Hub : Genes

PDXDC1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1750 0.0540 1.4e-09 0.068 0.089 0.095 0.089 0.094 1.1e-08 5.9e-11 1.3e-11 6.0e-11 1.5e-11
2 GTEx Adipose Subcutaneous 0.2250 0.0720 1.8e-03 0.068 NA 0.057 NA 0.078 3.0e-06 NA 1.8e-05 NA 5.6e-07
3 GTEx Cells EBV-transformed lymphocytes 0.2500 0.0890 3.8e-04 0.032 NA 0.049 NA 0.042 3.2e-02 NA 1.1e-02 NA 1.6e-02
4 GTEx Esophagus Mucosa 0.1300 0.0510 2.2e-04 0.000 NA 0.031 NA 0.024 3.3e-01 NA 3.7e-03 NA 9.4e-03
5 GTEx Esophagus Muscularis 0.2330 0.0680 4.3e-05 0.032 NA 0.106 NA 0.054 4.7e-03 NA 5.9e-07 NA 3.3e-04
6 GTEx Skin Sun Exposed Lower leg 0.2270 0.0640 4.5e-06 0.054 NA 0.080 NA 0.049 2.8e-05 NA 3.4e-07 NA 6.3e-05
7 GTEx Stomach 0.3510 0.1070 3.2e-03 0.026 NA 0.020 NA 0.032 2.0e-02 NA 3.9e-02 NA 1.2e-02
8 GTEx Testis 0.1930 0.0680 1.9e-04 0.136 NA 0.106 NA 0.092 1.3e-06 NA 2.1e-05 NA 7.1e-05
9 METSIM Adipose 0.1401 0.0464 2.9e-07 0.040 0.052 0.059 0.059 0.052 1.2e-06 2.6e-08 3.6e-09 3.0e-09 3.0e-08
10 NTR Blood 0.1210 0.0261 0.0e+00 0.123 0.143 0.152 0.148 0.151 2.2e-37 7.1e-44 1.3e-46 2.8e-45 2.0e-46
11 ROSMAP Brain Pre-frontal Cortex 0.3153 0.0618 0.0e+00 0.100 0.133 0.150 0.144 0.134 7.7e-13 1.1e-16 7.5e-19 5.2e-18 6.8e-17
12 TCGA Breast Invasive Carcinoma 0.0192 0.0124 3.4e-03 0.007 0.011 0.010 NA 0.007 1.0e-02 2.2e-03 3.2e-03 NA 1.0e-02
13 TCGA Brain Lower Grade Glioma 0.0329 0.0235 6.5e-03 0.002 0.009 0.023 NA -0.001 1.7e-01 2.9e-02 1.1e-03 NA 4.2e-01
14 TCGA Thyroid Carcinoma 0.2520 0.1500 1.5e-12 0.116 0.125 0.141 NA 0.117 2.5e-11 3.3e-12 1.3e-13 NA 1.9e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.4 2.1 7.8 0.6 0.0 -2.8 -1.9 0.5 -1.7 -0.2 -2.1 -0.6 -2.0 -0.1 1.6 0.9 1.8
Bipolar Disorder or Schizophrenia 1.9 4.6 17.4 1.3 -0.7 -3.1 -2.9 0.2 -4.1 -0.7 -1.4 0.1 -4.2 0.7 1.4 0.7 2.1
Depressed Affect (Nagel 2018) 0.8 1.6 4.7 0.7 0.0 -1.2 -1.8 0.3 1.4 0.7 -1.6 -1.5 0.3 -0.3 2.2 1.6 1.6
Depression (Nagel 2018) 0.4 0.6 1.5 -0.3 -1.0 0.3 -0.9 -0.1 0.8 -0.3 -1.0 -0.8 0.9 -1.2 0.8 0.3 0.8
Intelligence (Savage-Jansen 2018) 0.8 2.5 7.1 -0.9 -0.2 1.1 1.1 -2.4 -1.8 0.3 1.3 1.9 -1.7 0.7 -2.5 -2.7 -0.9
Neuroticism (Nagel 2018) 0.5 1.2 3.7 1.0 0.1 -1.2 -1.8 0.5 0.1 1.0 -1.5 -1.0 -0.7 0.1 1.5 0.4 1.9
Schizophrenia (2018) 1.5 3.1 15.0 1.4 -0.8 -1.6 -2.2 -0.2 -3.6 -0.6 -0.1 1.2 -3.9 1.2 0.6 0.3 1.2
Schizophrenia vs Biploar Disorder 1.4 1.9 9.9 1.5 0.0 1.4 1.3 0.5 0.1 -0.3 3.1 1.3 -0.9 2.6 -0.9 -0.4 -0.5
Worry (Nagel 2018) 0.6 1.3 3.5 1.1 -0.5 -1.1 -1.8 0.9 -0.8 0.7 -1.2 -0.8 -1.6 0.1 1.3 0.6 1.9
Alzheimer’s Disease (in mother) 0.2 0.3 0.7 -0.1 0.3 -0.7 -0.5 -0.8 -0.4 -0.6 -0.8 -0.8 -0.4 -0.3 -0.0 -0.4 0.0
Alzheimer’s Disease (in father) 1.1 1.2 4.7 -1.6 -1.2 0.4 0.5 -1.8 -0.5 -0.3 0.3 -0.5 0.6 -0.9 -1.5 -2.2 -0.9
Alzheimer’s Disease (including proxy) 0.4 0.5 1.8 -0.6 -0.1 -0.9 -0.3 -1.3 -0.7 0.2 -0.9 -1.0 -0.4 -0.7 -0.4 -1.2 0.3
Crohns Disease (2017) 0.8 1.8 6.3 2.1 -0.7 -0.4 -1.1 1.0 -1.2 1.1 -0.0 1.9 -2.5 1.2 1.0 1.4 1.3
Irritable Bowel Disease (IBD) 3.0 7.2 17.4 4.0 0.5 -2.5 -2.0 1.9 -0.6 1.7 -0.1 2.8 -4.2 2.9 2.8 3.7 3.6
Ulcerative Colitis (UC) 4.7 8.8 19.1 4.4 0.8 -3.0 -1.8 2.3 0.3 1.8 0.1 3.0 -4.0 3.3 3.3 4.3 4.3
Major Depression (MDD) 1.3 1.5 5.0 0.3 0.0 -1.3 -2.2 -0.6 0.4 -1.1 -2.2 -1.9 -0.1 -1.4 1.6 0.4 0.7
Reaction Time 0.3 0.6 1.6 -1.3 0.8 1.0 -0.2 -0.9 -0.7 1.0 -0.8 -0.1 -1.1 0.1 -1.0 0.6 -0.5
Verbal and Numeric Reasoning (VNR) 0.4 1.0 4.2 -1.6 -0.4 0.8 1.3 -2.0 -0.3 -0.0 0.1 0.9 0.0 -0.1 -1.2 -1.4 -0.7
Breast Cancer 0.7 1.6 3.4 -1.6 -0.2 0.9 -0.0 -1.7 -0.4 -0.2 0.6 -1.7 1.7 -1.4 -1.6 -1.3 -1.8
