Best TWAS P=7.07e-08 · Best GWAS P=5.6e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | FAM160B2 | 0.18 | 0.09 | lasso | 5 | 0.10 | 4.0e-08 | -5.4 | 5.2 | 2.2e-07 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | AC091171.1 | 0.15 | 0.06 | lasso | 2 | 0.05 | 2.2e-04 | -5.4 | 5.4 | 7.1e-08 | -1.00 | 0.00 | 0.99 | TRUE |
| 3 | GTEx | Esophagus Mucosa | AC091171.1 | 0.14 | 0.07 | lasso | 4 | 0.05 | 2.2e-04 | 5.0 | 5.1 | 3.0e-07 | -0.71 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | NUDT18 | 0.09 | 0.03 | blup | 45 | 0.08 | 1.3e-04 | -5.0 | -5.3 | 1.1e-07 | 0.90 | 0.02 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NUDT18 | 0.11 | 0.22 | lasso | 6 | 0.22 | 3.6e-24 | -5.4 | -5.3 | 1.0e-07 | 0.96 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | FAM160B2 | 0.08 | 0.06 | lasso | 4 | 0.05 | 1.4e-05 | -5.4 | 5.3 | 1.1e-07 | -0.93 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NUDT18 | 0.15 | 0.17 | lasso | 4 | 0.12 | 2.3e-04 | -5.3 | -5.3 | 9.7e-08 | 0.94 | 0.01 | 0.97 | FALSE |