TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat-free mass (left)
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chr9:111,080,029-112,581,047
Best TWAS P=9.14e-10 · Best GWAS P=4.35e-10 conditioned to 0.0039
111M
111.2M
111.4M
111.6M
111.8M
112M
112.2M
112.4M
112.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
C9orf5
0.05
0.02
enet
14
0.03
2.2e-10
3.9
-6.1
9.1e-10
-0.40
0.75
0.25
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
CTNNAL1
0.09
0.00
blup
83
0.04
1.0e-04
2.4
6.0
2.1e-09
0.44
0.03
0.17
TRUE
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
C9orf4
0.08
0.03
blup
80
0.02
9.8e-04
3.9
-5.2
1.9e-07
-0.31
0.10
0.75
FALSE