Best TWAS P=1.11e-10 · Best GWAS P=6.02e-10 conditioned to 0.111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DPY19L3 | 0.07 | 0.05 | lasso | 2 | 0.06 | 8.7e-08 | -5.1 | -5.2 | 2.3e-07 | 0.01 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Mucosa | PEPD | 0.37 | 0.32 | enet | 20 | 0.39 | 9.5e-28 | 4.8 | 5.6 | 1.9e-08 | 0.71 | 0.03 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PEPD | 0.06 | 0.01 | blup | 114 | 0.04 | 2.6e-04 | 6.1 | 5.7 | 1.5e-08 | 0.84 | 0.01 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | PEPD | 0.13 | 0.06 | blup | 113 | 0.10 | 1.2e-06 | 4.7 | 6.5 | 1.1e-10 | 0.81 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PEPD | 0.16 | 0.07 | lasso | 3 | 0.05 | 3.1e-03 | 6.1 | 6.0 | 1.4e-09 | 0.79 | 0.01 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | DPY19L3 | 0.05 | 0.04 | enet | 9 | 0.05 | 2.1e-05 | -4.7 | -5.2 | 1.9e-07 | -0.01 | 0.02 | 0.97 | TRUE |