Best TWAS P=1.26e-11 · Best GWAS P=1.25e-11 conditioned to 0.0289
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PEPD | 0.37 | 0.32 | enet | 20 | 0.39 | 9.5e-28 | 4.5 | 5.6 | 2.1e-08 | 0.73 | 0.04 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PEPD | 0.06 | 0.01 | blup | 114 | 0.04 | 2.6e-04 | 6.7 | 5.9 | 3.5e-09 | 0.85 | 0.01 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PEPD | 0.13 | 0.06 | blup | 113 | 0.10 | 1.2e-06 | 4.2 | 6.8 | 1.3e-11 | 0.81 | 0.03 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PEPD | 0.16 | 0.07 | lasso | 3 | 0.05 | 3.1e-03 | 6.7 | 6.4 | 1.3e-10 | 0.82 | 0.02 | 0.93 | FALSE |