Best TWAS P=8.76e-09 · Best GWAS P=5.19e-09 conditioned to 0.00328
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TTLL7 | 0.11 | 0.01 | enet | 13 | 0.01 | 3.1e-02 | -5.2 | -5.8 | 8.8e-09 | -0.61 | 0.03 | 0.96 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | TTLL7 | 0.10 | 0.10 | lasso | 8 | 0.09 | 4.3e-12 | -5.5 | 5.5 | 3.1e-08 | 0.64 | 0.02 | 0.98 | FALSE |