Hub : Genes

RRAS2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0600 0.0260 5.0e-03 0.020 0.006 0.027 0.018 0.037 1.5e-03 5.8e-02 2.8e-04 2.4e-03 2.2e-05
2 GTEx Adipose Subcutaneous 0.1070 0.0400 1.7e-04 0.023 NA 0.015 NA 0.020 5.3e-03 NA 2.0e-02 NA 9.0e-03
3 GTEx Artery Aorta 0.0600 0.0290 9.1e-03 0.056 NA 0.034 NA -0.003 5.1e-04 NA 5.6e-03 NA 5.4e-01
4 GTEx Artery Tibial 0.0832 0.0324 1.9e-04 0.061 NA 0.049 NA 0.067 1.6e-05 NA 1.1e-04 NA 5.7e-06
5 GTEx Cells Transformed fibroblasts 0.0860 0.0340 9.4e-04 0.106 NA 0.090 NA 0.098 2.6e-08 NA 2.9e-07 NA 8.1e-08
6 GTEx Lung 0.0529 0.0234 4.3e-03 0.034 NA 0.020 NA 0.045 1.3e-03 NA 1.1e-02 NA 2.2e-04
7 GTEx Testis 0.1770 0.0560 1.6e-06 0.131 NA 0.153 NA 0.114 2.1e-06 NA 2.7e-07 NA 9.4e-06
8 GTEx Thyroid 0.0890 0.0380 5.0e-04 0.020 NA 0.067 NA 0.048 9.8e-03 NA 7.6e-06 NA 1.4e-04
9 METSIM Adipose 0.0664 0.0257 1.6e-03 0.021 0.020 0.028 0.025 0.027 2.9e-04 3.9e-04 4.6e-05 9.6e-05 4.6e-05
10 YFS Blood 0.1638 0.0292 0.0e+00 0.139 0.177 0.187 0.183 0.168 4.1e-43 1.3e-55 8.5e-59 1.3e-57 1.3e-52
11 TCGA Lung Squamous Cell Carcinoma 0.0530 0.0269 1.1e-03 -0.001 0.022 0.015 NA 0.001 5.3e-01 1.3e-03 6.9e-03 NA 2.2e-01
12 TCGA Pheochromocytoma and Paraganglioma 0.1260 0.0650 7.1e-04 0.010 0.052 0.049 NA 0.039 1.2e-01 4.1e-03 5.1e-03 NA 1.1e-02
13 TCGA Prostate Adenocarcinoma 0.0542 0.0317 3.5e-03 0.006 0.024 0.016 NA 0.010 7.0e-02 1.3e-03 8.3e-03 NA 2.7e-02
14 TCGA Testicular Germ Cell Tumors 0.0820 0.0450 4.1e-03 0.026 0.046 0.031 NA 0.026 4.2e-02 9.9e-03 2.9e-02 NA 4.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 2.8 4.4 13.7 -3.3 -0.3 -2.7 -2.1 -0.8 -1.4 -2.0 -0.3 0.6 3.2 1.3 -3.7 -0.7 -2.4
Bipolar Disorder or Schizophrenia 0.6 1.5 5.1 -1.7 1.0 -1.4 -0.2 1.5 1.3 0.2 1.6 0.5 0.0 2.2 -0.8 1.4 0.1
Depressed Affect (Nagel 2018) 0.6 1.4 5.7 -1.6 -0.7 0.4 -0.5 -1.0 -1.4 -0.3 0.3 -0.6 2.4 0.9 -1.4 -0.7 -1.9
Depression (Nagel 2018) 0.9 1.4 3.3 -0.8 -1.5 -0.9 -1.6 -1.4 -1.6 -0.8 -0.4 -0.2 1.7 0.2 -0.6 -0.8 -1.8
Intelligence (Savage-Jansen 2018) 1.4 4.4 9.1 -1.1 2.8 1.7 2.6 3.0 2.9 2.1 1.8 2.2 -2.2 1.4 1.0 1.8 1.5
Neuroticism (Nagel 2018) 0.9 2.2 4.6 -1.4 -1.3 -0.8 -1.5 -1.5 -1.9 -1.5 -0.7 -1.4 2.2 -0.4 -1.6 -1.5 -1.9
Schizophrenia (2018) 1.8 3.7 7.7 0.4 1.5 0.4 1.5 2.7 2.8 1.9 2.3 0.1 -2.5 1.9 2.0 2.4 2.1
Schizophrenia vs Biploar Disorder 5.6 7.4 12.9 0.8 2.0 3.0 3.5 3.0 3.1 3.6 2.9 1.0 -3.0 2.0 3.2 2.8 2.6
Worry (Nagel 2018) 1.1 2.3 5.1 -0.5 -1.5 -1.6 -2.0 -1.0 -1.3 -1.9 -1.7 -1.4 1.0 -1.9 -1.3 -2.3 -1.1
Alzheimer’s Disease (in mother) 0.6 0.7 1.6 -0.4 -0.7 -0.8 -0.8 -1.2 -1.3 -1.2 -0.7 -0.1 1.1 -0.1 -0.4 -1.1 -0.7
Alzheimer’s Disease (in father) 1.5 1.7 4.3 -2.1 0.8 0.7 -0.0 0.8 0.3 0.9 1.3 1.3 1.4 1.6 -0.5 2.1 -2.0
Alzheimer’s Disease (including proxy) 1.1 1.6 5.2 -1.7 -0.4 -0.7 -1.5 -1.0 -1.4 -1.1 -0.6 0.6 2.3 0.2 -1.4 -0.3 -2.3
Crohns Disease (2017) 1.0 2.1 10.2 0.3 -1.5 -0.9 -3.2 -1.5 -1.4 -1.5 -0.6 -1.6 0.3 -1.2 -1.1 -1.9 -0.2
Irritable Bowel Disease (IBD) 0.2 0.4 1.6 -0.5 -0.1 -0.4 -1.3 0.5 0.5 -0.6 0.8 -0.6 -0.3 0.2 -0.6 -0.4 1.0
Ulcerative Colitis (UC) 0.6 1.1 3.1 -0.5 1.0 -0.1 0.8 1.6 1.7 0.2 1.4 0.3 -1.2 1.0 0.3 0.8 1.8
Major Depression (MDD) 0.3 0.3 1.1 -0.5 -0.6 -0.2 -0.4 -0.5 -0.6 -0.8 -0.2 -1.0 0.4 0.4 -0.7 -0.1 -0.7
Reaction Time 0.6 1.1 2.4 0.1 0.3 1.3 1.1 1.0 1.1 1.4 1.6 0.5 -0.3 1.6 0.8 1.1 1.0
Verbal and Numeric Reasoning (VNR) 2.8 6.7 11.4 -1.8 3.4 2.4 2.7 3.4 3.2 2.8 2.7 3.1 -1.0 2.6 1.2 2.8 1.4
Breast Cancer 0.6 1.5 6.2 -2.5 0.4 -0.8 0.0 0.1 -0.3 -0.8 1.1 -0.1 1.6 2.0 -2.0 0.0 -0.8
Ovarian Cancer 0.3 0.4 1.5 0.9 -0.8 -0.1 0.2 -0.9 -0.8 0.1 -0.4 0.2 -0.0 -1.2 0.7 -0.1 -0.9
Prostate Cancer 0.6 0.8 2.8 -0.8 1.0 0.2 0.2 0.7 0.4 1.1 1.7 0.9 1.2 1.2 -0.0 1.2 -0.3
Age at First Birth 0.2 0.3 1.5 0.1 -0.3 -0.3 -0.1 0.7 0.6 0.1 0.4 -1.2 -0.7 0.4 0.4 1.0 0.2
Bipolar Disorder (2011) 2.0 1.9 4.8 -1.4 -0.4 -2.2 -2.0 -0.7 -1.0 -1.4 -0.6 -0.2 1.7 0.5 -2.2 -1.0 -1.8
Body Mass Index (BMI) (2010) 3.0 4.1 8.7 -1.8 2.1 2.1 2.4 2.2 2.1 2.3 3.0 1.7 -1.1 2.7 -0.1 1.4 1.4
Coronary Artery Disease (CAD) 0.3 0.3 1.1 -0.1 0.9 0.1 -0.3 0.6 0.6 0.2 -0.2 0.4 -0.8 -1.0 0.4 -0.7 0.1
Crohns Disease (2012) 0.5 0.8 4.4 -0.0 -0.6 -0.4 -2.1 -0.7 -0.7 -1.0 0.2 -1.5 -0.1 0.8 -0.7 -0.8 0.5
Mean Putamen Volume 0.4 0.5 1.6 0.4 -1.2 -1.0 -0.8 -0.9 -0.9 -0.7 -0.5 -0.5 0.2 -0.2 -0.6 -0.3 -0.3
Fasting Glucose 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.2 0.3 0.5 0.5 -0.1 -0.2 0.7 0.3 -0.3 0.5
HbA1C 0.3 0.3 1.1 -0.8 -0.3 -0.3 -0.6 -0.5 -0.7 -0.5 0.7 0.7 -0.3 1.0 -0.6 0.3 -0.0
HDL Cholesterol 2.3 3.8 9.6 2.4 0.7 3.1 2.4 1.2 1.7 2.1 1.1 -0.2 -2.6 -1.1 3.0 1.9 1.2
LDL Cholesterol 0.9 1.4 5.0 -1.7 1.5 1.0 0.9 -0.1 -0.5 0.1 0.5 0.6 2.2 0.6 -1.6 0.7 -2.0
