[Hub]/) : Traits : Leg fat mass (left) : ← →

chr3:182,655,858-184,238,310

Best TWAS P=1.66e-08 · Best GWAS P=1.6e-08 conditioned to 0.111

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KLHL24 0.42 0.60 bslmm 493 0.66 4.5e-107 -5.2 -5.1 2.8e-07 -0.20 0.05 0.95 FALSE
2 GTEx Adipose Subcutaneous KLHL24 0.15 0.10 lasso 6 0.10 1.4e-08 -5.2 5.6 1.7e-08 0.33 0.05 0.95 TRUE
3 GTEx Brain Caudate basal ganglia KLHL24 0.22 0.21 lasso 3 0.19 3.5e-06 -5.2 5.2 1.6e-07 0.25 0.05 0.92 FALSE
4 GTEx Brain Cortex KLHL24 0.21 0.15 lasso 3 0.07 6.1e-03 -5.2 5.6 2.7e-08 0.35 0.05 0.85 FALSE
5 GTEx Breast Mammary Tissue KLHL24 0.25 0.13 lasso 5 0.11 3.4e-06 -5.2 5.3 9.9e-08 0.30 0.05 0.95 FALSE
6 GTEx Esophagus Muscularis KLHL24 0.10 0.12 lasso 1 0.09 4.4e-06 -5.2 5.2 1.7e-07 0.25 0.05 0.95 FALSE
7 GTEx Nerve Tibial KLHL24 0.08 0.06 lasso 3 0.05 1.5e-04 -5.2 5.2 1.8e-07 0.25 0.05 0.93 FALSE
8 GTEx Skin Sun Exposed Lower leg KLHL24 0.09 0.06 lasso 10 0.05 9.5e-05 -5.2 5.2 2.2e-07 0.24 0.05 0.94 FALSE
9 GTEx Testis KLHL24 0.17 0.10 lasso 4 0.10 4.0e-05 -5.2 5.2 1.8e-07 0.25 0.05 0.94 FALSE
10 METSIM Adipose MAP6D1 0.06 0.05 bslmm 473 0.06 2.3e-09 5.4 5.5 4.2e-08 0.68 0.10 0.90 TRUE