TWAS
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Genes
Traits
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Traits
:
Leg fat mass (left)
:
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→
chr14:90,643,934-92,213,967
Best TWAS P=2.33e-07 · Best GWAS P=9.47e-09 conditioned to 0.0125
90.6M
90.8M
91M
91.2M
91.4M
91.6M
91.8M
92M
92.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
RPS6KA5
0.08
0.07
lasso
2
0.06
5.3e-05
-5
5.2
2.3e-07
-0.89
0.07
0.9
TRUE