Best TWAS P=1.88e-10 · Best GWAS P=1.87e-11 conditioned to 0.0146
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | -6.2 | 6.4 | 1.9e-10 | 0.86 | 0.11 | 0.89 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | -5.9 | 5.4 | 5.9e-08 | 0.81 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | -6.0 | 5.4 | 6.0e-08 | 0.83 | 0.02 | 0.98 | FALSE |