Ovarian Cancer 0.8 1.0 2.9 -1.2 -1.1 -1.3 -1.4 -1.1 -0.7 -0.3 -1.2 -0.2 -0.4 -1.2 -0.1 -1.7 0.2
Prostate Cancer 1.0 1.4 5.2 -1.2 -0.4 1.1 -0.1 -2.3 -0.4 -1.7 -0.2 0.1 -0.0 -0.7 -2.0 -1.3 -1.3
Age at First Birth 1.3 1.8 5.8 0.4 1.1 1.6 1.5 -0.2 0.1 1.0 0.8 2.4 -1.4 1.5 -1.7 -1.9 -1.1
Bipolar Disorder (2011) 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.2
Body Mass Index (BMI) (2010) 2.6 3.6 12.6 -1.9 0.3 2.8 2.9 -0.2 2.5 0.3 0.7 -1.4 3.6 -1.1 -1.5 -0.5 -2.3
Coronary Artery Disease (CAD) 1.8 2.1 6.9 2.6 0.0 -0.6 0.4 1.4 2.1 1.1 2.2 0.1 -0.5 1.8 1.7 1.8 0.5
Crohns Disease (2012) 0.7 1.2 6.0 1.6 0.0 0.1 -0.6 0.8 -1.0 0.5 0.2 1.3 -2.4 1.4 0.4 1.1 0.9
Mean Putamen Volume 1.0 1.1 3.8 -1.9 0.1 1.7 1.5 -0.1 -0.4 0.6 0.6 -0.2 1.6 -1.0 -1.1 -0.1 -1.1
Fasting Glucose 0.5 0.6 3.6 -0.1 0.7 0.0 0.5 0.3 1.0 -0.2 1.9 -0.9 1.4 0.1 0.1 0.0 -0.5
HbA1C 0.3 0.4 1.1 -1.1 0.4 -0.0 0.4 0.2 -1.1 0.1 -1.0 -0.3 0.1 -0.8 -0.3 0.6 -0.4
HDL Cholesterol 1.6 2.6 8.3 -1.8 -0.4 2.3 1.6 -2.1 -1.1 -0.6 1.0 0.6 0.8 -0.7 -2.9 -1.8 -2.4
LDL Cholesterol 0.7 1.2 4.5 -0.8 -1.3 1.3 -0.0 -0.9 -2.1 0.3 1.1 0.7 -0.3 -0.5 -1.5 -0.5 -1.6
Lupus 0.4 0.5 2.0 -1.4 -0.3 0.6 -0.6 -1.1 -0.1 -0.2 -0.9 -0.9 0.8 -1.2 0.0 0.4 -0.2
Neuroticism (2016) 2.1 3.0 14.7 2.1 0.9 -1.7 -0.5 2.7 0.5 1.0 -0.2 0.7 -0.8 1.1 2.0 3.8 2.0
Primary Biliary Cirrhosis 0.3 0.4 1.9 1.4 0.5 -0.1 0.0 1.0 -0.1 -0.8 0.6 0.6 0.1 0.5 0.8 0.7 0.4
Rheumatoid Arthritis 0.9 1.3 3.9 -1.2 0.0 1.5 0.6 -0.5 0.3 -0.0 -0.5 0.1 1.6 -0.8 -2.0 -1.9 -1.6
Schizophrenia (2014) 2.0 4.3 17.2 2.2 -0.4 -1.6 -2.2 0.6 -3.2 0.9 -1.2 3.2 -4.1 2.1 0.3 1.2 1.5
Triglycerides 5.2 8.4 24.7 3.4 1.5 -4.3 -1.8 3.4 0.9 2.0 -1.1 0.1 -2.8 1.9 5.0 3.3 4.3
Type 2 Diabetes (T2D) (2012) 0.7 0.8 4.5 -0.6 2.1 0.5 1.2 1.0 0.4 0.2 0.9 -1.2 0.9 0.2 0.1 0.3 -0.7
Ulcerative Colitis 2.7 4.0 8.9 3.0 0.0 -2.4 -0.8 1.7 -0.7 0.2 0.7 1.8 -2.7 2.9 1.8 2.6 2.8
Blood Eosinophil Count 0.9 7.3 21.3 -3.4 0.8 4.0 3.2 -2.1 -1.0 -0.2 2.6 -0.4 2.6 -1.1 -4.6 -2.8 -3.7
Blood Platelet Count 0.3 3.5 15.2 1.6 1.6 -1.5 0.1 2.6 1.2 1.4 0.7 -0.2 -1.3 1.0 3.9 2.3 2.9
Blood Red Count 1.2 11.6 32.9 3.5 0.7 -5.1 -3.3 3.4 0.8 2.2 -1.3 0.8 -3.3 1.4 5.7 4.6 5.1
Blood White Count 0.2 1.3 4.3 -0.1 1.2 -0.5 0.3 1.5 0.3 0.1 0.6 -2.1 1.1 -1.1 1.9 1.3 1.4
Heel T-Score 1.1 8.5 25.2 4.1 0.8 -4.2 -2.2 2.5 0.4 1.6 -1.8 -0.9 -3.7 1.4 5.0 3.2 4.0
BMI 1.5 9.0 28.8 -4.8 -1.5 1.5 0.4 -2.0 1.3 -0.3 -3.6 -3.4 5.4 -4.9 -1.7 -1.5 -3.1
Height 1.4 27.1 125.4 -5.8 -1.7 5.9 4.3 -2.4 4.2 -1.6 0.9 -5.5 11.2 -4.9 -4.2 -5.2 -6.1
Waist Hip Ratio (WHR) 0.3 1.6 5.3 0.5 -0.4 -2.3 -1.5 0.7 0.8 -1.1 -0.9 -0.7 -0.2 -0.9 2.0 1.8 1.4
Systolic Blood Pressure 0.6 3.0 7.0 1.1 0.6 -1.3 -0.7 2.0 0.6 2.1 -0.9 2.2 -2.2 1.6 2.6 2.4 2.0
Smoking Status 0.6 1.5 4.0 0.3 0.2 -2.0 -1.5 0.6 0.1 0.5 -1.8 -1.5 -1.1 -0.5 1.9 1.1 1.6
Allergy or Eczema 0.5 1.4 4.4 -0.4 0.2 1.9 1.4 -0.8 -0.6 0.8 1.1 1.8 -1.2 1.1 -2.1 -0.4 -0.9
Cardiovascular Disease 0.2 0.7 2.4 -1.5 -0.1 -0.7 0.7 0.7 0.4 0.2 -1.6 0.6 1.3 -1.1 0.2 -0.0 -0.4
Hypothyroidism (self reported) 1.8 4.0 10.1 2.8 2.0 -0.8 0.0 2.8 2.4 1.3 0.3 0.6 -1.0 2.0 3.2 2.6 2.5
Respiratory disease 1.4 3.1 9.7 -2.3 0.7 1.6 -0.0 -2.9 -2.0 -1.7 0.3 0.6 0.1 -0.2 -3.1 -2.4 -2.2
Type 2 Diabetes (T2D) (2018) 0.9 1.7 4.3 0.4 -0.6 -0.7 -0.2 1.8 1.3 2.1 -1.7 -0.6 1.0 -1.1 1.8 2.1 0.8
Lung FEV1/FVC ratio 0.5 2.3 5.6 -1.8 -2.2 0.9 -0.9 -1.9 -1.9 -0.3 -0.6 0.1 0.8 -1.8 -2.4 -1.5 -2.0
Lung FVC 0.5 2.7 8.0 2.4 2.3 -1.1 0.6 1.3 1.2 -0.8 2.2 -1.1 -0.2 2.8 1.9 0.9 1.6
