Best TWAS P=9.14e-10 · Best GWAS P=4.35e-10 conditioned to 0.0039
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | C9orf5 | 0.05 | 0.02 | enet | 14 | 0.03 | 2.2e-10 | 3.9 | -6.1 | 9.1e-10 | -0.40 | 0.75 | 0.25 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C9orf4 | 0.08 | 0.03 | blup | 80 | 0.02 | 9.8e-04 | 3.9 | -5.2 | 1.9e-07 | -0.31 | 0.10 | 0.75 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTNNAL1 | 0.09 | 0.00 | blup | 83 | 0.04 | 1.0e-04 | 2.4 | 6.0 | 2.1e-09 | 0.44 | 0.03 | 0.17 | TRUE |