[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr6:80,120,201-81,872,212

Best TWAS P=1.3e-15 · Best GWAS P=2.2e-13 conditioned to 0.538

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.0 -6.6 5.0e-11 -0.57 0.17 0.56 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -6.7 -6.2 4.9e-10 -0.76 0.09 0.80 FALSE
3 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 4.5 -5.2 1.7e-07 -0.23 0.14 0.09 FALSE
4 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 4.2 7.4 9.8e-14 0.49 0.27 0.61 FALSE
5 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -6.5 -6.5 8.4e-11 -0.65 0.60 0.40 FALSE
6 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -3.5 -8.0 1.3e-15 -0.41 0.05 0.54 TRUE
7 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 6.7 -6.4 1.7e-10 -0.82 0.03 0.82 FALSE
8 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 4.3 -6.3 3.5e-10 -0.36 0.80 0.06 FALSE
9 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 7.2 -7.5 8.0e-14 -0.94 0.01 0.99 TRUE
10 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -6.6 -6.5 1.0e-10 -0.88 0.05 0.94 FALSE
11 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 4.3 5.8 5.5e-09 0.46 0.96 0.04 FALSE
12 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 6.4 -5.8 7.3e-09 -0.60 0.60 0.20 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 5.8 -5.6 2.1e-08 -0.75 0.32 0.67 FALSE