[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr6:80,120,201-81,872,212

Best TWAS P=1.3e-15 · Best GWAS P=2.2e-13 conditioned to 0.538

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-3.5	-8.0	1.3e-15	-0.41	0.05	0.54	TRUE
9	GTEx	Muscle Skeletal	RP11-250B2.6	0.07	0.04	lasso	5	0.04	4.2e-05	7.2	-7.5	8.0e-14	-0.94	0.01	0.99	TRUE
4	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	4.2	7.4	9.8e-14	0.49	0.27	0.61	FALSE
1	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	6.0	-6.6	5.0e-11	-0.57	0.17	0.56	FALSE
5	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-6.5	-6.5	8.4e-11	-0.65	0.60	0.40	FALSE
10	GTEx	Testis	RP11-250B2.5	0.13	0.17	lasso	3	0.14	7.0e-07	-6.6	-6.5	1.0e-10	-0.88	0.05	0.94	FALSE
7	GTEx	Heart Left Ventricle	RP11-250B2.6	0.09	0.00	enet	6	0.02	2.0e-02	6.7	-6.4	1.7e-10	-0.82	0.03	0.82	FALSE
8	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	4.3	-6.3	3.5e-10	-0.36	0.80	0.06	FALSE
2	GTEx	Brain Cerebellum	RP11-250B2.5	0.43	0.11	lasso	5	0.14	4.7e-05	-6.7	-6.2	4.9e-10	-0.76	0.09	0.80	FALSE
11	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	4.3	5.8	5.5e-09	0.46	0.96	0.04	FALSE
12	METSIM	Adipose	RP11-250B2.6	0.04	0.04	lasso	12	0.02	1.7e-04	6.4	-5.8	7.3e-09	-0.60	0.60	0.20	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BCKDHB	0.12	0.06	lasso	4	0.06	4.2e-07	5.8	-5.6	2.1e-08	-0.75	0.32	0.67	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	4.5	-5.2	1.7e-07	-0.23	0.14	0.09	FALSE