Best TWAS P=6.29e-09 · Best GWAS P=9.25e-09 conditioned to 0.191
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | RANBP17 | 0.20 | 0.04 | lasso | 5 | 0.05 | 0.01620 | -4.9 | 5.2 | 2.3e-07 | -0.89 | 0.06 | 0.79 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RANBP17 | 0.02 | 0.00 | blup | 135 | 0.01 | 0.00037 | -5.6 | 5.8 | 6.3e-09 | -0.88 | 0.02 | 0.91 | TRUE |