[Hub]/) : Traits : Leg fat mass (left) : ← →

chr12:89,116,708-90,682,621

Best TWAS P=1.65e-12 · Best GWAS P=2.39e-13 conditioned to 1.42e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	POC1B	0.13	0.06	enet	29	0.06	1.7e-05	6.0	-7.1	1.7e-12	-0.42	0.41	0.42	TRUE
1	GTEx	Adipose Subcutaneous	POC1B	0.12	0.08	lasso	9	0.09	1.7e-07	5.9	-6.3	2.8e-10	-0.37	0.94	0.04	FALSE
9	GTEx	Spleen	RP11-981P6.1	0.28	0.18	lasso	13	0.14	2.1e-04	5.4	6.0	1.5e-09	0.35	0.36	0.17	FALSE
10	GTEx	Thyroid	RP11-981P6.1	0.24	0.25	lasso	5	0.26	3.9e-20	6.0	6.0	2.5e-09	0.35	0.96	0.04	FALSE
7	GTEx	Esophagus Muscularis	RP11-981P6.1	0.18	0.10	lasso	3	0.06	2.9e-04	6.0	5.9	3.9e-09	0.32	0.84	0.09	FALSE
2	GTEx	Adrenal Gland	RP11-981P6.1	0.33	0.29	lasso	3	0.19	2.2e-07	5.9	5.8	7.4e-09	0.30	0.96	0.04	FALSE
6	GTEx	Colon Transverse	RP11-981P6.1	0.14	0.05	enet	26	0.05	1.9e-03	6.0	5.7	1.3e-08	0.28	0.32	0.24	FALSE
5	GTEx	Colon Sigmoid	RP11-981P6.1	0.19	0.12	lasso	4	0.11	9.7e-05	5.9	5.6	2.1e-08	0.32	0.32	0.07	FALSE
8	GTEx	Nerve Tibial	POC1B	0.30	0.18	lasso	6	0.22	1.0e-15	-3.6	-5.5	4.3e-08	-0.30	1.00	0.00	FALSE
4	GTEx	Artery Tibial	RP11-981P6.1	0.07	0.06	lasso	1	0.03	1.3e-03	5.4	5.4	6.4e-08	0.34	0.45	0.28	FALSE