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Traits
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Traits
:
Leg fat percentage (left)
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chr4:55,582,068-56,988,744
Best TWAS P=2.09e-07 · Best GWAS P=5.35e-09 conditioned to 0.00147
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
57M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
TMEM165
0.09
0.07
blup
404
0.08
4.9e-11
4.5
-5.2
2.1e-07
-0.67
0.74
0.25
TRUE
1
GTEx
Adipose Subcutaneous
TMEM165
0.09
0.01
lasso
3
0.03
1.6e-03
4.8
-5.1
2.8e-07
-0.76
0.47
0.48
FALSE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SRD5A3
0.03
0.03
enet
4
0.05
3.1e-06
-5.3
5.1
2.9e-07
0.80
0.02
0.96
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
TMEM165
0.02
0.04
lasso
3
0.03
1.0e-07
4.8
-5.1
3.0e-07
-0.77
0.17
0.83
FALSE