[Hub]/) : Traits : Leg fat mass (left) :

chr2:99,468,341-101,731,705

Best TWAS P=1.7e-14 · Best GWAS P=4.06e-14 conditioned to 0.0399

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CHST10 0.05 0.02 blup 474 0.04 1.0e-05 5.0 -5.2 1.5e-07 0.59 0.51 0.47 FALSE
2 GTEx Adrenal Gland CHST10 0.18 0.04 lasso 4 0.05 5.6e-03 -5.4 5.2 1.9e-07 -0.70 0.30 0.21 FALSE
3 GTEx Artery Aorta AFF3 0.14 0.06 lasso 5 0.07 1.2e-04 -7.5 -7.7 1.7e-14 0.84 0.01 0.99 TRUE
4 GTEx Muscle Skeletal LONRF2 0.07 0.08 lasso 4 0.08 2.5e-08 -5.5 -5.5 4.3e-08 0.54 1.00 0.00 FALSE
5 GTEx Skin Sun Exposed Lower leg LONRF2 0.05 0.03 lasso 2 0.02 9.3e-03 5.5 -6.2 7.8e-10 0.56 0.33 0.09 FALSE
6 GTEx Thyroid CHST10 0.05 0.05 lasso 5 0.03 2.6e-03 -5.4 -6.3 3.9e-10 0.60 0.39 0.41 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LONRF2 0.06 0.04 blup 69 0.04 3.4e-05 5.2 -6.3 2.8e-10 0.68 0.38 0.61 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LONRF2 0.05 0.08 lasso 2 0.08 2.9e-05 5.6 -5.5 3.4e-08 0.66 0.20 0.20 FALSE