Best TWAS P=7.67e-12 · Best GWAS P=6.66e-08 conditioned to 0.0699
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC26A1 | 0.12 | 0.06 | bslmm | 400 | 0.08 | 8.0e-10 | 4.7 | 5.9 | 4.3e-09 | 0.51 | 0.04 | 0.95 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | RP11-440L14.1 | 0.58 | 0.38 | enet | 36 | 0.48 | 1.9e-43 | -2.8 | 5.2 | 1.7e-07 | 0.16 | 0.77 | 0.01 | FALSE |
| 3 | GTEx | Brain Cerebellum | SLC26A1 | 0.61 | 0.41 | enet | 22 | 0.46 | 2.1e-15 | 4.7 | 5.4 | 5.6e-08 | 0.57 | 0.04 | 0.96 | FALSE |
| 4 | GTEx | Pituitary | SLC26A1 | 0.37 | 0.38 | enet | 14 | 0.33 | 3.9e-09 | 4.8 | 5.3 | 9.2e-08 | 0.65 | 0.03 | 0.96 | FALSE |
| 5 | GTEx | Stomach | SLC26A1 | 0.26 | 0.17 | enet | 14 | 0.16 | 4.0e-08 | 4.7 | 6.0 | 1.8e-09 | 0.63 | 0.03 | 0.96 | FALSE |
| 6 | NTR | Blood | PCGF3 | 0.07 | 0.00 | enet | 33 | 0.02 | 7.7e-08 | 4.4 | 5.4 | 6.1e-08 | 0.27 | 0.12 | 0.82 | FALSE |
| 7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PCGF3 | 0.03 | 0.00 | blup | 69 | 0.01 | 3.7e-03 | 4.4 | 6.8 | 7.7e-12 | 0.34 | 0.01 | 0.32 | TRUE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PCGF3 | 0.08 | 0.02 | lasso | 4 | 0.07 | 1.9e-08 | -4.3 | 5.3 | 1.1e-07 | 0.14 | 0.03 | 0.71 | FALSE |
| 9 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PCGF3 | 0.13 | 0.00 | blup | 69 | 0.04 | 1.4e-02 | -4.8 | 5.4 | 5.9e-08 | 0.10 | 0.01 | 0.57 | FALSE |