Best TWAS P=9.85e-08 · Best GWAS P=1.96e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | IGFBP2 | 0.09 | 0.04 | enet | 14 | 0.05 | 4.8e-07 | 5.2 | 5.2 | 1.6e-07 | 0.91 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SMARCAL1 | 0.10 | 0.04 | lasso | 5 | 0.04 | 5.6e-04 | 5.2 | -5.1 | 2.8e-07 | -0.92 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Esophagus Mucosa | SMARCAL1 | 0.19 | 0.11 | lasso | 3 | 0.09 | 9.4e-07 | 5.2 | -5.3 | 1.4e-07 | -0.98 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | SMARCAL1 | 0.13 | 0.13 | lasso | 2 | 0.11 | 1.3e-06 | 5.2 | -5.3 | 9.9e-08 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | GTEx | Stomach | SMARCAL1 | 0.16 | 0.06 | lasso | 4 | 0.06 | 1.1e-03 | 5.2 | -5.2 | 1.9e-07 | -0.96 | 0.01 | 0.94 | FALSE |