Best TWAS P=2.6e-08 · Best GWAS P=1.21e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | WNT2B | 0.29 | 0.28 | lasso | 3 | 0.29 | 2.6e-08 | -5.0 | -5.4 | 8.7e-08 | 0.94 | 0.01 | 0.98 | FALSE |
2 | GTEx | Pituitary | ST7L | 0.31 | 0.18 | lasso | 7 | 0.18 | 3.0e-05 | -4.9 | -5.2 | 1.8e-07 | 0.89 | 0.01 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | MOV10 | 0.06 | 0.06 | lasso | 7 | 0.05 | 9.4e-06 | -5.7 | -5.6 | 2.6e-08 | 0.97 | 0.00 | 0.99 | TRUE |