[Hub]/) : Traits : Leg fat percentage (left) :

chr4:17,104,059-18,507,692

Best TWAS P=9.01e-12 · Best GWAS P=5.39e-13 conditioned to 0.000561

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 5.3 -6.2 5.7e-10 -0.69 0.16 0.32 FALSE
2 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 -4.6 -5.4 5.8e-08 -0.45 0.20 0.52 FALSE
3 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 5.9 -6.8 9.0e-12 -0.69 0.04 0.56 TRUE
4 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 -4.6 -5.3 9.2e-08 -0.32 0.16 0.28 FALSE
5 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 -4.5 -6.6 3.1e-11 -0.66 0.08 0.30 FALSE
6 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 -4.5 -6.1 1.3e-09 -0.53 0.31 0.46 FALSE
7 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 5.8 -5.5 4.3e-08 -0.79 0.03 0.90 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 5.8 5.6 1.7e-08 0.73 0.88 0.12 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 -4.5 -6.4 1.7e-10 -0.55 0.23 0.42 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 5.6 5.6 2.4e-08 0.75 0.03 0.53 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 -4.5 -6.4 1.9e-10 -0.60 0.21 0.41 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 6.3 5.9 3.5e-09 0.86 0.01 0.86 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 -4.7 -6.2 7.2e-10 -0.55 0.44 0.33 FALSE