Best TWAS P=3.69e-09 · Best GWAS P=1.98e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | ZNF605 | 0.23 | 0.07 | lasso | 9 | 0.06 | 4.5e-03 | 6.4 | 5.9 | 4.0e-09 | 0.96 | 0.01 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | ANKLE2 | 0.06 | 0.01 | enet | 17 | 0.03 | 8.8e-04 | 6.3 | 5.5 | 3.8e-08 | 0.74 | 0.00 | 0.95 | FALSE |
| 3 | GTEx | Testis | EP400NL | 0.37 | 0.30 | lasso | 5 | 0.36 | 6.0e-17 | 5.0 | -5.4 | 6.0e-08 | 0.02 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ANKLE2 | 0.04 | 0.02 | lasso | 2 | 0.02 | 5.8e-06 | 6.2 | 5.9 | 3.7e-09 | 0.96 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | DDX51 | 0.05 | 0.04 | lasso | 2 | 0.05 | 8.1e-04 | 5.0 | 5.2 | 1.9e-07 | 0.00 | 0.01 | 0.89 | FALSE |