TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
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→
chr2:134,928,375-137,323,986
Best TWAS P=4.03e-08 · Best GWAS P=7.24e-08 conditioned to 0.213
135M
135.5M
136M
136.5M
137M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
MCM6
0.18
0.15
enet
20
0.20
8.5e-64
-5.4
-5.5
4.0e-08
0.87
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
LCT
0.04
0.02
blup
36
0.02
1.9e-03
-4.6
5.4
6.8e-08
-0.97
0.01
0.97
FALSE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
LCT
0.09
0.04
blup
36
0.05
4.9e-04
-5.4
5.3
1.3e-07
-0.89
0.00
0.87
FALSE
1
CommonMind
Brain Pre-frontal Cortex
LOC100129961
0.17
0.14
enet
9
0.14
2.6e-17
4.8
5.3
1.4e-07
-0.51
0.02
0.97
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
LCT
0.02
0.02
enet
3
0.03
7.6e-07
-5.4
5.2
2.0e-07
-0.95
0.00
1.00
FALSE