TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
←
→
chr1:83,640,176-85,162,753
Best TWAS P=8.76e-09 · Best GWAS P=5.19e-09 conditioned to 0.00328
83.6M
83.8M
84M
84.2M
84.4M
84.6M
84.8M
85M
85.2M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
TTLL7
0.11
0.01
enet
13
0.01
3.1e-02
-5.2
-5.8
8.8e-09
-0.61
0.03
0.96
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
TTLL7
0.10
0.10
lasso
8
0.09
4.3e-12
-5.5
5.5
3.1e-08
0.64
0.02
0.98
FALSE