Neuroticism 0.9 2.1 4.7 1.3 0.5 -2.1 -2.2 0.6 -0.8 0.9 -1.9 -0.7 -2.1 0.9 1.4 1.3 1.7
Chronotype (morning person) 0.5 1.2 5.0 -2.2 0.0 0.7 0.5 -0.9 -2.0 -1.6 0.2 -0.2 0.8 -0.7 -1.3 -0.8 -0.3
Hair Pigment 0.0 1.0 3.8 0.2 1.1 -0.8 0.2 0.7 0.6 -1.1 0.4 -1.9 0.6 -0.3 1.6 0.2 1.6
Tanning 0.1 1.3 4.4 -0.2 0.5 1.1 1.6 0.9 2.1 1.5 1.2 -1.3 1.6 0.2 0.2 0.3 -0.6
Hand grip strength (left) 1.6 4.1 14.0 -2.1 -0.6 2.5 1.4 -1.8 1.5 -1.1 1.0 -1.9 3.7 -1.6 -2.1 -2.6 -2.4
Number of treatments/medications taken 0.9 1.5 9.0 -1.5 -1.5 -1.0 -1.2 -0.5 -0.6 0.6 -3.0 -0.9 0.7 -1.8 0.1 -0.3 -0.2
Average weekly spirits intake 0.7 0.9 3.2 -1.0 -0.5 1.0 0.7 -0.3 1.3 1.3 0.0 -0.3 1.8 -1.2 -0.7 -0.3 -0.8
Sensitivity / hurt feelings 0.7 1.3 5.1 0.0 -1.3 -1.4 -2.3 -1.2 -0.6 -0.4 -1.9 -1.2 -0.6 -1.0 0.6 0.5 0.4
Frequency of depressed mood in last 2 weeks 0.2 0.2 1.0 0.7 -0.1 0.6 -0.3 0.5 0.3 1.0 0.2 -0.1 -0.3 0.4 0.4 0.6 0.5
Hearing difficulty/problems: Yes 0.5 0.8 2.7 -0.5 -0.8 0.1 0.6 -0.0 1.4 -1.0 -0.5 -1.6 1.3 -1.1 0.7 -0.5 -0.2
Relative age of first facial hair 1.5 3.2 8.5 1.5 -0.0 -2.1 -1.2 2.9 -0.3 1.1 -2.1 -0.8 -1.1 0.4 2.6 2.8 2.3
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.3 0.0 -0.5 0.0 -0.6 -0.0 0.0 0.6 -0.5 -0.3 -0.5 -0.2 0.4 -0.2 0.4
Ever used hormone-replacement therapy (HRT) 1.7 2.2 10.4 1.2 2.4 -0.4 0.2 2.2 1.5 3.2 -0.3 -0.2 0.7 1.2 0.9 1.8 0.3
Ever had hysterectomy (womb removed) 0.4 0.5 3.1 0.6 0.1 0.6 0.5 1.8 0.1 0.5 1.0 1.1 0.1 -0.1 0.5 -0.1 0.3
Systolic blood pressure, automated reading 0.3 1.0 2.9 -0.3 -0.5 -0.7 -1.2 0.5 0.8 1.7 -1.1 1.4 -0.5 0.2 1.3 1.3 0.8
Eye problems/disorders: Diabetes related eye disease 0.8 0.8 2.6 -0.5 -0.3 0.4 1.4 0.6 1.4 0.4 -0.4 -1.2 1.6 -1.6 0.3 -0.2 -0.5
Angina 1.5 2.0 5.8 1.3 -0.8 -1.6 -1.7 -0.2 1.5 -0.3 -0.8 -2.2 -0.8 -0.2 2.4 1.7 1.6
Medication for hormone replacement therapy 1.7 2.0 7.3 0.8 2.7 0.5 0.8 0.7 -0.6 2.5 0.8 1.6 -0.9 2.5 -1.0 -0.0 0.2
Vitamin and mineral supplements 1.4 1.9 4.4 -0.2 -1.1 -2.1 -1.8 0.2 -1.0 -0.1 -2.1 -1.5 -0.2 -1.5 1.6 1.9 1.3
Supplements: Zinc 0.9 1.0 2.7 -0.2 0.8 1.6 1.5 1.0 0.4 1.0 1.5 -0.6 0.9 0.4 -0.9 0.1 -1.5
Medication: Co-codamol 0.4 0.5 1.4 -0.0 -0.8 -0.4 -1.0 -0.5 0.8 -0.6 -1.2 -0.6 0.6 -1.1 0.5 -0.6 -0.1
Medication: Metformin 0.8 1.1 6.8 -0.5 -0.5 0.4 0.4 0.6 0.6 0.8 -0.0 -2.6 1.9 -1.1 0.7 1.3 -0.2
Diabetes (father) 0.2 0.2 0.6 0.7 0.6 -0.3 -0.2 -0.2 0.1 0.4 0.4 0.8 0.4 0.5 -0.4 0.4 -0.5
Diabetes (mother) 0.4 0.5 4.7 -0.3 -0.3 0.2 -0.5 -0.1 -0.4 0.1 -2.2 -0.1 0.6 -0.8 0.7 0.5 0.6
Severe depression (siblings) 0.4 0.5 1.7 0.6 0.5 0.1 1.1 0.2 0.6 0.6 0.0 1.3 -0.2 1.1 -0.6 -0.7 -0.3
Pack years adult smoking proportion 0.3 0.4 1.6 -0.1 -0.0 -0.5 -0.6 1.2 -1.3 0.1 -0.2 -0.6 0.2 -0.3 0.8 0.7 1.0
Impedance of leg (right) 1.0 4.8 15.7 3.3 0.7 -2.4 -2.1 0.9 -1.4 -0.4 1.3 1.8 -4.0 2.4 2.1 0.8 3.3
Leg fat-free mass (left) 2.3 12.4 53.9 -4.7 0.1 3.8 3.3 -0.8 3.4 0.4 -0.9 -3.3 7.3 -3.3 -3.0 -2.3 -4.9
Trunk fat percentage 0.8 3.4 13.6 -2.2 -0.8 0.1 -0.3 0.0 1.8 1.2 -3.2 -1.4 3.7 -2.8 -0.3 0.2 -1.7
Hand grip strength (right) 1.0 2.7 7.9 -1.1 0.1 1.8 1.3 -1.5 1.8 -1.3 1.5 -1.9 2.8 -0.7 -1.3 -2.5 -1.6
Townsend deprivation index at recruitment 2.8 3.9 7.6 2.8 0.1 -2.6 -1.8 2.0 -0.1 1.5 -1.6 0.8 -2.7 1.3 2.4 2.7 2.2
Current tobacco smoking 0.7 1.1 5.5 -0.4 0.3 -1.2 -0.7 0.8 -0.3 0.3 -1.0 -2.3 0.2 -0.6 1.3 1.7 0.9
Average weekly fortified wine intake 1.9 2.2 5.5 -2.3 -0.8 0.1 -0.4 -1.3 -1.7 -1.9 -1.1 -2.0 0.3 -2.0 -1.3 -2.1 -0.9
Maternal smoking around birth 1.2 1.8 8.1 0.1 -0.4 -1.5 -1.2 1.1 0.7 -0.1 -1.8 -2.9 0.7 -0.8 1.9 1.3 1.2
