[Hub]/) : Traits : Leg fat-free mass (left) :

chr6:44,079,216-46,043,561

Best TWAS P=2.31e-08 · Best GWAS P=6.17e-09 conditioned to 0.00156

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts SUPT3H 0.15 0.10 lasso 4 0.13 8.8e-10 5.1 -5.5 4.5e-08 -0.55 0.07 0.93 FALSE
2 GTEx Nerve Tibial SUPT3H 0.17 0.12 lasso 5 0.10 2.2e-07 5.2 -5.2 1.6e-07 -0.51 0.06 0.94 FALSE
3 GTEx Pancreas SUPT3H 0.11 0.07 lasso 2 0.05 3.6e-03 5.5 -5.5 4.4e-08 -0.52 0.06 0.83 FALSE
4 YFS Blood SUPT3H 0.06 0.09 lasso 13 0.12 2.2e-36 5.2 -5.6 2.3e-08 -0.58 0.10 0.90 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma SUPT3H 0.02 0.01 blup 191 0.01 3.0e-03 5.2 -5.4 5.6e-08 -0.45 0.04 0.96 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SUPT3H 0.04 0.01 blup 191 0.02 6.5e-03 -4.7 -5.4 5.9e-08 -0.47 0.06 0.91 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma SUPT3H 0.07 0.05 enet 12 0.08 1.1e-09 -4.5 -5.6 2.6e-08 -0.59 0.12 0.88 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma SUPT3H 0.03 0.03 lasso 2 0.02 8.9e-04 5.2 -5.5 3.0e-08 -0.55 0.05 0.84 FALSE
9 The Cancer Genome Atlas Stomach Adenocarcinoma SUPT3H 0.05 0.01 blup 191 0.00 1.4e-01 -4.1 -5.3 9.1e-08 -0.53 0.08 0.37 FALSE