[Hub]/) : Traits : Leg fat mass (left) : ← →

chr2:99,468,341-101,731,705

Best TWAS P=1.7e-14 · Best GWAS P=4.06e-14 conditioned to 0.0399

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Aorta	AFF3	0.14	0.06	lasso	5	0.07	1.2e-04	-7.5	-7.7	1.7e-14	0.84	0.01	0.99	TRUE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LONRF2	0.06	0.04	blup	69	0.04	3.4e-05	5.2	-6.3	2.8e-10	0.68	0.38	0.61	FALSE
6	GTEx	Thyroid	CHST10	0.05	0.05	lasso	5	0.03	2.6e-03	-5.4	-6.3	3.9e-10	0.60	0.39	0.41	FALSE
5	GTEx	Skin Sun Exposed Lower leg	LONRF2	0.05	0.03	lasso	2	0.02	9.3e-03	5.5	-6.2	7.8e-10	0.56	0.33	0.09	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LONRF2	0.05	0.08	lasso	2	0.08	2.9e-05	5.6	-5.5	3.4e-08	0.66	0.20	0.20	FALSE
4	GTEx	Muscle Skeletal	LONRF2	0.07	0.08	lasso	4	0.08	2.5e-08	-5.5	-5.5	4.3e-08	0.54	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CHST10	0.05	0.02	blup	474	0.04	1.0e-05	5.0	-5.2	1.5e-07	0.59	0.51	0.47	FALSE
2	GTEx	Adrenal Gland	CHST10	0.18	0.04	lasso	4	0.05	5.6e-03	-5.4	5.2	1.9e-07	-0.70	0.30	0.21	FALSE