Lupus 0.6 0.9 4.0 0.7 0.2 -0.2 0.1 0.4 0.6 0.1 -1.6 -0.0 -0.2 -1.5 0.5 -2.0 1.5
Neuroticism (2016) 1.2 1.8 4.8 -2.1 -0.5 -1.2 -0.9 -1.1 -1.3 -1.3 -0.1 -1.0 1.7 1.5 -2.2 -1.1 -0.9
Primary Biliary Cirrhosis 0.4 0.5 3.9 0.4 -0.4 -2.0 -0.7 0.1 0.2 -0.8 -0.6 0.1 -1.0 -0.4 -0.2 -0.4 0.5
Rheumatoid Arthritis 0.9 1.2 4.2 0.8 0.4 -1.9 -0.1 1.0 1.3 0.6 -0.4 -0.5 -1.7 -0.3 1.3 -0.6 2.0
Schizophrenia (2014) 1.7 3.8 8.0 -0.6 1.5 -0.1 1.7 2.8 2.8 2.0 2.6 0.6 -2.0 2.5 1.4 1.9 2.1
Triglycerides 0.7 1.2 3.6 -0.9 -0.9 -1.1 -0.7 -0.9 -0.9 -1.6 -0.0 -1.5 0.2 0.8 -1.9 -1.6 0.3
Type 2 Diabetes (T2D) (2012) 0.6 0.7 3.0 0.6 -1.1 -1.7 -1.4 -0.6 -0.6 -0.7 -0.5 -1.0 -0.1 0.7 -0.6 0.1 -0.2
Ulcerative Colitis 0.7 1.0 3.9 -0.1 0.1 -0.4 0.6 1.3 1.5 -0.2 0.8 -1.1 -1.8 1.0 0.2 0.5 2.0
Blood Eosinophil Count 0.8 6.3 22.0 2.5 1.3 0.3 1.9 2.2 2.9 1.9 0.9 -0.1 -4.5 -0.2 4.0 0.3 4.7
Blood Platelet Count 0.3 3.2 7.5 -0.1 -2.3 -0.4 -1.7 -2.4 -2.7 -2.3 -2.0 -0.8 0.5 -1.2 -1.3 -1.8 -2.6
Blood Red Count 0.2 1.7 2.8 0.4 -1.6 -0.3 -0.5 -1.7 -1.6 -1.6 -1.6 -1.4 -1.5 -1.3 -0.7 -1.4 -1.1
Blood White Count 0.4 3.3 8.4 0.7 -1.7 -2.9 -2.0 -1.5 -1.4 -2.1 -2.8 -1.4 -0.7 -1.9 -0.6 -2.7 -0.0
Heel T-Score 0.1 1.2 4.7 0.9 -0.5 0.2 -0.6 -0.3 -0.2 -0.6 -1.9 -0.7 -0.8 -2.2 -0.2 -2.1 0.4
BMI 0.6 3.5 11.0 2.8 1.1 2.3 2.7 0.6 1.2 1.3 0.4 -0.0 -2.7 -1.6 3.3 0.9 1.7
Height 2.4 46.4 114.5 2.0 8.7 7.6 6.9 7.8 8.1 10.7 5.5 5.4 -3.0 2.9 7.3 9.0 3.7
Waist Hip Ratio (WHR) 5.4 24.5 56.0 -4.4 -2.7 -5.0 -5.5 -4.1 -5.2 -5.4 -3.7 -2.1 6.8 -2.4 -7.5 -3.5 -7.1
Systolic Blood Pressure 3.6 18.2 28.9 2.4 -5.4 -5.0 -5.4 -4.9 -4.6 -5.4 -5.3 -3.3 -0.7 -4.5 -2.9 -4.5 -1.9
Smoking Status 2.4 5.8 10.1 0.4 -2.9 -1.9 -2.7 -3.0 -3.2 -2.0 -2.4 -3.0 1.5 -2.7 -1.8 -1.9 -2.7
Allergy or Eczema 1.3 3.4 9.9 -0.6 1.4 0.9 2.3 2.0 2.1 1.8 3.1 1.8 -0.8 2.0 1.3 2.1 1.9
Cardiovascular Disease 1.2 3.8 7.7 0.5 -2.4 -2.8 -2.4 -2.3 -2.2 -2.4 -1.7 -1.7 0.8 -1.4 -2.1 -2.0 -0.8
Hypothyroidism (self reported) 0.1 0.2 0.7 0.2 0.4 -0.0 0.4 0.1 0.2 0.7 -0.3 0.4 -0.3 -0.8 -0.3 -0.4 0.0
Respiratory disease 0.3 0.6 1.6 0.0 0.4 0.7 0.9 0.9 0.9 0.9 0.8 0.5 -0.5 0.8 0.8 1.3 0.5
Type 2 Diabetes (T2D) (2018) 0.3 0.5 1.8 0.2 -0.4 -1.3 0.7 -0.1 0.1 -0.3 0.4 -0.2 -1.1 0.7 -0.6 -0.6 1.3
Lung FEV1/FVC ratio 0.1 0.6 1.9 1.3 -0.0 1.0 -0.6 -1.1 -0.9 -0.7 -0.7 -0.0 0.2 -1.4 0.5 -0.2 -0.4
Lung FVC 0.4 2.0 8.9 3.0 -2.0 1.6 0.1 -1.3 -0.9 0.2 -1.1 -0.9 -1.8 -1.4 1.8 0.5 0.3
Neuroticism 0.7 1.8 6.0 -2.3 -0.2 -0.8 -0.7 -0.3 -0.8 -0.7 -0.5 -0.7 2.5 -0.3 -2.2 -1.7 -1.7
Chronotype (morning person) 0.6 1.4 9.1 -0.7 -0.5 -1.0 0.0 -0.9 -1.0 -1.2 -1.2 -0.9 0.2 -1.1 -1.1 -3.0 0.4
Hair Pigment 0.0 1.0 3.6 -1.8 -0.0 -1.9 -1.1 -0.2 -0.5 -1.0 0.1 0.4 0.6 1.5 -1.3 -0.1 -0.5
Tanning 0.2 2.1 9.5 2.1 0.2 3.1 1.9 0.1 0.5 1.8 0.7 -1.1 -1.3 -0.0 1.6 0.9 1.3
Hand grip strength (left) 1.3 3.5 11.0 3.1 -1.5 -0.5 -0.6 -2.3 -1.9 -0.8 -3.3 -1.0 -2.4 -2.7 0.4 -1.3 -0.4
Number of treatments/medications taken 0.2 0.3 1.2 0.2 -1.1 -0.0 0.1 -0.9 -0.8 -1.0 0.5 -0.3 -0.1 0.6 -0.1 -0.7 0.3
Average weekly spirits intake 0.3 0.4 1.2 0.4 0.1 0.9 1.0 0.4 0.5 0.8 0.4 0.5 -0.5 -0.2 0.4 1.1 -0.1
Sensitivity / hurt feelings 0.4 0.7 1.9 -0.5 -0.2 -1.0 -0.9 -0.6 -0.6 -1.3 -0.6 -1.4 0.7 -0.9 -0.6 -1.2 -0.7
Frequency of depressed mood in last 2 weeks 0.9 1.3 2.9 -0.7 -1.2 -1.3 -1.5 -1.3 -1.5 -1.1 -0.8 0.2 1.7 -0.3 -0.6 -1.2 -1.4
Hearing difficulty/problems: Yes 1.0 1.5 6.3 -2.5 1.4 -0.7 0.2 1.0 0.4 0.3 0.1 1.5 2.0 0.8 -1.3 0.7 -1.5
Relative age of first facial hair 0.6 1.2 3.5 -1.2 -0.7 -1.6 -1.3 -0.8 -1.1 -1.2 -0.3 0.5 1.3 0.1 -1.4 0.0 -1.9
Other serious medical condition/disability diagnosed by doctor 1.6 2.0 4.9 -0.4 1.6 1.6 0.9 2.0 2.0 2.2 1.1 1.9 0.1 1.0 1.1 1.0 1.1
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.1 -0.2 0.1 0.7 -0.2 -0.1 -0.1 0.3 1.0 0.7 0.1 1.0 0.5 0.6 -0.1
Ever had hysterectomy (womb removed) 0.8 0.9 3.4 -1.8 0.2 -0.7 -0.1 -0.1 -0.4 -0.2 0.8 0.9 1.6 1.6 -1.1 -0.2 -0.8
Systolic blood pressure, automated reading 2.6 7.6 13.0 1.6 -3.6 -3.1 -3.3 -3.4 -3.1 -3.2 -3.5 -2.4 -0.8 -2.5 -1.6 -3.3 -0.9
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 1.3 0.0 -0.1 -0.7 1.1 -0.4 -0.3 -0.3 0.5 0.4 -0.2 0.4 -0.4 -0.1 0.4
Angina 0.3 0.3 1.2 -0.5 -0.3 -0.1 -0.3 -0.3 -0.4 -0.1 -0.6 1.0 1.1 0.4 -0.9 -0.1 -0.8
Medication for hormone replacement therapy 0.7 0.8 1.9 0.9 -1.4 0.8 -1.1 -1.0 -0.9 -0.6 -1.1 -1.3 -0.5 -0.3 0.5 -0.5 -0.5
Vitamin and mineral supplements 1.1 1.5 5.3 -0.6 -0.9 -0.8 -0.2 -1.4 -1.5 -1.4 -1.2 -0.8 0.5 -1.0 -2.3 0.0 -1.9
Supplements: Zinc 0.3 0.4 1.1 -0.6 1.0 -0.6 -0.2 0.9 0.7 0.8 -0.1 1.0 0.5 0.3 0.1 -0.1 0.2
Medication: Co-codamol 2.8 3.3 10.0 3.2 -2.3 -1.9 -1.0 -1.3 -0.7 -1.0 -1.1 -2.1 -2.7 -0.9 1.7 -1.4 2.2
