[Hub]/) : Traits : Leg fat mass (left) :

chr1:106,906,072-108,296,508

Best TWAS P=1.11e-10 · Best GWAS P=5.87e-10 conditioned to 0.672

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRMT6 0.19 0.16 lasso 6 0.16 5.4e-19 6.2 -6.2 5.7e-10 -0.99 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous PRMT6 0.17 0.10 enet 6 0.11 5.1e-09 5.7 -6.1 8.9e-10 -0.95 0.01 0.99 FALSE
3 GTEx Adrenal Gland PRMT6 0.58 0.28 lasso 6 0.33 1.3e-12 5.9 -5.6 2.4e-08 -0.91 0.01 0.99 FALSE
4 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 6.0 -6.2 5.2e-10 -0.96 0.01 0.99 FALSE
5 GTEx Esophagus Mucosa PRMT6 0.33 0.23 lasso 7 0.29 1.4e-19 6.1 -6.2 7.2e-10 -0.97 0.01 0.99 FALSE
6 GTEx Heart Left Ventricle PRMT6 0.16 0.12 enet 9 0.13 2.3e-07 5.9 -6.1 1.1e-09 -0.88 0.01 0.99 FALSE
7 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 6.0 -6.4 2.0e-10 -0.99 0.01 0.99 FALSE
8 GTEx Lung PRMT6 0.11 0.14 lasso 2 0.13 2.2e-10 6.1 -6.1 1.1e-09 -0.96 0.01 0.99 FALSE
9 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 6.1 -6.5 1.1e-10 -0.94 0.01 0.99 TRUE
10 GTEx Skin Not Sun Exposed Suprapubic PRMT6 0.46 0.35 lasso 6 0.37 2.1e-21 6.1 -6.1 1.1e-09 -0.96 0.01 0.99 FALSE
11 GTEx Skin Sun Exposed Lower leg PRMT6 0.40 0.36 lasso 4 0.37 6.1e-32 6.1 -6.1 1.1e-09 -0.97 0.01 0.99 FALSE
12 GTEx Stomach PRMT6 0.29 0.16 enet 7 0.15 8.6e-08 6.2 -6.0 2.1e-09 -0.97 0.01 0.99 FALSE
13 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 6.1 -6.4 1.3e-10 -0.97 0.01 0.99 FALSE
14 METSIM Adipose PRMT6 0.21 0.20 lasso 9 0.21 1.1e-30 6.1 -6.2 6.8e-10 -0.99 0.01 0.99 FALSE
15 YFS Blood PRMT6 0.32 0.34 enet 28 0.36 6.6e-123 6.1 -5.8 7.1e-09 -0.95 0.01 0.99 FALSE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 6.1 -6.2 6.2e-10 -0.97 0.01 0.99 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma PRMT6 0.10 0.15 lasso 3 0.16 1.2e-30 6.0 -6.1 8.4e-10 -0.98 0.01 0.99 FALSE
18 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PRMT6 0.09 0.03 blup 36 0.07 1.8e-04 5.9 -5.5 2.9e-08 -0.77 0.01 0.94 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma PRMT6 0.19 0.20 lasso 4 0.24 2.4e-14 6.1 -6.0 1.5e-09 -0.96 0.01 0.99 FALSE
20 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 6.0 -6.2 5.9e-10 -0.97 0.01 0.99 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PRMT6 0.16 0.17 lasso 6 0.17 8.4e-19 6.1 -6.1 1.3e-09 -0.96 0.01 0.99 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRMT6 0.08 0.11 lasso 4 0.11 1.1e-12 6.1 -6.1 1.1e-09 -0.97 0.01 0.99 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRMT6 0.06 0.08 lasso 3 0.06 1.6e-04 6.1 -6.1 1.4e-09 -0.96 0.01 0.98 FALSE
24 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PRMT6 0.29 0.28 lasso 4 0.28 2.6e-13 5.9 -6.0 2.4e-09 -0.95 0.01 0.99 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma PRMT6 0.17 0.22 lasso 3 0.22 4.8e-25 5.9 -6.0 2.2e-09 -0.96 0.01 0.99 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 6.1 -6.2 4.2e-10 -0.96 0.01 0.99 FALSE
27 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 6.1 -6.4 2.0e-10 -0.94 0.01 0.99 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma PRMT6 0.17 0.17 enet 6 0.19 1.5e-13 6.1 -6.1 8.5e-10 -0.98 0.01 0.99 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma PRMT6 0.38 0.26 lasso 6 0.28 1.1e-27 6.2 -5.7 1.0e-08 -0.97 0.00 1.00 FALSE