[Hub]/) : Traits : Leg fat mass (left) :

chr9:102,162,230-103,803,109

Best TWAS P=8.9e-10 · Best GWAS P=4.35e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta INVS 0.15 0.10 enet 19 0.12 4.9e-07 5.8 5.2 2.6e-07 0.72 0.08 0.90 FALSE
2 GTEx Cells Transformed fibroblasts INVS 0.16 0.10 enet 17 0.17 8.0e-13 5.9 5.4 8.4e-08 0.61 0.06 0.94 FALSE
3 GTEx Esophagus Muscularis INVS 0.21 0.16 lasso 5 0.22 8.9e-14 5.9 5.2 1.9e-07 0.73 0.08 0.92 FALSE
4 GTEx Heart Atrial Appendage INVS 0.08 0.03 lasso 3 0.04 4.9e-03 -4.4 5.2 2.2e-07 0.77 0.08 0.85 FALSE
5 GTEx Heart Left Ventricle INVS 0.11 0.05 enet 15 0.04 2.6e-03 2.2 5.3 1.3e-07 0.72 0.04 0.84 FALSE
6 GTEx Muscle Skeletal INVS 0.12 0.03 lasso 10 0.10 1.3e-09 5.9 5.3 1.5e-07 0.73 0.05 0.95 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic TEX10 0.10 0.09 lasso 4 0.10 3.1e-06 4.3 5.5 3.9e-08 0.92 0.02 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg INVS 0.19 0.06 enet 30 0.11 1.5e-09 5.9 5.8 7.7e-09 0.79 0.02 0.98 FALSE
9 GTEx Skin Sun Exposed Lower leg TEX10 0.27 0.27 lasso 8 0.28 7.0e-23 6.2 6.1 8.9e-10 1.00 0.01 0.99 TRUE
10 YFS Blood INVS 0.15 0.14 lasso 7 0.24 1.4e-77 2.4 5.2 1.7e-07 0.78 0.02 0.98 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma INVS 0.27 0.05 lasso 8 0.13 3.4e-11 4.6 5.2 2.4e-07 0.68 0.14 0.86 FALSE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INVS 0.10 0.03 blup 107 0.07 4.0e-04 5.9 5.5 4.8e-08 0.89 0.02 0.95 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma INVS 0.08 0.06 blup 106 0.07 7.0e-09 -4.1 5.4 7.5e-08 0.70 0.79 0.21 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma INVS 0.09 0.02 enet 11 0.04 4.0e-05 4.6 5.5 4.8e-08 0.66 0.03 0.76 FALSE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma INVS 0.16 0.12 enet 8 0.08 2.8e-04 5.5 5.8 5.1e-09 0.77 0.06 0.91 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma INVS 0.09 0.04 enet 14 0.06 1.5e-06 4.6 5.2 1.9e-07 0.75 0.05 0.94 FALSE