TWAS
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Traits
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Traits
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Leg fat mass (left)
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chr4:275,902-1,610,872
Best TWAS P=5.86e-08 · Best GWAS P=5.84e-06 conditioned to 0.186
0.2M
0.4M
0.6M
0.8M
1M
1.2M
1.4M
1.6M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
SLC26A1
0.12
0.06
bslmm
400
0.08
8.0e-10
4.0
5.4
5.9e-08
0.42
0.02
0.76
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
PCGF3
0.03
0.00
blup
69
0.01
3.7e-03
3.2
5.3
9.5e-08
0.44
0.00
0.02
TRUE