Best TWAS P=1.49e-08 · Best GWAS P=2.29e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RMND1 | 0.02 | 0.00 | blup | 57 | 0.01 | 3.1e-03 | 3.8 | -5.2 | 1.7e-07 | -0.61 | 0.00 | 0.61 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | RMND1 | 0.16 | 0.10 | lasso | 7 | 0.12 | 1.6e-06 | 4.5 | -5.4 | 5.4e-08 | -0.81 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RMND1 | 0.07 | 0.06 | blup | 58 | 0.09 | 1.4e-10 | 4.5 | -5.2 | 2.2e-07 | -0.81 | 0.22 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | RMND1 | 0.05 | 0.06 | lasso | 2 | 0.07 | 4.3e-08 | 6.0 | -5.7 | 1.5e-08 | -0.96 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | RMND1 | 0.16 | 0.15 | enet | 7 | 0.09 | 2.7e-03 | 6.0 | -5.2 | 2.6e-07 | -0.92 | 0.00 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | RMND1 | 0.06 | 0.04 | blup | 57 | 0.06 | 4.9e-05 | 4.1 | -5.6 | 2.4e-08 | -0.82 | 0.03 | 0.88 | FALSE |