Best TWAS P=1.79e-07 · Best GWAS P=2.94e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | GRIK5 | 0.41 | 0.24 | lasso | 10 | 0.24 | 7.9e-11 | 5.1 | -5.2 | 1.8e-07 | -0.96 | 0.01 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | GSK3A | 0.15 | 0.10 | lasso | 7 | 0.09 | 4.0e-03 | 5.1 | 5.1 | 3.0e-07 | 0.89 | 0.00 | 0.45 | FALSE |