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Traits
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Leg fat percentage (left)
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chr19:3,309,021-5,052,147
Best TWAS P=5.77e-14 · Best GWAS P=6.08e-18 conditioned to 0.000503
3.4M
3.6M
3.8M
4M
4.2M
4.4M
4.6M
4.8M
5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Sigmoid
MAP2K2
0.20
0.11
lasso
3
0.13
3.0e-05
-6.9
-7.5
5.8e-14
0.64
0.02
0.84
TRUE
5
YFS
Blood
PIAS4
0.06
0.02
bslmm
369
0.04
4.8e-14
-6.7
-7.4
1.3e-13
0.60
0.03
0.97
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
PIAS4
0.14
0.12
lasso
6
0.11
1.6e-13
-6.7
-6.7
2.3e-11
0.58
1.00
0.00
FALSE
4
YFS
Blood
MAP2K2
0.02
0.00
blup
373
0.01
5.9e-03
3.0
6.0
2.6e-09
-0.51
0.09
0.46
FALSE
2
GTEx
Heart Left Ventricle
AC007292.4
0.18
0.00
enet
32
0.03
7.0e-03
-1.3
5.5
3.1e-08
-0.35
0.05
0.40
FALSE