Best TWAS P=3.05e-10 · Best GWAS P=6.67e-11 conditioned to 0.0131
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RRAS2 | 0.08 | 0.06 | lasso | 5 | 0.07 | 5.7e-06 | -5.1 | 5.2 | 1.8e-07 | 0.18 | 0.3 | 0.69 | FALSE |
| 2 | GTEx | Testis | RRAS2 | 0.18 | 0.13 | enet | 19 | 0.15 | 2.7e-07 | -4.8 | 5.8 | 7.4e-09 | 0.21 | 0.1 | 0.90 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RRAS2 | 0.13 | 0.01 | blup | 11 | 0.05 | 4.0e-03 | 6.5 | 6.3 | 3.0e-10 | 0.80 | 0.0 | 0.93 | TRUE |