Fed-up feelings 0.6 1.1 2.8 1.5 -0.2 -1.1 -1.4 0.3 1.5 0.5 -0.8 -0.3 -0.3 0.3 1.7 1.6 1.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 3.3 0.4 -1.8 -0.4 -1.8 -0.5 -0.1 -0.6 -1.0 -0.5 -0.2 -0.5 0.9 0.6 0.8
Relative age voice broke 1.1 1.7 5.3 0.6 0.1 -1.9 -1.5 1.1 -0.5 0.6 -1.5 -0.4 -1.1 -0.0 1.9 1.7 2.3
Taking other prescription medications 0.2 0.4 1.9 -0.5 -0.3 0.2 -0.5 -0.1 0.5 -0.0 -0.6 -1.1 1.4 -0.6 0.3 0.4 -0.4
Age when periods started (menarche) 1.6 3.9 9.4 1.2 -0.0 -3.1 -2.9 0.5 -2.1 -0.8 -3.0 -0.5 -2.6 0.2 1.8 1.4 3.0
Bilateral oophorectomy (both ovaries removed) 3.1 3.6 11.4 2.0 2.4 -1.1 0.2 3.4 1.9 2.0 -0.1 0.8 -0.5 1.9 2.6 2.0 2.1
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.3 9.4 1.3 0.1 -3.1 -1.6 0.6 -0.0 1.6 -1.6 -0.9 -1.8 0.2 2.1 1.0 1.8
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 5.8 0.7 0.7 -0.7 0.6 1.0 2.3 -1.2 1.7 -2.4 2.0 0.3 1.4 -0.3 -0.2
Qualifications: CSEs or equivalent 1.4 1.9 5.4 0.2 0.4 0.6 2.0 1.2 2.3 -1.4 2.2 -1.6 2.3 -0.2 0.5 -0.6 -0.2
Serious illness, injury or assault to yourself 0.7 0.8 4.4 -0.5 -0.3 -0.2 -0.8 -1.4 -0.0 -2.1 -0.3 -0.8 0.6 -1.4 -0.0 -0.8 0.2
High blood pressure 0.6 1.7 5.8 -1.6 -1.8 0.1 0.1 0.7 1.6 0.5 -2.0 -0.5 2.4 -2.0 0.6 0.8 -0.6
Hayfever, allergic rhinitis or eczema 0.7 1.4 4.6 -1.1 1.2 1.6 2.1 -0.2 -0.6 0.8 1.4 1.2 -0.7 1.1 -1.8 -0.5 -0.9
Multivitamins +/- minerals 2.1 2.6 5.1 0.3 1.8 2.2 2.3 0.1 1.9 0.7 2.1 2.1 0.4 1.9 -1.4 -1.6 -1.5
Stomach or abdominal pain in last month 0.4 0.5 1.7 0.9 0.4 -0.2 -0.3 0.6 0.5 0.6 0.6 -1.1 -0.5 0.2 1.0 1.3 0.4
Supplements: Glucosamine 0.3 0.3 0.9 -0.1 -0.1 -0.4 -0.8 -0.7 -0.8 -0.4 -0.1 -0.9 0.8 -1.0 0.1 -0.4 -0.0
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 3.1 -1.2 -1.4 -0.3 -0.8 -1.5 -1.1 -0.3 -0.3 -0.4 0.2 -1.8 -0.3 -1.2 0.1
Medication: Atenolol 0.9 1.1 3.9 0.2 -1.4 0.5 0.3 1.2 1.1 2.0 -1.8 0.4 0.8 -0.8 0.9 1.2 0.2
Medication: Levothyroxine sodium 1.5 2.5 6.6 2.2 0.9 -1.8 -0.8 1.3 1.2 0.7 -0.3 0.8 -1.3 1.6 2.6 2.0 2.5
Sitting height 2.1 15.0 52.0 -4.6 0.6 4.8 3.4 -2.4 3.6 -2.0 1.6 -3.8 7.2 -2.7 -3.6 -4.0 -5.1
Chronic bronchitis/emphysema (father) 1.5 1.8 7.9 -0.3 -2.8 0.0 -2.3 -1.2 -1.4 0.4 -1.8 0.0 -0.4 -2.1 0.2 0.1 0.5
High blood pressure (mother) 1.3 1.8 11.1 0.4 1.3 0.7 1.4 1.4 0.7 1.4 0.6 3.3 -0.8 2.2 -0.3 0.2 -0.4
Body mass index (BMI) 1.1 4.9 17.6 -3.1 -1.1 0.3 -0.1 -0.5 1.9 0.6 -3.6 -2.4 4.2 -3.5 -0.5 0.1 -2.0
Impedance of leg (left) 1.0 4.8 17.6 3.0 0.3 -2.6 -2.6 0.6 -1.8 -0.2 0.7 1.7 -4.2 2.0 2.1 0.9 3.2
Leg predicted mass (left) 2.3 12.4 53.4 -4.6 0.1 3.8 3.3 -0.8 3.4 0.5 -0.9 -3.3 7.3 -3.3 -3.0 -2.4 -4.8
Trunk fat mass 1.5 6.6 29.2 -3.6 -1.1 1.1 0.4 -0.6 2.2 0.9 -3.0 -2.6 5.4 -3.8 -1.2 -0.8 -2.9
Waist circumference 1.3 4.7 16.7 -2.8 -1.4 -0.2 -0.6 -0.5 2.1 0.5 -3.5 -2.7 4.1 -3.6 0.1 0.5 -1.4
Number of incorrect matches in round 1.1 1.9 6.0 0.4 0.7 -1.8 -1.6 0.2 -0.1 -1.8 -1.4 -2.0 -0.6 -0.4 2.5 0.8 1.9
Past tobacco smoking 1.0 1.8 6.2 -0.8 -0.1 2.5 1.8 0.5 -0.9 -0.7 2.2 0.2 1.4 -0.2 -1.7 -1.0 -1.6
Alcohol usually taken with meals 1.6 2.5 7.5 -0.6 1.0 1.8 1.9 -1.5 0.1 0.3 2.7 1.2 -0.1 0.8 -2.6 -2.2 -2.0
Nervous feelings 0.4 0.8 2.5 0.1 -0.1 -1.2 -1.6 0.1 -1.3 0.3 -1.0 -0.5 -1.2 0.1 0.8 -0.4 1.5
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.1 6.4 2.5 1.0 -1.5 -1.2 1.6 0.4 0.1 -0.1 0.3 -1.8 2.1 1.7 1.0 1.9
Hearing difficulty/problems with background noise 1.1 1.7 9.7 1.5 1.1 0.2 1.1 1.3 3.1 -0.6 1.2 0.3 0.8 1.7 1.1 0.9 -0.5