Medication: Metformin 0.8 1.1 3.4 -1.6 0.6 -1.0 1.3 0.6 0.5 0.3 1.1 1.4 -0.6 1.8 -1.2 -0.3 0.6
Diabetes (father) 1.6 2.0 4.8 0.4 0.8 0.7 0.7 1.3 1.6 1.1 2.1 0.3 -1.2 2.0 2.0 1.5 2.2
Diabetes (mother) 0.9 1.2 3.5 0.7 -0.2 -0.9 -0.1 0.7 0.9 0.4 1.6 0.6 -1.6 1.1 1.9 0.8 1.6
Severe depression (siblings) 0.6 0.7 3.3 -1.2 0.7 0.3 0.2 0.8 0.7 0.5 1.8 -0.1 1.2 1.0 0.3 0.5 -0.0
Pack years adult smoking proportion 0.6 0.9 2.3 0.5 -1.1 -0.9 -1.0 -1.5 -1.4 -1.2 -0.9 -0.2 0.1 -0.6 -0.8 -1.2 -0.3
Impedance of leg (right) 0.6 3.0 8.4 -2.3 -1.1 -0.8 -2.4 -1.0 -1.6 -1.5 -0.3 -0.1 2.5 0.6 -2.9 -0.3 -2.8
Leg fat-free mass (left) 3.6 19.1 39.6 4.2 4.2 4.3 5.2 4.0 4.8 5.8 2.4 1.7 -5.0 0.2 6.3 4.7 4.3
Trunk fat percentage 2.7 11.0 19.8 2.3 3.2 4.0 3.8 3.1 3.6 4.4 3.0 1.7 -3.1 1.3 4.5 3.9 2.8
Hand grip strength (right) 0.4 1.1 3.9 2.0 0.2 -0.0 0.4 -0.9 -0.6 0.4 -1.8 0.3 -1.9 -1.6 0.6 0.1 -0.1
Townsend deprivation index at recruitment 1.0 1.4 5.6 -0.5 1.1 0.7 1.4 1.0 1.0 1.0 2.4 1.3 0.9 1.0 0.2 1.8 0.4
Current tobacco smoking 1.9 3.1 8.6 -0.8 -1.3 -1.0 -1.5 -2.1 -2.4 -1.0 -1.6 -0.1 2.5 -1.8 -2.2 -1.3 -2.9
Average weekly fortified wine intake 0.5 0.5 1.7 -0.9 0.3 -0.0 0.1 0.1 -0.1 0.6 -1.1 1.3 0.9 -0.7 -0.8 -0.4 -1.2
Maternal smoking around birth 1.4 2.1 5.7 0.5 -1.6 -2.4 -0.3 -1.3 -1.0 -1.2 -1.8 -2.1 -1.2 -0.8 -0.8 -2.4 0.5
Fed-up feelings 0.2 0.4 1.1 -0.8 0.5 0.9 0.7 -0.0 -0.2 0.7 1.0 0.1 1.0 0.7 -0.1 0.4 -0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.3 -0.5 -0.7 0.8 0.1 -0.9 -1.0 0.1 0.3 0.2 0.9 0.5 -0.3 0.1 -1.1
Relative age voice broke 1.0 1.5 5.8 -2.4 0.7 -1.5 -0.8 0.3 -0.1 -0.1 0.1 1.8 1.9 0.9 -1.3 -0.2 -1.5
Taking other prescription medications 0.7 1.0 3.3 -0.3 -1.8 -0.7 -0.8 -1.5 -1.5 -1.4 -0.4 0.3 0.6 0.2 -0.7 -1.1 -0.9
Age when periods started (menarche) 1.0 2.3 5.2 -0.0 -1.9 -0.5 -0.6 -1.9 -1.9 -1.9 -1.5 -2.1 0.4 -1.0 -2.3 -1.7 -1.3
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 4.0 0.2 -1.3 -0.3 -1.0 -1.2 -1.1 -0.9 -2.0 -0.5 -0.1 -1.9 -1.1 -1.9 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 5.6 1.6 -2.4 -0.4 -1.8 -1.6 -1.4 -1.9 -1.6 -1.7 -0.9 -1.7 -0.1 -1.4 -0.1
Tinnitus: Yes, but not now, but have in the past 1.9 2.0 7.9 -1.5 -1.4 -0.2 -0.9 -1.2 -1.7 -0.9 -0.1 0.9 2.8 0.4 -1.3 0.1 -2.7
Qualifications: CSEs or equivalent 1.2 1.5 6.5 2.3 -0.3 -0.2 0.0 0.2 0.6 0.3 0.8 -0.8 -2.5 0.0 2.1 0.6 1.7
Serious illness, injury or assault to yourself 2.8 3.4 8.6 0.3 1.3 0.8 1.6 2.1 2.3 1.8 2.9 0.4 -1.0 1.8 2.1 2.7 2.1
High blood pressure 1.1 3.2 9.1 -0.5 -1.7 -3.0 -2.2 -1.6 -1.7 -2.1 -1.6 -1.6 0.8 -0.5 -2.4 -2.2 -0.6
Hayfever, allergic rhinitis or eczema 1.6 3.6 7.6 0.9 1.2 1.2 2.0 1.9 2.2 2.0 2.8 1.3 -1.8 1.4 2.2 2.0 2.6
Multivitamins +/- minerals 0.7 0.9 4.2 1.2 0.3 0.7 0.1 0.5 0.7 1.0 0.2 0.4 -1.0 0.4 2.0 -0.5 1.7
Stomach or abdominal pain in last month 0.6 0.8 2.1 -0.3 -1.1 -0.7 -0.9 -1.4 -1.4 -1.2 0.2 0.1 0.7 0.3 -0.8 -0.1 -1.3
Supplements: Glucosamine 0.4 0.5 3.7 0.7 0.3 1.9 0.9 -0.0 0.1 0.8 -0.1 -0.3 -0.3 -0.3 0.5 -0.6 0.3
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.6 0.9 -0.8 -0.3 -0.9 -0.6 -0.5 -0.6 -0.4 -0.3 0.2 -1.2 0.3 -0.2 -0.4
Medication: Atenolol 0.5 0.7 2.0 -0.2 -0.5 -0.1 -0.8 -0.9 -0.9 -1.2 -1.1 -0.2 0.8 -0.3 -1.4 -0.6 -0.8
Medication: Levothyroxine sodium 0.1 0.2 0.5 0.3 0.6 0.6 0.7 0.2 0.2 0.7 0.2 0.7 0.3 -0.1 0.5 -0.1 0.4
Sitting height 2.2 15.7 32.0 3.8 2.9 4.0 3.8 3.6 4.3 5.3 2.4 1.8 -5.3 0.9 5.7 4.8 3.7
Chronic bronchitis/emphysema (father) 0.4 0.5 2.4 0.5 -0.3 -0.4 -0.5 -0.8 -0.8 -0.6 -0.6 -0.7 1.6 -0.9 -0.3 -0.7 -0.3
High blood pressure (mother) 1.2 1.6 6.2 -0.9 -0.7 -1.6 -1.0 -1.4 -1.6 -1.5 -0.7 -1.0 1.0 0.1 -2.5 -0.9 -1.3
Body mass index (BMI) 1.2 5.2 15.2 3.1 1.4 1.9 2.7 1.3 2.0 2.1 1.4 0.3 -3.5 -0.3 3.9 1.6 2.9
Impedance of leg (left) 0.9 4.2 12.0 -2.8 -1.1 -0.8 -2.6 -1.4 -2.0 -1.8 -0.4 -0.0 3.2 0.7 -3.5 -0.6 -3.2
Leg predicted mass (left) 3.6 19.0 39.0 4.2 4.2 4.3 5.3 3.9 4.8 5.8 2.3 1.7 -5.1 0.2 6.2 4.7 4.3
Trunk fat mass 3.6 15.3 30.0 3.1 3.8 4.5 4.5 3.5 4.3 5.2 3.1 1.9 -4.0 0.9 5.5 4.4 3.5
Waist circumference 0.9 3.2 9.0 2.4 1.6 2.3 2.2 1.2 1.6 2.1 0.7 0.4 -1.7 -0.9 3.0 2.2 1.0
Number of incorrect matches in round 0.7 1.1 2.7 -0.4 -1.1 -1.1 -1.6 -0.2 -0.4 -1.0 -1.2 -1.6 0.7 -0.6 -1.5 -1.3 -0.8
Past tobacco smoking 1.4 2.6 9.2 -0.0 1.8 1.2 1.8 1.8 1.9 1.8 1.5 3.0 -1.1 1.1 0.6 1.5 1.5
Alcohol usually taken with meals 1.1 1.8 4.6 1.1 -2.2 -1.0 -1.8 -1.9 -1.8 -1.5 -1.8 -1.2 -0.0 -0.4 -0.3 -0.6 -0.6
Nervous feelings 0.5 1.0 2.3 -0.3 -0.6 -0.6 -1.0 -0.7 -0.8 -1.2 -0.8 -1.0 1.1 -1.5 -1.3 -1.1 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 3.6 -1.6 0.5 0.6 0.4 0.5 0.1 0.6 0.3 1.4 1.9 0.4 -0.4 0.8 -1.9
