TWAS
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Traits
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Traits
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Leg fat-free mass (left)
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chr9:114,119,984-115,636,588
Best TWAS P=1.05e-08 · Best GWAS P=4e-07 conditioned to 0.88
114.2M
114.4M
114.6M
114.8M
115M
115.2M
115.4M
115.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
SUSD1
0.27
0.31
enet
52
0.34
2.8e-116
-4.6
5.7
1.0e-08
-0.87
0.10
0.88
TRUE
3
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
SUSD1
0.10
0.04
enet
9
0.08
5.5e-06
-4.7
5.4
6.3e-08
-0.71
0.03
0.94
FALSE
1
GTEx
Stomach
SUSD1
0.28
0.03
lasso
5
0.03
1.1e-02
-5.0
5.2
1.7e-07
-0.93
0.02
0.96
FALSE