Best TWAS P=4.83e-08 · Best GWAS P=1.78e-06 conditioned to 8.27e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | CTC-228N24.3 | 0.15 | 0.09 | lasso | 3 | 0.12 | 8.0e-15 | -4.5 | 5.2 | 2.5e-07 | -0.09 | 0.02 | 0.94 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FLJ33630 | 0.05 | 0.04 | enet | 14 | 0.03 | 2.1e-07 | -4.5 | 5.5 | 4.8e-08 | -0.06 | 0.00 | 0.96 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FLJ33630 | 0.08 | 0.05 | blup | 70 | 0.04 | 4.4e-05 | -4.2 | 5.4 | 5.7e-08 | -0.10 | 0.00 | 0.93 | FALSE |