Hearing difficulty/problems with background noise 1.2 1.9 10.1 -3.2 0.8 0.6 0.5 1.2 0.5 0.4 0.6 1.3 2.0 1.5 -1.1 0.6 -1.7
Hair/balding pattern: Pattern 2 0.7 0.9 3.0 -0.2 -1.1 -1.7 -1.3 -0.8 -0.8 -1.6 -0.5 -0.9 0.2 -0.3 -0.9 -0.7 -0.6
Had menopause 0.3 0.4 1.2 -0.6 0.3 0.7 0.1 0.7 0.6 0.1 1.1 0.9 0.6 0.8 0.4 0.9 -0.2
Had other major operations 0.2 0.3 2.0 -0.5 0.1 -0.4 -0.3 0.3 0.3 0.1 1.0 -0.1 -0.2 0.5 -0.3 1.4 -0.2
Forced vital capacity (FVC) 2.4 9.1 23.3 2.9 1.8 4.8 3.5 2.4 2.8 4.0 1.1 0.4 -3.9 -0.3 4.0 3.9 1.7
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.2 5.5 1.9 -2.4 -0.7 -1.6 -1.6 -1.5 -1.6 -1.8 -1.6 -0.9 -2.0 0.0 -0.9 -0.5
Ever unenthusiastic/disinterested for a whole week 1.4 1.7 3.2 -1.3 1.6 1.5 1.7 1.2 1.0 1.4 1.8 1.5 0.6 1.4 0.1 1.2 -0.4
Qualifications: None of the above 1.9 4.1 8.9 2.4 -2.6 -0.1 -0.1 -3.0 -2.5 -1.8 -2.3 -3.0 -0.6 -2.3 -0.2 -2.3 -0.7
Financial difficulties in last 2 years 0.3 0.4 1.8 1.3 -0.2 -0.8 0.2 -0.6 -0.4 -0.2 -0.1 0.2 -0.5 -1.1 0.5 0.4 0.1
Mouth/teeth dental problems 0.7 1.0 2.8 -0.7 1.1 0.4 1.1 0.8 0.9 0.8 1.6 -0.4 -0.4 1.7 -0.9 1.0 1.3
Heart attack 0.8 1.0 2.6 1.1 -1.6 -1.0 -1.0 -0.8 -0.7 -1.1 -0.7 -1.4 -0.8 -0.7 0.2 -1.3 0.8
Allergy 2.2 5.0 10.8 -0.7 -1.4 -1.0 -2.7 -2.5 -2.8 -2.4 -2.8 -1.2 2.3 -1.9 -2.3 -2.1 -3.3
Pain all over the body in last month 0.1 0.1 0.7 -0.0 -0.1 0.8 0.1 -0.3 -0.2 -0.2 0.4 -0.5 0.4 -0.0 -0.1 0.3 -0.2
Diabetes (self-reported) 0.4 0.6 3.2 -0.6 -0.1 -0.8 1.3 -0.1 -0.0 -0.2 1.1 0.3 -0.5 1.8 -0.6 -0.1 1.1
Hayfever/allergic rhinitis (self-reported) 2.1 2.8 6.0 0.2 1.3 2.4 2.1 1.7 1.7 1.7 2.5 1.3 -0.6 1.3 1.5 2.4 0.9
Medication: Ramipril 0.3 0.4 1.9 0.4 -0.0 -1.4 -0.3 0.3 0.5 -0.3 -0.6 -0.8 -0.4 -0.4 -0.1 -0.8 1.0
Medication: Simvastatin 1.5 2.2 6.3 -1.2 -1.3 -1.6 -1.0 -1.7 -1.9 -2.0 -0.6 -0.5 1.6 -0.1 -2.5 -2.0 -0.8
Fluid intelligence score 1.6 3.4 6.8 -1.2 2.5 2.6 2.1 2.4 2.3 2.0 1.1 2.6 -0.5 1.0 1.0 1.7 0.5
Illnesses of siblings 0.2 0.3 1.3 0.7 0.3 1.1 0.3 -0.3 -0.3 0.2 -0.5 -0.9 -0.0 -1.0 -0.1 -0.4 -0.0
Neuroticism score 0.7 1.4 4.2 -1.9 -0.4 -0.8 -0.5 -0.5 -0.8 -1.0 -0.3 -1.1 1.7 -0.2 -2.1 -1.6 -1.3
Weight 3.6 17.7 37.6 3.7 4.1 4.6 4.9 3.7 4.5 5.5 2.9 1.9 -4.5 0.5 6.1 4.7 3.8
Impedance of arm (right) 1.0 4.5 7.4 -2.2 2.5 2.7 1.6 2.3 2.0 2.7 2.5 2.0 1.4 2.5 0.1 2.7 -0.4
Arm fat percentage (right) 2.9 11.5 22.5 2.5 3.0 4.1 4.3 3.0 3.7 4.3 3.0 1.6 -3.5 0.9 4.7 3.5 3.4
Trunk fat-free mass 2.0 11.6 22.4 3.0 3.4 3.6 4.0 3.2 3.8 4.7 1.6 1.6 -4.0 -0.1 4.7 3.6 3.2
Hip circumference 5.6 24.1 60.0 5.4 3.5 5.8 5.4 3.9 5.0 6.0 2.8 1.7 -5.9 0.2 7.7 5.1 4.9
Time employed in main current job 0.7 0.9 2.6 -0.2 -1.1 -1.1 -0.5 -0.9 -0.9 -1.1 -1.4 0.1 -0.1 -1.0 -0.8 -1.6 -0.5
Alcohol intake versus 10 years previously 1.8 2.7 6.7 -0.5 1.6 1.3 1.6 1.8 1.9 1.7 2.2 1.0 -0.6 2.6 1.4 1.3 2.0
Father’s age at death 1.3 1.7 3.5 -1.9 1.6 1.1 1.7 1.6 1.2 1.3 1.3 1.1 1.2 1.2 -0.3 1.2 -0.5
Worrier / anxious feelings 0.7 1.3 3.5 -1.6 -0.6 -1.0 -0.6 -0.5 -0.8 -1.3 -0.8 -0.8 1.1 -0.9 -1.9 -1.6 -1.2
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 3.5 -1.6 -0.6 0.7 -0.3 -0.5 -0.9 -0.8 -0.2 0.4 1.8 -0.2 -1.0 -0.2 -1.9
Falls in the last year 2.1 2.9 7.3 0.3 1.6 1.6 2.7 1.6 1.8 2.1 2.0 1.0 -1.5 1.3 1.4 1.9 1.7
Hair/balding pattern: Pattern 3 1.0 1.4 3.8 -1.8 0.6 1.5 0.0 0.8 0.5 1.1 1.5 0.9 1.9 1.9 -0.1 1.2 -0.6
Number of live births 0.3 0.4 1.6 -0.2 -0.4 -0.9 -1.3 -0.4 -0.5 -0.9 0.5 -0.7 0.3 0.5 -0.6 0.2 -0.5
Forced expiratory volume in 1-second (FEV1) 1.9 6.4 15.1 3.2 1.4 3.9 2.6 1.6 2.1 3.0 0.2 -0.2 -3.8 -1.0 3.6 2.8 1.5
Pulse rate 2.3 4.0 10.4 0.5 -2.0 -3.2 -1.9 -2.2 -2.2 -2.1 -2.3 -1.5 -0.2 -2.2 -1.1 -2.6 -1.5
Happiness 1.5 1.8 5.2 -1.6 1.2 0.3 0.9 1.0 0.6 0.9 2.0 1.5 1.3 2.0 0.2 2.3 -1.1
Noisy workplace 0.3 0.4 1.1 1.0 -0.7 0.2 0.7 -0.9 -0.6 -0.2 -0.5 -0.9 -0.6 -0.2 0.3 -0.7 0.8
Qualifications: A levels/AS levels or equivalent 1.0 2.2 6.1 -1.8 2.0 0.9 1.2 2.5 2.1 1.5 1.1 1.7 0.2 0.7 -0.0 1.9 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.5 1.5 0.1 0.8 1.2 0.4 0.6 0.7 0.6 0.8 1.2 0.0 0.4 1.1 0.8 0.5
Mouth/teeth dental problems: Dentures 0.1 0.2 0.9 0.6 0.1 0.2 0.2 -0.3 -0.3 -0.2 -0.4 0.4 -0.1 -0.9 0.8 -0.7 0.0
Asthma 0.8 1.6 3.3 0.2 0.9 0.9 1.0 1.5 1.6 0.9 1.8 1.0 -0.9 1.0 1.7 1.8 1.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.6 1.4 -0.2 -0.6 -0.6 -0.4 -0.8 -0.9 -0.4 -1.2 -0.5 1.0 -0.8 -0.6 -0.6 -1.2
Medication: Cholesterol lowering 0.7 1.2 3.7 -0.7 1.1 1.1 1.4 0.7 0.8 1.2 1.9 0.4 0.4 1.7 -0.2 0.2 1.4
Depression (self-reported) 6.9 8.3 14.8 1.5 -3.7 -1.0 -3.4 -3.8 -3.7 -3.1 -3.3 -2.6 1.6 -3.3 -1.1 -3.4 -2.2
Medication: Lansoprazole 1.5 1.7 5.2 2.0 -2.3 -0.4 -0.5 -1.1 -0.7 -1.6 -0.8 -1.9 -2.1 -1.0 0.6 -0.5 0.4