Hair/balding pattern: Pattern 2 0.7 0.9 2.3 -1.2 -0.1 1.3 1.4 -0.0 -0.3 0.3 0.2 -0.1 1.3 -0.3 -1.5 -0.9 -1.3
Had menopause 0.6 0.8 2.1 -1.0 -1.4 -0.0 -1.4 -1.5 -0.5 -1.4 0.4 -0.4 0.2 -0.9 -0.5 -0.4 -0.6
Had other major operations 2.6 3.1 8.8 1.6 -0.2 -1.9 0.5 2.8 1.1 2.4 -0.5 0.3 -1.0 1.0 3.0 2.6 2.1
Forced vital capacity (FVC) 0.7 2.6 11.6 -0.4 1.3 1.5 2.3 0.7 2.1 -0.5 1.4 -2.4 3.4 0.2 -0.2 -1.3 -1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.2 5.7 1.6 0.1 -2.4 -0.8 1.5 0.9 2.4 -1.1 -0.4 -1.5 0.7 2.0 1.6 1.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 0.7 -0.7 -0.1 -0.8 -0.7 -0.5 -0.7 -0.3 -0.6 -0.5 -0.0 -0.0 0.3 -0.1 0.6
Qualifications: None of the above 2.4 5.2 16.2 2.1 -1.2 -2.8 -3.6 1.1 1.2 -0.8 -2.5 -1.4 0.1 -1.2 4.0 3.4 2.4
Financial difficulties in last 2 years 0.9 1.2 7.2 1.0 0.7 0.1 1.3 1.4 2.7 0.2 0.6 0.8 0.6 1.5 0.5 -0.2 0.2
Mouth/teeth dental problems 1.4 2.1 7.6 -1.2 0.9 1.3 2.8 -0.5 0.9 0.4 1.8 0.2 1.3 -0.0 -1.9 -2.2 -1.7
Heart attack 2.2 2.8 8.5 1.1 -1.7 -2.9 -2.3 0.6 1.0 -1.5 -1.1 -1.4 0.0 -1.4 2.9 1.6 1.4
Allergy 1.3 3.1 9.2 2.5 -0.6 -2.5 -2.0 1.9 1.1 0.8 -1.6 -0.0 -0.8 0.2 3.0 2.1 2.1
Pain all over the body in last month 1.9 2.0 6.3 1.3 -1.6 -1.5 -1.8 0.5 0.8 -0.7 -1.5 -0.1 -0.8 -0.6 2.5 2.1 1.8
Diabetes (self-reported) 0.7 1.1 2.9 0.3 -1.0 -0.9 0.0 1.1 1.3 1.3 -1.0 -0.9 1.2 -0.9 1.5 1.7 0.4
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 3.2 -0.3 -0.1 0.7 0.9 -0.7 -1.2 -0.4 1.7 1.8 -1.3 0.9 -1.5 -0.1 -0.5
Medication: Ramipril 0.5 0.7 2.0 0.5 -0.4 -1.1 -0.1 0.6 1.4 0.5 -1.0 -0.8 1.1 -0.5 1.4 0.7 0.3
Medication: Simvastatin 0.4 0.6 1.6 -0.7 -1.2 -0.8 -1.2 -1.2 -0.0 0.0 -1.3 0.7 0.1 -1.1 0.3 0.3 -0.0
Fluid intelligence score 0.6 1.1 5.1 -1.4 0.2 1.1 2.3 -1.1 0.9 0.6 0.6 -0.4 0.7 0.0 -1.1 -1.4 -1.1
Illnesses of siblings 0.8 1.1 7.9 0.9 0.7 0.6 0.5 -0.2 0.2 -0.5 2.8 1.1 -0.5 1.8 -0.7 -0.9 -0.1
Neuroticism score 1.1 2.3 6.3 1.4 -0.2 -2.3 -2.5 0.2 -0.5 0.4 -1.4 -1.3 -2.0 0.6 2.0 1.4 2.0
Weight 2.1 10.6 49.1 -4.5 -0.8 2.4 1.6 -0.9 3.1 0.6 -2.4 -3.5 7.0 -4.1 -2.2 -1.6 -4.1
Impedance of arm (right) 0.5 2.3 10.6 1.7 0.1 -1.2 -1.2 0.2 -2.5 0.2 0.7 2.2 -3.2 1.7 0.2 0.1 1.4
Arm fat percentage (right) 1.2 4.6 14.2 -3.3 -1.3 -0.2 -0.4 -0.6 1.0 0.8 -3.7 -2.0 3.8 -3.6 -0.7 -0.3 -2.0
Trunk fat-free mass 2.3 13.4 53.1 -5.0 0.1 4.0 3.3 -1.3 2.9 -0.1 0.0 -3.8 7.3 -3.5 -3.5 -3.2 -4.9
Hip circumference 1.6 6.7 24.3 -4.3 -1.0 1.3 0.2 -1.8 1.6 0.5 -2.7 -2.7 4.9 -3.6 -1.9 -1.2 -3.2
Time employed in main current job 1.3 1.5 5.2 -1.2 -1.6 -0.2 -0.7 -1.9 -0.6 -2.3 -0.6 -0.2 0.4 -1.6 -1.0 -1.4 -0.9
Alcohol intake versus 10 years previously 2.0 3.0 7.6 2.2 1.7 -2.0 -1.6 1.8 -0.7 1.0 -1.1 0.9 -2.0 1.7 2.0 2.8 1.5
Father’s age at death 0.5 0.6 1.7 0.7 0.8 -0.5 -0.4 0.5 -0.1 1.2 0.6 0.9 -1.3 1.0 0.7 0.6 1.0
Worrier / anxious feelings 0.3 0.6 2.3 0.8 -0.7 -0.8 -1.0 -0.1 -0.4 0.4 -1.1 -0.2 -1.5 0.4 0.6 0.3 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.8 1.3 -1.3 0.4 -0.4 0.7 0.8 -0.3 -0.3 0.5 -0.8 0.7 0.3 0.4 -0.1
Falls in the last year 0.4 0.6 2.0 0.3 -0.7 -0.3 -0.6 1.2 -0.1 0.4 -0.4 -1.4 -0.2 -0.8 1.2 1.0 1.0
Hair/balding pattern: Pattern 3 0.2 0.3 1.3 -0.2 0.3 0.8 -0.1 -0.8 0.2 -0.3 0.7 -0.2 1.1 0.1 -0.5 -0.6 -0.6
Number of live births 3.3 4.7 8.7 2.9 2.2 -1.8 -1.0 2.5 2.8 2.1 -0.0 1.1 0.1 2.5 3.0 2.8 2.3
Forced expiratory volume in 1-second (FEV1) 0.5 1.8 8.8 -0.3 0.8 1.2 1.6 0.5 1.9 -0.6 0.9 -1.7 3.0 0.1 -0.5 -1.5 -1.2
Pulse rate 2.5 4.3 11.6 3.4 -0.5 -2.1 -1.7 1.7 0.6 -0.4 1.3 0.4 -2.2 2.3 3.2 2.3 3.1
Happiness 4.1 4.9 12.5 -3.5 -0.3 1.8 1.6 -2.2 -0.9 -1.9 1.2 -3.0 3.0 -2.3 -2.1 -2.9 -2.0
