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Traits
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Leg fat mass (left)
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chr12:55,694,116-57,125,879
Best TWAS P=4.1e-09 · Best GWAS P=3.68e-10 conditioned to 0.000164
55.8M
56M
56.2M
56.4M
56.6M
56.8M
57M
57.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Breast Mammary Tissue (Female)
RPS26
0.20
0.11
lasso
3
0.10
6.6e-04
-4.1
-5.9
4.1e-09
0.52
0.05
0.23
TRUE
1
GTEx
Breast Mammary Tissue
RPS26
0.29
0.05
enet
37
0.12
9.4e-07
-4.2
-5.7
1.2e-08
0.52
0.85
0.13
FALSE
3
GTEx
Prostate
SUOX
0.22
0.04
enet
11
0.05
2.3e-02
-4.1
5.6
2.1e-08
-0.77
0.02
0.86
FALSE