Best TWAS P=1.05e-08 · Best GWAS P=4e-07 conditioned to 0.88
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | SUSD1 | 0.28 | 0.03 | lasso | 5 | 0.03 | 1.1e-02 | -5.0 | 5.2 | 1.7e-07 | -0.93 | 0.02 | 0.96 | FALSE |
| 2 | YFS | Blood | SUSD1 | 0.27 | 0.31 | enet | 52 | 0.34 | 2.8e-116 | -4.6 | 5.7 | 1.0e-08 | -0.87 | 0.10 | 0.88 | TRUE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | SUSD1 | 0.10 | 0.04 | enet | 9 | 0.08 | 5.5e-06 | -4.7 | 5.4 | 6.3e-08 | -0.71 | 0.03 | 0.94 | FALSE |