Noisy workplace 3.2 3.9 10.4 -1.8 -1.7 -1.7 -2.5 -1.5 -1.5 -0.9 -3.1 -3.2 1.4 -3.0 1.4 -0.5 1.2
Qualifications: A levels/AS levels or equivalent 0.7 1.5 4.5 -0.4 -0.4 1.6 2.0 -0.6 -0.1 0.8 1.3 2.1 -0.6 1.2 -1.6 -0.2 -1.2
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 3.7 0.2 1.2 -0.0 -0.2 -0.3 -1.9 -0.3 1.4 0.1 -1.1 0.8 -0.1 -0.4 0.7
Mouth/teeth dental problems: Dentures 0.3 0.5 2.6 -0.7 -0.3 0.2 -0.9 -0.2 -0.9 -0.3 -1.6 -0.1 -0.1 -0.7 -0.3 0.7 -0.4
Asthma 3.0 5.9 16.4 -3.6 -0.0 1.9 0.1 -4.0 -2.0 -3.0 0.3 -1.0 0.8 -1.3 -3.7 -3.4 -2.9
Medication: Ibuprofen (e.g. Nurofen) 3.2 4.1 9.2 -3.0 -2.2 -0.7 -1.9 -2.1 -2.2 -0.7 -2.9 -2.4 0.9 -2.9 -1.5 -1.1 -1.2
Medication: Cholesterol lowering 0.7 1.1 5.6 -1.0 -2.4 0.6 -0.1 -1.5 0.2 -1.1 -0.4 1.1 0.8 -1.0 -0.7 -0.6 -1.1
Depression (self-reported) 1.6 1.9 4.8 2.0 0.3 -0.7 -0.3 1.9 0.8 2.1 -0.4 0.6 -1.3 1.7 1.3 2.2 1.1
Medication: Lansoprazole 0.7 0.8 5.3 1.3 -1.0 -0.3 -0.5 0.5 2.3 0.1 -0.1 -0.1 0.5 -0.1 1.4 0.8 0.1
Prospective memory result 0.7 0.9 4.5 0.4 -2.1 0.0 -1.0 0.4 -1.4 -0.8 0.0 -0.4 -1.0 -0.8 1.0 -0.1 1.3
Lung cancer (father) 2.0 2.4 6.8 -2.6 -1.1 0.4 -0.7 -2.0 -0.2 -2.0 -2.2 -0.8 1.2 -2.1 -1.1 -1.3 -1.5
Illnesses of mother 1.8 2.3 7.1 -2.0 0.0 0.3 0.1 -2.3 -1.7 -1.4 0.3 -2.7 0.7 -1.7 -1.8 -1.6 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 8.1 0.4 0.7 1.0 1.8 1.1 1.6 -0.3 2.1 -2.2 2.9 0.2 -0.1 -1.2 -0.9
Pulse wave Arterial Stiffness index 0.8 1.0 4.9 -0.0 -0.7 -0.4 -0.0 0.3 1.4 0.8 -1.1 -0.6 -0.2 -0.6 2.2 1.3 1.4
Impedance of arm (left) 0.6 2.6 9.8 2.2 0.4 -0.7 -0.6 0.4 -1.7 0.6 1.1 2.8 -3.1 2.4 0.3 0.4 1.4
Arm fat mass (right) 1.7 6.9 27.7 -4.0 -0.9 1.1 0.7 -0.6 1.9 0.8 -3.1 -2.9 5.3 -4.0 -1.3 -0.9 -2.9
Trunk predicted mass 2.3 13.2 52.7 -4.9 0.2 4.0 3.3 -1.3 3.0 0.1 0.1 -3.6 7.3 -3.4 -3.5 -3.1 -5.0
Standing height 1.4 13.5 51.3 -3.8 0.6 5.2 4.0 -0.8 3.1 0.2 2.1 -2.8 7.2 -2.0 -3.8 -3.8 -5.0
Length of working week for main job 3.0 3.3 9.4 -2.2 -0.6 2.8 1.9 -1.6 0.4 -0.9 1.1 0.7 2.0 -0.7 -3.0 -1.5 -3.1
Exposure to tobacco smoke at home 3.0 3.4 11.1 -0.3 -0.9 -3.0 -3.3 -1.6 -0.6 -0.9 -2.3 -1.7 -1.1 -1.3 2.3 1.8 1.6
Breastfed as a baby 0.9 1.1 3.2 -1.3 -0.9 0.6 0.1 -1.4 -1.4 -0.7 0.9 0.1 1.2 -1.2 -1.8 -0.7 -1.2
Tense / ‘highly strung’ 1.8 3.0 8.4 2.1 -0.2 -2.7 -1.8 2.3 -0.3 0.2 -0.6 -1.2 -1.4 1.0 2.9 0.9 2.8
Seen doctor (GP) for nerves, anxiety, tension or depression 1.5 2.2 6.3 1.4 -0.7 -0.8 -0.7 1.9 0.4 2.5 -2.3 1.5 -1.7 1.2 1.1 1.7 1.3
Hair/balding pattern: Pattern 4 0.2 0.6 2.3 -0.2 -0.2 0.5 -0.1 -1.2 0.8 -1.5 0.2 -0.2 0.4 0.1 -1.2 -0.5 -1.1
Birth weight of first child 1.4 2.5 8.0 -1.4 -1.0 2.3 0.6 -1.0 0.3 -0.1 -0.4 -1.3 2.0 -1.6 -2.7 -1.1 -2.8
Peak expiratory flow (PEF) 0.7 1.6 4.5 -1.5 -0.3 1.6 0.8 -1.2 -0.0 0.1 -0.2 -0.9 1.9 -0.9 -2.1 -2.0 -1.5
Pulse wave reflection index 0.5 0.7 2.7 -1.4 -0.4 0.7 1.1 -0.4 1.3 0.4 -1.6 0.3 0.3 -0.6 0.2 0.2 -0.5
Ever highly irritable/argumentative for 2 days 0.7 0.9 3.0 0.6 -0.5 -1.3 -1.4 0.6 -0.3 -0.2 -0.4 -0.6 -0.5 -0.3 1.7 1.1 1.6
Loud music exposure frequency 0.8 0.9 3.6 -0.7 -0.9 -0.2 -1.4 -1.1 -0.6 -1.9 -0.3 -1.7 0.5 -0.9 0.5 0.3 0.6
Qualifications: O levels/GCSEs or equivalent 2.0 3.2 11.2 -0.4 2.4 1.8 3.3 0.6 1.4 2.0 2.5 1.9 0.2 1.7 -1.6 -1.2 -1.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 3.3 1.4 0.4 -1.0 -0.3 0.9 0.4 0.5 0.1 -0.2 0.0 0.9 1.8 1.5 1.4
Blood clot in the leg (DVT) 0.9 1.2 3.5 -0.7 0.7 0.8 1.6 0.5 0.2 -0.7 1.8 -1.0 1.9 -0.2 -1.1 -0.7 -1.5
