Best TWAS P=7.38e-09 · Best GWAS P=6.29e-07 conditioned to 0.0126
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Putamen basal ganglia | TXNDC15 | 0.39 | -0.01 | enet | 22 | 0.06 | 1.6e-02 | -2.2 | 5.4 | 5.3e-08 | -0.20 | 0.02 | 0.07 | TRUE |
2 | METSIM | Adipose | SAR1B | 0.06 | 0.02 | bslmm | 288 | 0.03 | 3.1e-05 | 2.9 | 5.8 | 7.4e-09 | -0.48 | 0.12 | 0.50 | TRUE |