Prospective memory result 0.4 0.5 1.3 0.5 -0.4 -1.0 -1.2 -0.2 -0.2 -0.6 -0.9 -1.1 -0.2 -1.0 0.1 -0.8 -0.2
Lung cancer (father) 0.8 0.9 3.3 -1.1 0.6 0.2 0.8 0.8 0.7 0.5 1.6 1.3 0.3 1.8 0.7 0.6 0.7
Illnesses of mother 0.4 0.6 1.5 -0.2 0.6 1.1 1.0 -0.0 -0.1 1.0 -0.3 0.5 1.1 -1.2 -0.4 0.1 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.1 10.9 2.8 1.1 3.3 2.1 0.8 1.2 2.2 0.5 0.2 -2.5 -0.9 3.0 2.9 0.6
Pulse wave Arterial Stiffness index 0.3 0.4 1.4 -0.4 0.6 -0.2 -0.0 -0.4 -0.4 -0.1 -1.0 0.2 1.2 -0.2 -0.8 -0.2 -1.1
Impedance of arm (left) 0.7 3.4 5.7 -2.1 2.2 2.4 1.1 1.9 1.5 2.2 2.0 1.7 1.8 2.2 -0.1 2.3 -0.6
Arm fat mass (right) 2.9 12.0 25.3 3.1 3.0 3.9 4.2 2.9 3.6 4.3 2.7 1.4 -4.0 0.5 5.0 3.6 3.5
Trunk predicted mass 2.1 12.0 23.0 3.0 3.5 3.6 4.1 3.3 3.9 4.8 1.7 1.6 -4.0 0.0 4.8 3.6 3.3
Standing height 2.4 23.3 57.2 1.5 6.1 5.7 5.0 5.5 5.7 7.6 3.4 3.4 -2.8 1.8 5.1 6.5 2.6
Length of working week for main job 1.1 1.2 3.4 -0.8 -0.6 -1.5 -1.3 -0.9 -1.2 -1.0 -0.5 0.4 1.2 -0.9 -1.8 -0.7 -1.6
Exposure to tobacco smoke at home 0.2 0.2 0.7 0.1 0.2 -0.5 0.2 0.4 0.5 0.1 -0.5 0.8 -0.4 -0.8 0.2 -0.7 0.5
Breastfed as a baby 1.4 1.7 3.3 -0.9 -1.1 -1.8 -1.8 -0.6 -0.8 -1.5 -1.8 -1.0 0.7 -1.0 -1.8 -1.7 -0.8
Tense / ‘highly strung’ 0.8 1.3 3.6 -1.1 -0.5 -0.8 -1.2 -0.8 -1.0 -1.3 -1.0 -0.9 1.9 -0.9 -1.3 -1.6 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.9 2.9 9.1 -1.0 -1.5 -1.1 -1.9 -2.1 -2.5 -1.9 -0.6 -0.9 2.0 -0.6 -1.8 -0.9 -3.0
Hair/balding pattern: Pattern 4 0.4 1.1 2.8 -0.8 1.6 1.0 1.5 1.5 1.5 1.7 0.6 0.5 0.0 0.2 -0.0 0.0 0.8
Birth weight of first child 0.6 1.2 2.4 -0.8 1.2 1.3 1.2 1.6 1.4 1.2 0.7 1.3 -0.5 1.0 0.6 1.3 0.1
Peak expiratory flow (PEF) 2.0 4.7 13.0 3.4 1.0 2.9 2.1 1.0 1.6 2.3 -0.1 -0.6 -3.6 -1.3 3.2 1.9 1.6
Pulse wave reflection index 0.4 0.4 1.5 -0.3 0.9 1.2 0.4 0.3 0.3 0.6 -0.4 0.8 0.8 0.1 -0.4 0.9 -0.8
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.1 -0.5 -0.2 -0.4 -0.3 -0.7 -0.8 -0.3 0.3 0.3 1.0 0.7 -1.1 0.4 -0.9
Loud music exposure frequency 0.3 0.3 1.4 -1.1 -0.0 -1.0 0.5 -0.0 -0.1 -0.2 0.2 0.4 -0.2 1.2 -0.8 -0.1 -0.3
Qualifications: O levels/GCSEs or equivalent 3.3 5.2 11.4 -1.9 3.4 1.0 2.0 3.2 3.0 2.5 2.7 2.8 -0.7 2.0 0.4 2.3 1.5
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 5.2 2.3 -1.0 0.0 -0.9 -0.6 -0.3 -0.0 -1.3 -0.6 -0.7 -1.5 2.1 0.3 -0.3
Blood clot in the leg (DVT) 1.2 1.6 3.8 0.3 1.3 0.6 2.0 1.1 1.4 1.9 1.0 0.9 -0.7 1.5 1.0 1.0 1.6
Medication: Paracetamol 0.2 0.4 1.6 0.2 -0.9 -0.8 -0.7 -0.7 -0.7 -1.2 0.1 -0.5 0.1 -0.1 0.2 -0.7 -0.1
Headache pain in last month 1.3 2.2 4.5 -0.0 -2.1 -1.1 -2.1 -1.5 -1.6 -1.8 -1.7 -1.3 0.5 -1.3 -1.2 -1.1 -1.9
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 1.5 0.5 -0.5 -0.4 -0.6 -0.4 -0.4 -0.7 -1.2 -0.4 -0.1 -1.2 0.5 0.1 -0.9
Glaucoma (self-reported) 0.4 0.5 1.6 -0.5 0.5 1.3 0.7 1.2 1.0 0.5 -0.0 1.1 0.2 0.3 -0.0 0.8 0.0
Gout (self-reported) 1.7 2.3 5.8 -0.8 -0.8 -2.1 -1.1 -2.1 -2.3 -1.5 -0.2 -1.0 2.4 0.3 -1.9 -1.4 -1.2
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.4 -0.1 1.2 1.0 1.6 1.1 1.2 1.6 0.6 1.2 -0.8 0.2 0.4 0.4 0.8
Medication: Amlodipine 0.4 0.5 1.6 -1.1 0.1 -0.1 0.4 0.4 0.2 0.2 1.2 0.8 1.1 0.8 -0.7 0.9 -0.7
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.9 0.7 -0.5 -0.8 -0.1 -0.3 -0.1 -0.5 0.2 -0.6 -0.4 0.2 0.8 -0.9 1.4
Birth weight 2.0 4.4 11.9 -1.8 3.1 3.5 2.3 2.4 2.0 2.2 1.4 1.6 0.9 0.4 0.3 3.2 -1.5
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.6 -0.5 1.3 0.1 -0.3 1.3 1.2 1.0 0.3 0.7 0.1 0.8 0.4 0.3 0.7
High blood pressure (siblings) 1.1 1.6 6.5 -0.9 -1.6 -2.5 -1.6 -0.9 -1.1 -1.8 -0.7 -0.2 0.7 0.4 -1.3 -0.8 -0.9
Forced vital capacity (FVC), Best measure 2.5 9.3 21.3 2.4 2.4 4.6 3.5 2.5 2.9 3.8 2.1 1.6 -3.1 0.3 4.1 4.5 1.6
Body fat percentage 2.2 8.9 17.4 2.3 2.7 3.7 3.5 2.6 3.1 3.8 2.7 1.4 -3.0 0.9 4.2 3.3 2.7
Leg fat percentage (right) 1.2 4.3 12.0 2.8 1.1 2.0 2.1 1.2 1.9 2.0 1.6 0.6 -3.1 0.0 3.5 2.1 2.3
Arm fat-free mass (right) 1.4 7.3 16.1 3.1 2.6 2.4 3.1 2.1 2.7 3.6 1.1 1.2 -3.5 -0.1 4.0 3.0 2.5
Exposure to tobacco smoke outside home 1.0 1.4 3.9 1.2 -1.5 -2.0 -0.5 -0.4 -0.1 -1.0 0.4 -1.9 -0.9 -0.1 0.9 -0.8 1.9
Comparative body size at age 10 0.3 0.9 3.6 -0.1 1.5 1.4 1.9 0.7 0.8 1.3 0.7 0.5 0.3 0.2 0.5 -0.1 1.1
Number of full brothers 0.6 0.8 2.8 1.0 -1.3 -0.5 -0.1 -0.3 0.0 -1.2 0.0 -1.7 -1.1 0.2 0.7 -0.6 1.1
Worry too long after embarrassment 0.7 1.1 4.9 -2.2 1.1 0.3 0.8 1.0 0.6 0.5 0.9 -0.2 1.9 0.7 -1.2 0.3 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.8 -0.9 -0.0 -0.3 -0.5 -0.2 -0.3 -0.8 -0.5 -0.5 0.3 -0.4 -1.7 -1.1 -0.2
Wheeze or whistling in the chest in last year 0.1 0.1 0.9 -0.0 -0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.5 0.1 -0.2 1.0 0.1 0.0