Medication: Paracetamol 2.0 3.3 12.7 -0.9 -0.7 -2.2 -2.8 -0.8 -1.6 -0.3 -3.0 -3.6 0.3 -2.2 1.1 1.1 1.1
Headache pain in last month 0.4 0.7 3.6 0.2 0.4 0.7 -0.1 0.8 -1.9 0.7 0.4 0.3 -1.6 1.0 -1.0 -0.3 -0.4
Medication for cholesterol, blood pressure or diabetes 1.6 2.7 10.7 1.7 3.3 -0.6 0.0 1.4 -1.2 1.3 1.8 0.1 -2.1 2.4 0.6 1.6 1.5
Glaucoma (self-reported) 0.9 1.1 3.1 0.4 1.1 1.2 1.8 1.7 0.4 -0.2 1.7 0.5 1.0 0.8 -0.4 -0.9 -0.6
Gout (self-reported) 0.3 0.4 1.0 -0.8 -0.7 -0.1 -0.8 -0.8 -1.0 0.1 -0.1 0.2 0.6 -0.9 -0.1 0.7 -0.1
Hypothyroidism/myxoedema (self-reported) 0.9 1.8 5.9 1.4 1.0 -0.9 -0.5 1.5 1.8 0.9 -1.2 -0.2 -0.5 0.7 2.4 1.8 1.9
Medication: Amlodipine 1.1 1.6 4.8 0.2 -1.1 -1.9 -1.6 -0.5 1.8 -0.3 -2.2 0.7 0.2 -1.1 1.7 0.1 1.2
Medication: Ventolin 100micrograms inhaler 2.8 3.6 11.8 -3.4 0.2 0.5 0.0 -2.5 -2.4 -2.4 -0.0 -2.0 0.8 -2.1 -2.3 -1.7 -2.0
Birth weight 1.5 3.2 9.1 -2.0 -0.6 2.8 1.7 -1.4 0.5 -1.0 1.0 -1.6 3.0 -1.9 -1.7 -1.7 -2.0
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.4 0.9 -0.8 -0.2 -1.0 1.6 -0.0 -0.1 -0.8 -0.2 -0.7 0.4 1.1 1.1 0.6
High blood pressure (siblings) 0.7 1.0 8.2 -0.3 -1.1 0.8 0.5 0.6 0.3 1.0 -2.9 1.2 -0.4 -0.1 0.2 0.9 0.3
Forced vital capacity (FVC), Best measure 0.8 2.8 9.8 0.3 1.4 1.3 2.5 1.2 1.9 -0.2 2.7 -2.5 3.1 0.5 -0.0 -1.0 -1.0
Body fat percentage 0.9 3.4 13.2 -2.2 -1.0 -0.5 -0.9 -0.3 1.3 1.0 -3.6 -1.6 3.3 -3.0 -0.0 0.3 -1.4
Leg fat percentage (right) 0.8 3.1 11.9 -1.9 -0.9 -1.7 -1.9 -0.2 0.9 0.2 -3.5 -2.1 2.3 -2.8 1.1 0.6 -0.1
Arm fat-free mass (right) 2.1 10.9 50.0 -3.9 0.4 3.5 3.1 -0.4 3.9 0.6 -0.1 -3.4 7.1 -2.9 -2.4 -2.1 -4.3
Exposure to tobacco smoke outside home 1.6 2.2 7.7 -0.4 -0.4 -2.6 -2.8 -0.3 -0.6 0.3 -2.5 -1.3 -0.9 -1.1 1.4 1.5 1.2
Comparative body size at age 10 0.8 2.2 6.2 -1.6 -0.7 1.9 1.6 -1.3 0.9 -1.0 -0.3 -0.6 2.5 -1.6 -1.8 -0.7 -2.2
Number of full brothers 2.3 2.9 9.2 0.6 -1.8 -2.1 -3.0 -0.9 -0.9 -1.6 -2.1 -1.0 -1.9 -1.4 1.8 1.6 1.6
Worry too long after embarrassment 0.3 0.5 1.7 -0.3 -0.9 -0.2 -1.3 -1.0 -0.7 -1.0 -1.1 -0.0 -0.8 -0.2 -0.1 -0.3 -0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.7 0.8 -0.4 0.6 0.3 0.3 -0.2 1.3 0.2 1.1 -0.7 1.2 -0.5 0.3 -0.5
Wheeze or whistling in the chest in last year 1.1 1.9 4.3 -2.1 0.3 1.4 0.1 -1.3 -1.1 -1.9 0.2 -1.8 1.1 -1.3 -1.8 -1.7 -1.4
Number of children fathered 0.2 0.3 1.1 -0.2 -1.0 0.3 0.3 0.5 -0.1 -0.2 0.1 -0.4 0.6 -0.8 0.6 -0.1 0.6
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 2.1 0.1 -1.5 0.1 -0.2 -0.4 -0.1 0.7 -0.3 0.9 0.7 -0.5 -0.8 -0.9 -0.6
Age at first live birth 5.0 8.8 24.9 -3.5 0.8 4.2 3.5 -2.4 -1.8 -1.4 0.9 0.4 2.4 -1.5 -5.0 -4.2 -4.3
Pulse wave peak to peak time 1.0 1.2 5.9 -0.1 1.0 0.6 0.3 -0.3 -1.0 -0.7 1.4 0.3 0.7 0.6 -2.4 -1.6 -1.7
Health satisfaction 1.3 1.6 8.8 -1.0 -1.4 1.5 0.8 -0.5 0.5 -0.5 -0.6 -1.4 3.0 -1.6 -0.6 -0.6 -1.5
Shortness of breath walking on level ground 0.7 0.8 2.2 -0.6 -0.8 0.2 -1.1 -1.4 -0.1 -1.2 -1.0 -1.2 1.1 -1.5 0.1 -0.0 -0.7
Qualifications: College or University degree 1.4 4.5 13.0 -1.5 -0.6 2.7 1.5 -2.4 -1.9 -1.0 0.9 2.4 -1.8 0.5 -3.6 -3.4 -2.2
Eye problems/disorders: None of the above 2.0 2.4 6.2 2.5 0.5 -1.4 -1.2 -0.8 -0.0 -0.8 1.5 1.7 -2.4 2.3 1.2 0.6 2.0
Mouth/teeth dental problems: Loose teeth 0.9 1.1 4.2 0.6 0.2 -1.0 -2.0 0.8 0.1 0.6 -2.1 -0.3 -0.5 -0.3 1.2 1.1 1.4
Emphysema/chronic bronchitis 0.2 0.2 1.0 0.2 0.2 0.9 0.2 -0.2 -0.8 -1.0 -0.0 0.4 0.2 0.1 -0.4 -0.2 -0.3
Medication for pain relief, constipation, heartburn 2.6 4.4 14.7 1.6 2.6 2.5 2.8 0.7 1.3 0.5 3.8 3.0 -1.0 3.1 -0.8 -0.9 -0.5
