-09 conditioned to 0.0229

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Nucleus accumbens basal ganglia	PTPN2	0.32	0.02	lasso	10	0.05	2.2e-02	5.5	6.0	2.6e-09	0.71	0.06	0.43	TRUE
3	GTEx	Brain Hippocampus	CEP192	0.43	0.35	lasso	9	0.44	9.8e-12	-4.5	-5.6	1.6e-08	-0.76	0.26	0.73	FALSE
7	GTEx	Pituitary	CEP192	0.51	0.24	enet	29	0.39	1.0e-10	-4.4	-5.5	3.3e-08	-0.79	0.08	0.91	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	CEP192	0.30	0.42	enet	46	0.45	4.1e-64	-4.5	-5.4	5.9e-08	-0.74	0.79	0.20	FALSE
1	GTEx	Adipose Visceral Omentum	CEP192	0.38	0.35	lasso	4	0.43	3.0e-24	-4.5	-5.4	7.5e-08	-0.66	0.80	0.19	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	CEP192	0.09	0.14	blup	85	0.14	8.4e-16	-4.5	-5.2	1.6e-07	-0.72	0.82	0.17	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	SEH1L	0.04	0.05	lasso	1	0.03	2.6e-05	5.2	-5.2	2.5e-07	-0.84	0.13	0.83	FALSE
6	GTEx	Liver	CEP192	0.41	0.29	lasso	6	0.41	1.6e-12	-4.5	-5.1	2.6e-07	-0.72	0.64	0.36	FALSE
2	GTEx	Brain Cortex	CEP192	0.40	0.26	lasso	6	0.26	9.9e-08	-4.5	-5.1	2.9e-07	-0.67	0.60	0.37	FALSE
5	GTEx	Colon Sigmoid	CEP192	0.33	0.32	enet	23	0.32	3.6e-12	-4.5	-5.1	2.9e-07	-0.69	0.79	0.20	FALSE