Best TWAS P=1.03e-07 · Best GWAS P=2.2e-10 conditioned to 0.000525
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 5.4 | -5.3 | 1.0e-07 | -0.86 | 0.06 | 0.93 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -4.0 | -5.2 | 2.2e-07 | -0.82 | 0.03 | 0.60 | FALSE |