Number of children fathered 0.6 0.7 2.5 -1.6 0.9 -0.4 -0.8 0.2 -0.1 -0.2 0.2 1.0 1.4 1.1 -0.8 -0.1 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 2.6 -1.4 0.4 -0.6 -0.9 0.2 -0.1 -0.0 -0.1 0.3 1.6 0.6 -0.5 -0.2 -0.8
Age at first live birth 2.2 3.9 7.5 -1.3 2.4 2.4 2.1 2.7 2.5 2.3 1.9 1.8 -0.1 2.0 1.4 2.5 0.5
Pulse wave peak to peak time 0.4 0.5 1.5 0.3 -0.1 0.5 0.3 0.7 0.7 0.6 1.2 0.1 -1.1 0.5 0.9 0.6 1.1
Health satisfaction 1.2 1.5 4.7 -1.2 0.8 -0.6 1.2 1.3 1.2 1.0 1.5 2.1 -0.2 2.2 0.2 1.1 0.7
Shortness of breath walking on level ground 0.5 0.6 3.4 0.4 -1.0 -1.9 -0.5 -0.4 -0.3 -1.0 -0.4 -1.1 -0.1 -0.6 0.5 -0.8 0.2
Qualifications: College or University degree 0.6 1.8 6.5 -2.5 0.7 -1.7 -1.4 0.6 0.0 -0.8 -0.5 0.8 2.0 0.5 -1.8 0.5 -1.9
Eye problems/disorders: None of the above 0.7 0.9 4.2 0.9 -1.0 -0.7 -0.7 -1.2 -1.0 -0.9 -0.3 -2.0 -0.6 -0.9 -0.1 -0.8 0.0
Mouth/teeth dental problems: Loose teeth 2.3 2.7 6.3 -2.0 2.1 1.4 1.9 1.8 1.7 1.6 1.7 2.5 0.6 1.8 -0.3 1.5 -0.1
Emphysema/chronic bronchitis 0.2 0.2 1.4 -0.2 -0.2 -0.3 0.3 0.4 0.4 0.3 -1.2 0.1 0.3 -0.3 0.4 -0.5 -0.0
Medication for pain relief, constipation, heartburn 0.5 0.8 2.3 -0.0 1.3 1.2 0.7 1.0 1.0 1.5 -0.1 1.1 0.1 -0.1 0.2 1.4 -0.5
Neck or shoulder pain in last month 1.0 1.5 4.3 1.3 -1.4 -2.1 -1.5 -1.6 -1.4 -1.2 -1.1 -0.7 0.2 -1.3 -0.4 -0.8 -0.6
Medication: Blood pressure 0.4 0.8 2.4 -0.4 0.8 0.6 1.3 0.8 0.9 1.1 0.8 0.2 -0.5 1.5 -0.1 0.2 1.3
Angina (self-reported) 0.2 0.3 1.0 -0.2 -0.4 -0.3 -0.2 -0.4 -0.4 -0.1 -0.6 0.8 1.0 0.1 -0.6 -0.2 -0.6
Migraine (self-reported) 1.0 1.2 3.1 -1.1 -1.1 -1.1 -1.8 -1.0 -1.2 -1.3 -0.6 -0.3 1.0 0.0 -1.5 -0.6 -1.4
Medication: Ibuprofen 0.8 1.0 3.7 -0.3 -0.8 -0.5 -0.5 -1.2 -1.4 -0.7 -1.3 -0.2 1.6 -0.7 -0.7 -0.4 -1.9
Medication: Allopurinol 1.2 1.6 4.9 0.1 -1.2 -2.2 -1.6 -1.7 -1.7 -1.7 -0.1 -1.0 1.5 0.1 -0.7 -1.2 -0.2
Medication: Omeprazole 0.3 0.3 0.8 0.8 -0.9 -0.1 -0.5 -0.8 -0.6 -0.4 0.8 -0.9 0.4 -0.1 0.6 -0.0 0.3
Medication: Seretide 50 evohaler 0.7 0.8 3.2 1.5 -0.7 0.2 0.4 0.1 0.4 -0.0 0.3 -0.3 -1.8 0.6 1.5 0.2 1.5
Mean time to correctly identify matches 0.4 0.7 3.4 -0.7 -0.1 0.9 0.1 0.7 0.6 0.7 1.6 0.4 0.6 1.8 0.2 0.8 0.3
Heart disease (mother) 1.1 1.3 3.8 1.9 -1.0 -0.9 -0.4 0.1 0.5 -0.7 0.2 -1.5 -1.7 -0.1 1.7 1.0 1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.4 -0.6 -1.2 -0.7 -0.9 -0.6 -0.8 -1.1 -0.4 0.1 0.5 -0.0 -0.5 -0.8 -0.8
Whole body fat mass 3.1 12.8 25.3 3.1 3.4 4.2 4.3 3.0 3.7 4.7 2.7 1.6 -3.8 0.7 5.0 3.9 3.3
Leg fat mass (right) 2.4 9.3 22.3 3.5 2.4 3.2 3.5 2.2 3.0 3.6 1.9 1.0 -4.0 0.0 4.7 3.1 3.2
Arm predicted mass (right) 1.7 8.5 19.1 3.4 2.7 2.6 3.2 2.3 3.0 3.8 1.2 1.0 -3.8 -0.3 4.4 3.2 2.8
Pulse rate, automated reading 1.2 4.0 7.6 1.4 -2.5 -2.8 -1.9 -2.3 -2.2 -2.7 -2.1 -2.0 -1.2 -2.3 -0.3 -1.7 -1.1
Alcohol intake frequency. 0.2 0.4 2.5 -0.8 0.3 0.4 1.1 0.2 0.1 0.4 0.9 1.6 -0.2 0.2 -0.3 -0.5 0.1
Comparative height size at age 10 3.2 17.4 42.1 3.1 4.5 4.6 4.1 4.5 5.0 6.5 2.5 2.5 -3.4 0.2 5.4 5.0 3.1
Number of full sisters 0.4 0.5 2.3 -1.5 -0.5 -0.6 -0.4 0.1 -0.1 -0.7 0.0 0.5 0.5 -0.0 -1.3 -1.3 -0.2
Suffer from ‘nerves’ 0.4 0.6 3.5 -0.2 -0.4 -1.9 -0.8 -0.2 -0.2 -0.8 -0.7 -0.2 -0.1 -1.0 -0.5 -1.3 -0.0
Overall health rating 1.7 3.7 7.7 0.9 1.0 1.8 2.3 1.6 2.0 1.8 2.8 0.9 -1.8 1.9 2.3 2.6 2.2
Chest pain or discomfort 0.6 0.8 1.8 1.0 -0.0 1.1 0.1 1.0 1.2 0.7 -0.3 1.1 -1.1 -0.5 1.4 0.8 1.0
Had major operations 1.3 1.5 5.2 -1.8 0.8 -0.0 -0.1 0.5 0.3 0.2 1.4 1.8 1.9 2.3 -0.8 1.2 -1.0
Age at last live birth 1.2 1.8 6.0 -2.5 1.5 -0.1 0.1 1.4 0.9 0.6 1.2 1.7 1.4 1.8 -0.5 1.5 -1.1
Family relationship satisfaction 1.2 1.4 8.1 -1.9 0.6 -0.2 1.4 0.7 0.4 0.6 1.7 0.9 0.4 2.8 -0.7 0.9 -0.1
Leg pain on walking 0.8 1.0 6.2 -1.5 -0.1 -0.3 -0.6 -0.4 -0.6 -0.6 -0.2 1.0 2.5 0.3 -1.0 -0.6 -1.3
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 3.0 0.8 0.7 1.3 0.8 1.2 1.4 1.3 1.1 1.7 -1.5 0.3 1.2 0.8 1.6
Commuting to job workplace: Car/motor vehicle 1.6 1.9 3.8 1.8 -1.2 -1.6 -1.0 -0.9 -0.6 -1.5 -1.1 -1.3 -1.9 -1.2 1.0 -1.8 1.4
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 3.1 -0.9 0.2 0.3 -0.3 -0.2 -0.3 -0.2 -1.2 -0.1 -0.2 0.2 -1.8 -1.2 -0.0
Medication: Aspirin 0.3 0.3 1.2 -0.6 -0.9 -0.4 -0.3 -0.3 -0.4 -1.0 -0.3 0.3 -0.3 0.0 -1.1 -0.6 -0.6
Supplements: Vitamin C 0.8 1.0 4.2 0.6 0.7 -0.2 0.4 1.2 1.4 1.3 0.5 0.2 -0.4 -0.2 1.6 -0.8 2.0
Knee pain experienced in last month 1.0 1.6 5.0 2.2 -0.1 0.7 1.3 0.5 0.9 0.7 0.4 0.6 -2.1 -1.1 2.1 0.7 1.5
Hypertension (Self-reported) 1.2 3.4 9.0 -0.5 -1.9 -3.0 -2.2 -1.7 -1.8 -2.3 -1.8 -1.7 0.9 -0.6 -2.4 -2.3 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.1 -0.7 -0.4 0.0 -1.4 -0.3 -0.4 -1.1 -0.6 -0.2 1.5 -0.2 -0.4 -0.7 -1.2
