[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr16:14,229,099-15,886,243

Best TWAS P=2.1e-13 · Best GWAS P=2.06e-10 conditioned to 0.722

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	NTR	Blood	PDXDC1	0.12	0.12	enet	26	0.15	1.3e-46	-6.3	7.3	2.1e-13	-0.84	0.01	0.99	TRUE
1	GTEx	Adipose Subcutaneous	NTAN1	0.05	0.03	lasso	2	0.04	6.7e-04	-6.3	6.8	1.5e-11	-0.93	0.01	0.97	FALSE
4	GTEx	Cells Transformed fibroblasts	RRN3	0.10	0.12	enet	13	0.13	6.3e-10	5.5	6.2	5.3e-10	-0.59	0.43	0.57	FALSE
8	GTEx	Heart Left Ventricle	RRN3	0.24	0.12	lasso	7	0.17	2.2e-09	5.4	-6.1	1.0e-09	0.39	0.40	0.53	FALSE
12	GTEx	Nerve Tibial	NTAN1	0.07	0.00	enet	14	0.00	1.7e-01	5.5	5.8	5.0e-09	-0.17	0.02	0.18	FALSE
15	NTR	Blood	NTAN1	0.01	0.00	bslmm	110	0.00	4.2e-02	5.5	5.8	5.8e-09	-0.23	0.02	0.04	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RRN3	0.36	0.14	lasso	5	0.20	4.5e-07	5.5	5.8	5.9e-09	-0.60	0.16	0.80	FALSE
11	GTEx	Muscle Skeletal	NTAN1	0.12	0.07	lasso	6	0.09	1.4e-09	5.4	5.8	6.5e-09	-0.46	0.51	0.48	FALSE
13	GTEx	Skin Sun Exposed Lower leg	RRN3	0.10	0.12	lasso	1	0.11	4.5e-09	5.5	5.5	3.0e-08	-0.48	0.45	0.55	FALSE
14	GTEx	Testis	RRN3	0.10	0.10	lasso	2	0.07	3.9e-04	5.5	5.5	3.0e-08	-0.48	0.10	0.21	FALSE
10	GTEx	Muscle Skeletal	RRN3	0.18	0.03	enet	17	0.11	5.7e-11	4.0	-5.5	3.1e-08	0.37	0.17	0.70	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	NTAN1	0.12	0.10	lasso	3	0.11	1.4e-13	5.4	5.5	4.5e-08	-0.48	0.56	0.44	FALSE
9	GTEx	Heart Left Ventricle	NTAN1	0.09	0.04	lasso	3	0.02	2.0e-02	5.5	5.4	5.4e-08	-0.48	0.02	0.71	FALSE
6	GTEx	Heart Atrial Appendage	NOMO1	0.19	0.12	lasso	6	0.10	3.7e-05	5.4	5.4	6.9e-08	-0.48	0.20	0.35	FALSE
7	GTEx	Heart Atrial Appendage	NTAN1	0.10	0.09	lasso	1	0.07	3.7e-04	5.4	5.4	8.4e-08	-0.49	0.04	0.45	FALSE
2	GTEx	Artery Tibial	RRN3	0.11	0.06	lasso	2	0.07	2.0e-06	5.5	5.3	9.5e-08	-0.49	0.46	0.53	FALSE
5	GTEx	Esophagus Mucosa	RRN3	0.13	0.13	lasso	4	0.13	3.2e-09	5.4	5.2	2.5e-07	-0.51	0.50	0.50	FALSE