TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
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chr9:95,640,381-97,136,378
Best TWAS P=7.21e-12 · Best GWAS P=4.36e-12 conditioned to 0.00654
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
97M
97.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
PHF2
0.07
0.06
lasso
5
0.04
5.5e-04
6.7
6.8
7.2e-12
0.75
0.02
0.97
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
PHF2
0.02
0.01
blup
104
0.01
4.6e-03
6.6
6.3
2.6e-10
0.69
0.01
0.92
FALSE
3
The Cancer Genome Atlas
Esophageal Carcinoma
PHF2
0.29
0.14
blup
103
0.16
1.0e-05
6.4
5.7
1.6e-08
0.85
0.01
0.98
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
PHF2
0.07
0.03
blup
104
0.05
1.9e-06
6.4
5.2
1.8e-07
0.81
0.01
0.99
FALSE