Illnesses of father: Heart disease 0.1 0.2 0.9 -0.9 -0.4 -0.1 0.7 0.3 0.2 -0.0 0.2 -0.2 0.0 0.8 -0.3 0.1 0.3
Illnesses of siblings: Diabetes 0.8 0.9 3.1 0.1 0.9 -0.5 0.4 0.7 0.9 0.2 1.0 1.8 -1.2 1.3 0.8 0.8 1.3
Smoking status: Previous 0.6 0.9 6.4 0.5 -1.1 -0.6 -0.8 -0.8 -0.7 -0.8 -0.7 -2.5 -0.0 -0.4 0.5 -0.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.5 0.1 1.4 0.2 0.6 1.0 1.0 1.6 -0.2 1.2 -0.4 -0.6 0.5 0.8 -0.2
Whole body fat-free mass 2.7 15.4 30.4 3.6 3.8 4.0 4.6 3.6 4.3 5.3 2.0 1.6 -4.6 0.2 5.5 4.2 3.8
Leg fat-free mass (right) 3.3 17.8 35.5 3.9 4.2 4.3 5.2 3.8 4.6 5.7 2.3 1.8 -4.7 0.2 6.0 4.5 4.1
Arm fat percentage (left) 2.5 10.0 20.2 2.4 2.9 3.9 4.0 2.7 3.4 3.9 2.7 1.6 -3.2 0.7 4.5 3.2 3.1
Average weekly red wine intake 0.4 0.6 2.0 0.7 -1.1 -0.7 -0.9 -0.8 -0.7 -0.6 -1.4 -1.0 -0.2 -0.7 0.2 -0.7 -0.3
Handedness (chirality/laterality): Left-handed 2.6 3.1 8.0 1.0 -2.4 -0.4 -1.4 -1.8 -1.8 -2.4 -2.6 -2.8 -0.2 -1.8 -0.9 -1.8 -0.9
Mood swings 0.3 0.5 1.6 -0.6 -0.5 -0.4 -0.5 -0.7 -0.9 -0.6 -0.1 -0.5 1.2 0.2 -0.6 -0.4 -1.3
Loneliness, isolation 0.7 1.0 4.1 -2.0 0.1 0.6 0.8 -0.0 -0.3 0.0 1.3 0.5 1.3 1.4 -1.3 0.3 -1.3
Long-standing illness, disability or infirmity 0.4 0.6 2.0 -1.1 -0.1 0.1 0.4 0.4 0.3 0.7 1.1 1.1 1.0 1.4 -0.5 0.2 0.2
Ever had bowel cancer screening 0.2 0.2 1.6 -0.4 -0.3 -0.1 -0.4 0.1 0.0 -0.4 -0.0 -0.5 1.3 -0.3 -0.0 0.2 -0.6
Diabetes diagnosed by doctor 0.5 0.8 3.7 -1.1 -0.1 -1.2 0.9 -0.3 -0.3 -0.3 1.0 0.8 0.1 1.9 -1.4 -0.5 0.8
Ever had stillbirth, spontaneous miscarriage or termination 1.8 2.0 6.2 -2.3 -0.1 -0.3 -1.4 -0.4 -1.0 -0.7 0.2 0.7 2.5 0.3 -2.5 0.0 -2.3
Friendships satisfaction 0.5 0.7 2.7 -0.2 -0.7 -0.7 -0.6 -0.5 -0.8 -0.6 1.4 -0.5 0.6 1.6 0.4 1.0 -0.5
Qualifications: nursing, teaching 0.8 1.3 3.4 -1.8 1.0 -0.4 0.3 1.8 1.4 1.1 0.4 1.7 0.5 1.8 -0.1 0.6 0.4
Commuting to job workplace: Walk 0.4 0.5 2.1 -0.0 0.4 0.3 -0.4 -0.1 -0.2 0.8 0.5 1.3 0.3 0.9 -0.1 1.4 -0.9
Eye problems/disorders: Cataract 0.5 0.6 2.1 -1.0 1.0 0.5 0.8 0.5 0.2 1.2 -0.2 1.4 1.0 0.1 -0.7 -0.0 -0.7
Mouth/teeth dental problems: Mouth ulcers 1.9 3.0 7.6 0.6 -2.8 -1.7 -2.2 -1.9 -2.0 -2.0 -2.0 -1.0 0.2 -1.7 -0.5 -1.6 -2.0
Medication for cholesterol 3.2 4.8 12.5 -0.3 2.5 2.9 2.1 2.4 2.5 3.5 2.3 2.1 -0.6 1.7 1.9 2.2 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 1.7 0.9 -0.2 1.0 0.4 -0.4 -0.2 0.2 1.0 -0.0 0.6 0.5 1.3 0.9 0.1
Back pain experienced in last month 0.9 1.3 5.4 2.3 -1.3 -1.6 -1.4 -1.2 -1.0 -0.9 -0.8 -0.2 -0.6 -1.5 0.9 -0.0 -0.1
Mineral and other dietary supplements 0.7 1.0 5.2 -1.6 -0.3 -2.3 -0.3 -0.1 -0.3 -0.8 -0.4 0.6 0.5 0.2 -1.9 -0.1 -1.0
Breast cancer (self-reported) 0.2 0.3 0.9 0.9 -0.1 0.0 0.6 0.1 0.2 0.4 0.1 -0.6 -0.3 0.0 0.8 0.9 0.5
Asthma (self-reported) 1.1 2.3 5.2 0.6 1.0 1.0 1.4 1.7 1.9 1.1 2.0 0.8 -1.4 1.1 2.3 2.1 1.7
Osteoporosis (self-reported) 0.1 0.1 0.5 0.5 -0.0 0.3 0.4 0.0 0.1 0.6 -0.2 -0.2 -0.1 -0.1 0.7 0.0 0.0
Osteoarthritis (self-reported) 0.5 0.6 2.6 1.6 -0.9 -0.0 -0.8 -0.8 -0.5 -0.2 0.3 -0.7 -0.5 -0.6 0.6 -0.8 1.1
Medication: Aspirin 0.6 0.8 2.0 -0.4 -1.4 -0.8 -0.9 -0.9 -1.0 -1.4 -0.5 -0.0 0.1 -0.3 -1.3 -0.7 -0.9
Medication: Gliclazide 0.4 0.5 1.6 -0.5 -1.3 -1.3 0.3 -0.5 -0.6 -0.8 -0.2 -0.2 -0.4 0.5 -0.7 -0.8 -0.0
Illnesses of father: None of the above (group 1) 0.4 0.5 2.5 -0.2 1.5 0.5 0.2 0.6 0.6 0.6 0.0 1.6 0.3 -0.3 -0.3 0.4 -0.2
Smoking status: Current 2.4 3.8 9.1 -0.7 -1.6 -1.4 -1.8 -2.4 -2.8 -1.3 -1.8 -0.4 2.4 -1.9 -2.4 -1.5 -3.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.1 12.0 3.5 -0.2 2.8 1.3 -0.3 0.4 0.7 -0.2 -0.9 -3.0 -1.4 2.4 0.8 1.6
Whole body water mass 2.6 14.9 29.8 3.6 3.8 3.9 4.5 3.6 4.2 5.2 2.0 1.6 -4.5 0.1 5.5 4.2 3.7
Leg predicted mass (right) 3.2 16.9 34.5 3.9 4.1 4.2 5.0 3.7 4.4 5.6 2.2 1.7 -4.6 0.2 5.9 4.4 4.0
Arm fat mass (left) 2.7 11.2 22.8 3.0 3.0 3.9 4.1 2.8 3.5 4.2 2.6 1.4 -3.8 0.4 4.8 3.5 3.3
Number of self-reported non-cancer illnesses 0.3 0.6 2.2 1.2 -1.5 -0.1 0.0 -0.9 -0.7 -0.6 -0.1 -0.7 -0.9 -0.3 0.2 -0.6 0.7
Average weekly champagne plus white wine intake 0.2 0.3 1.1 -0.1 -0.2 -0.1 -0.9 0.0 -0.0 -0.8 0.6 0.0 0.5 0.6 0.2 1.1 -0.3
Miserableness 0.3 0.5 2.6 -0.8 -0.4 -0.3 0.1 -0.6 -0.8 0.2 0.6 -0.5 1.6 0.7 -0.5 -0.2 -0.9
Guilty feelings 1.3 2.0 4.2 -0.5 -1.6 -1.3 -0.7 -1.3 -1.3 -2.1 -1.5 -1.7 -1.0 -0.8 -1.9 -2.0 -0.5
Wears glasses or contact lenses 2.5 2.9 6.4 -1.4 2.5 1.0 1.3 2.4 2.2 1.7 1.8 2.2 -0.1 2.0 0.2 1.8 1.0
Ever taken oral contraceptive pill 1.3 1.5 5.2 1.6 -1.3 -0.2 -0.8 -0.7 -0.6 -0.4 -2.1 -1.5 -0.7 -2.3 0.8 -1.1 -0.1
Hearing aid user 1.8 2.0 4.3 -0.7 -0.6 -1.4 -1.4 -1.4 -1.6 -1.3 -1.5 0.7 1.6 -1.5 -1.8 -1.5 -2.1
Mother’s age at death 0.4 0.6 2.4 1.4 -0.1 1.1 0.0 0.2 0.3 0.1 -0.4 -0.4 -0.5 -1.1 1.6 0.4 0.1
