Best TWAS P=4.43e-16 · Best GWAS P=3.55e-15 conditioned to 0.000156
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 7.9 | 7.9 | 3.4e-15 | 0.98 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 7.6 | 7.6 | 2.7e-14 | 0.60 | 0.07 | 0.89 | FALSE |
| 3 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 5.6 | 6.8 | 1.3e-11 | 0.62 | 0.10 | 0.89 | FALSE |
| 4 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 7.8 | 6.8 | 1.0e-11 | 0.88 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 7.7 | 8.1 | 4.4e-16 | 0.59 | 0.02 | 0.68 | TRUE |