Financial situation satisfaction 1.5 1.9 4.4 -0.7 1.7 -0.5 1.3 1.3 1.2 1.5 2.1 1.9 -0.2 1.9 1.1 1.4 1.0
Tinnitus: Yes, now most or all of the time 0.4 0.4 2.5 -0.2 0.6 0.6 0.4 0.2 0.1 0.1 -1.6 0.6 0.6 -1.0 -0.2 -0.8 -0.3
Commuting to job workplace: Public transport 2.6 3.1 9.9 -1.1 1.6 2.1 1.7 1.3 1.0 2.1 2.4 1.3 1.9 1.4 0.1 3.2 -1.1
Eye problems/disorders: Glaucoma 0.2 0.2 0.6 -0.4 -0.2 0.5 -0.0 0.6 0.5 -0.1 -0.2 0.5 0.5 0.4 -0.5 0.8 -0.3
Medication: Blood pressure 3.6 6.9 14.7 -0.1 -2.9 -3.6 -3.1 -2.9 -3.1 -3.8 -2.4 -2.3 1.0 -1.5 -3.1 -2.3 -2.0
Pain type(s) experienced in last month: Hip pain 0.5 0.6 2.8 1.7 -0.2 0.6 0.8 -0.5 -0.2 0.3 0.4 0.6 0.2 -1.1 1.7 0.3 0.2
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.6 1.2 -0.2 1.1 -0.0 -0.3 -0.2 -0.1 -0.1 -0.7 0.1 -0.5 1.2 -0.5 0.4
High cholesterol (Self-reported) 0.7 1.2 4.0 -0.8 -0.7 -0.6 -1.0 -1.4 -1.5 -1.2 0.2 -0.3 2.0 0.3 -1.7 -0.8 -0.9
Medication: Bendroflumethiazide 1.0 1.6 5.9 2.2 -1.1 -1.1 -1.2 -0.9 -0.6 -1.3 -1.4 -2.4 -0.7 -1.4 0.3 -0.4 0.5
Medication: Paracetamol 0.5 0.8 2.4 0.2 -1.5 -0.9 -1.2 -1.1 -1.3 -1.5 -0.3 -0.7 0.2 -0.5 -0.1 -0.9 -0.7
Medication: Lisinopril 0.5 0.6 1.6 0.2 -1.2 -1.0 -0.7 -0.7 -0.7 -1.3 -0.7 -0.6 -0.9 -0.4 -0.4 -1.1 -0.0
Medication: Atorvastatin 0.6 0.7 2.0 -0.2 0.6 0.1 0.5 1.0 1.1 0.3 1.4 0.1 -0.4 1.1 1.0 0.5 1.4
Illnesses of father: High blood pressure 1.6 2.0 5.6 0.5 -2.4 -1.0 -1.6 -1.7 -1.8 -1.7 -1.4 -0.8 0.4 -1.8 -0.4 -1.1 -1.6
Alcohol drinker status: Never 0.5 0.6 1.9 0.1 0.7 1.3 0.7 0.1 0.0 0.6 -0.5 1.0 0.4 -0.8 0.4 0.8 -1.4
Ever smoked 1.3 2.3 5.3 -1.0 -1.4 -0.5 -1.7 -1.6 -1.9 -1.5 -1.2 -2.3 1.6 -0.6 -1.4 -1.0 -2.1
Basal metabolic rate 3.1 16.9 33.9 3.9 4.0 4.2 4.8 3.7 4.5 5.5 2.3 1.7 -4.8 0.2 5.8 4.5 3.9
Leg fat percentage (left) 1.0 3.5 9.3 2.4 1.1 2.0 2.0 1.0 1.6 1.9 1.5 0.6 -2.6 0.1 3.0 1.7 2.1
Arm fat-free mass (left) 2.0 10.0 21.2 3.3 2.8 3.1 3.5 2.6 3.3 4.2 1.8 1.1 -4.1 0.1 4.6 3.6 3.0
Number of operations (self-reported) 1.2 1.8 5.5 -1.5 -0.4 -1.0 -0.7 -1.5 -1.8 -1.2 -0.1 0.4 2.0 1.1 -1.7 -0.0 -2.3
Average weekly beer plus cider intake 0.4 0.5 1.7 -0.3 0.6 0.4 1.0 0.4 0.3 1.0 1.3 0.8 0.7 0.5 0.4 1.0 0.0
Irritability 0.4 0.7 2.0 -1.4 1.0 0.8 0.1 0.6 0.3 0.6 1.1 0.2 1.2 1.4 0.1 0.9 -0.8
Risk taking 0.4 0.6 3.3 -0.8 -0.1 -0.7 -0.0 -0.8 -0.9 -1.0 -0.2 0.4 1.8 0.2 -0.5 -0.2 -1.0
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.2 -0.8 1.0 0.8 0.3 0.6 0.3 0.9 0.2 0.7 1.1 0.1 -0.4 0.2 -0.5
Fractured/broken bones in last 5 years 2.4 3.0 9.9 0.3 1.6 2.0 2.8 1.6 1.6 2.5 1.7 0.9 -0.6 1.1 1.3 3.1 0.2
Age started oral contraceptive pill 1.9 2.3 5.5 -1.4 2.2 1.3 2.3 2.4 2.1 1.8 0.8 1.4 0.5 1.0 0.3 1.2 0.6
Diastolic blood pressure, automated reading 3.5 10.7 16.8 3.0 -4.1 -3.9 -3.1 -3.5 -2.9 -3.6 -4.0 -3.7 -2.6 -3.6 -1.3 -3.8 0.3
Ever depressed for a whole week 0.6 0.7 3.7 -0.5 0.6 0.4 0.3 0.3 0.1 0.8 1.9 1.1 1.2 1.0 0.4 0.8 -0.3
Unable to work because of sickness or disability 0.4 0.5 2.3 1.5 -0.7 0.5 0.2 -0.7 -0.4 0.1 -0.4 -0.7 -0.9 -0.8 0.4 -0.0 0.5
Commuting to job workplace: Cycle 0.2 0.3 1.4 -0.3 0.4 -0.3 0.1 0.5 0.4 0.9 -0.7 1.2 -0.1 -0.0 -0.4 -0.1 -0.1
Myopia 3.4 5.0 9.7 1.4 2.3 2.7 2.3 2.6 2.9 3.1 1.5 -0.1 -1.6 0.5 3.0 1.9 2.6
Vascular/heart problems diagnosed by doctor 1.6 4.3 10.8 0.2 2.3 3.3 2.4 2.1 2.1 2.7 2.1 1.6 -0.6 0.7 2.6 2.7 0.7
Cholesterol lowering medication 4.3 6.3 15.4 -0.6 -2.5 -3.5 -2.5 -2.7 -2.8 -3.9 -2.3 -1.2 1.6 -1.8 -2.7 -3.2 -1.5
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.1 0.4 -0.4 0.6 -0.5 -0.7 -0.5 -0.2 1.1 -0.5 0.8 0.1 0.5 0.2 0.1
Pain experienced in last month 0.5 0.8 4.0 -2.0 0.9 0.5 0.1 1.0 0.6 0.3 0.3 0.4 0.9 1.4 -1.3 0.5 -0.4
Supplements: Calcium 0.6 0.7 3.1 0.7 0.8 1.8 0.3 0.4 0.4 1.1 0.6 0.8 0.3 0.2 1.0 1.4 0.1
Basal cell carcinoma (self-reported) 0.3 0.3 1.4 -0.4 0.4 0.0 0.3 0.6 0.5 0.5 0.5 1.2 0.3 0.8 0.4 1.0 -0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.2 1.1 -1.5 -1.0 -1.0 -0.8 -0.6 -0.9 -0.6 -1.2 -0.7 -0.5 0.2 -1.1 0.8
Deep venous thrombosis (DVT) (self-reported) 1.4 1.7 4.6 0.3 1.3 0.7 2.1 1.3 1.5 1.9 0.8 0.9 -1.1 1.5 1.0 0.9 1.7
Heart disease (siblings) 0.7 0.9 2.9 -0.6 0.7 0.4 1.7 0.8 0.9 0.7 1.2 1.3 -0.4 1.3 0.7 1.3 -0.0
Alcohol drinker status: Previous 0.5 0.5 2.6 0.2 -0.6 -0.3 -0.5 -0.6 -0.6 -0.7 -0.8 -0.4 0.5 -1.4 -0.0 -1.6 -0.0
Pack years of smoking 0.7 1.0 2.4 0.2 -1.2 -0.9 -1.2 -1.5 -1.5 -1.2 -1.1 -0.1 0.5 -0.3 -1.1 -1.3 -0.5
Impedance of whole body 0.3 1.7 6.1 -2.5 0.6 0.7 -0.8 0.3 -0.1 0.3 0.9 0.8 2.3 1.6 -1.7 0.9 -1.9
Leg fat mass (left) 2.1 8.0 18.8 3.3 2.3 3.2 3.3 2.0 2.8 3.4 1.7 0.9 -3.6 -0.1 4.3 2.8 2.9
Arm predicted mass (left) 2.1 10.8 22.7 3.4 2.9 3.5 3.8 2.8 3.4 4.4 1.9 1.3 -4.0 0.1 4.8 3.9 2.9