Neck or shoulder pain in last month 0.9 1.2 5.0 -0.1 -0.7 -1.1 -2.2 -0.8 -1.7 -0.1 -1.9 -0.7 -1.0 -0.7 0.7 -0.0 1.0
Medication: Blood pressure 1.6 2.9 12.7 -1.5 -3.6 0.6 -0.5 -1.5 1.0 -1.6 -2.0 -1.0 2.0 -2.6 -0.3 -1.4 -1.1
Angina (self-reported) 1.5 1.9 5.7 1.4 -0.8 -1.5 -1.5 0.0 1.7 0.0 -0.6 -2.1 -0.8 -0.1 2.4 1.9 1.6
Migraine (self-reported) 0.3 0.3 1.0 0.0 0.1 0.0 -0.8 -0.8 -0.2 -0.8 -0.5 -0.4 -0.3 0.1 -1.0 -0.6 -0.9
Medication: Ibuprofen 1.3 1.6 3.6 -1.9 -1.6 -0.5 -0.9 -1.3 -1.1 -0.0 -1.9 -1.3 0.9 -1.9 -0.9 -0.8 -0.8
Medication: Allopurinol 0.3 0.3 1.4 0.1 -0.8 1.2 0.1 -0.2 -0.2 0.2 0.6 0.9 0.6 -0.3 -0.8 0.2 -0.6
Medication: Omeprazole 0.9 1.1 4.3 0.9 0.1 -0.9 -0.4 1.2 1.6 0.1 -1.3 0.6 -0.1 0.5 2.1 1.6 1.0
Medication: Seretide 50 evohaler 0.5 0.6 2.8 -0.9 -0.6 0.9 0.1 -0.7 -1.7 -0.2 -0.3 0.2 0.5 -1.1 -1.1 -0.6 -0.5
Mean time to correctly identify matches 0.5 1.0 3.0 -1.6 0.4 1.4 0.4 -0.7 -1.0 1.4 -0.9 0.4 -0.7 -0.0 -1.7 0.2 -1.1
Heart disease (mother) 0.9 1.1 4.0 1.6 -0.9 -1.1 -1.0 1.3 1.5 0.4 -0.3 0.3 -0.2 0.6 1.3 2.0 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 4.2 -0.2 -2.0 -0.9 -1.4 -1.2 -1.0 -0.5 -1.9 1.5 -1.5 -0.8 0.1 -0.5 0.6
Whole body fat mass 1.6 6.6 27.5 -3.7 -1.1 0.8 0.2 -0.8 2.1 0.8 -3.2 -2.7 5.2 -3.9 -1.1 -0.7 -2.9
Leg fat mass (right) 1.5 5.7 22.6 -3.5 -1.1 0.2 -0.4 -0.9 1.9 0.4 -3.2 -3.2 4.8 -3.9 -0.4 -0.7 -2.0
Arm predicted mass (right) 2.1 10.8 48.9 -3.9 0.4 3.5 3.3 -0.4 3.8 0.5 0.0 -3.2 7.0 -2.7 -2.6 -2.1 -4.4
Pulse rate, automated reading 2.9 9.3 22.9 3.9 -0.0 -2.6 -2.4 2.5 -0.6 1.6 0.5 0.1 -4.7 3.1 4.4 4.3 4.8
Alcohol intake frequency. 0.5 1.2 4.7 -1.2 -0.1 -1.4 -1.8 -0.5 -2.2 -0.9 -1.4 -1.0 0.1 -1.3 -0.1 -0.3 -0.1
Comparative height size at age 10 1.9 10.3 38.1 -3.4 1.2 4.0 3.9 -0.8 3.0 0.8 2.2 -1.9 6.2 -2.0 -3.2 -3.1 -4.3
Number of full sisters 1.8 2.1 7.0 1.6 -1.0 -0.8 -1.0 1.2 1.8 1.0 -1.3 0.2 0.0 0.5 2.5 2.6 2.0
Suffer from ‘nerves’ 1.6 2.6 6.1 1.6 0.1 -1.9 -1.3 2.1 -0.3 2.0 -1.3 -0.4 -1.9 0.9 2.0 1.8 2.5
Overall health rating 1.0 2.1 7.1 -1.0 -1.8 -0.3 -1.8 -0.7 -0.5 -1.0 -2.0 -2.7 1.4 -2.4 0.6 0.6 0.0
Chest pain or discomfort 0.4 0.5 1.9 0.1 -1.3 -0.2 -0.7 0.2 0.1 -0.2 -1.2 -1.0 0.7 -1.4 0.3 0.3 0.0
Had major operations 0.1 0.1 0.8 -0.1 -0.4 0.1 -0.0 -0.4 0.3 -0.2 0.4 -0.4 -0.0 -0.1 0.1 -0.9 0.0
Age at last live birth 1.6 2.3 7.8 -1.2 1.1 2.8 2.3 -0.6 -0.9 -0.7 0.6 0.7 1.3 0.0 -2.4 -1.7 -1.7
Family relationship satisfaction 0.8 0.9 3.9 0.4 0.5 -0.4 0.7 0.5 0.3 -1.6 1.7 -2.0 1.1 -0.0 0.5 -0.8 0.4
Leg pain on walking 0.7 0.9 3.1 -0.2 -0.1 -1.8 -1.4 0.6 -0.5 -0.2 -1.2 -0.9 0.3 -1.0 1.6 0.1 1.2
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 4.3 0.5 0.5 -0.3 2.1 2.0 1.6 1.2 1.2 0.0 1.2 0.6 0.8 0.9 0.2
Commuting to job workplace: Car/motor vehicle 2.9 3.3 9.9 -1.6 -3.0 -0.4 -1.5 -2.3 -1.2 -1.2 -1.9 -2.4 1.1 -3.2 0.0 -1.9 0.0
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.8 0.2 -1.3 -0.5 -1.3 -0.0 -0.2 0.1 -0.7 -0.5 -0.6 -0.5 0.9 0.7 0.7
Medication: Aspirin 1.4 1.9 5.7 -0.1 -2.3 -1.7 -0.9 0.4 0.9 0.3 -2.4 -1.0 0.9 -1.8 1.7 1.2 1.0
Supplements: Vitamin C 0.8 1.0 4.2 0.1 0.1 1.8 0.8 -0.3 0.1 -0.4 2.0 1.3 0.4 1.0 -1.1 -0.7 -0.8
Knee pain experienced in last month 0.9 1.4 4.2 0.3 0.1 -1.5 -1.2 1.3 -0.3 0.4 -2.0 -1.5 -0.3 -0.2 1.7 2.0 0.5
Hypertension (Self-reported) 0.5 1.4 4.4 -1.0 -1.6 -0.1 0.2 0.9 1.8 0.6 -1.8 -0.3 2.1 -1.6 0.9 0.9 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.3 -0.5 -1.0 -0.3 -0.7 -0.9 1.4 -1.5 -0.4 -0.1 0.5 -0.9 0.5 0.0 -0.1
Illnesses of father: Heart disease 1.6 2.2 7.5 0.8 1.4 -0.0 2.4 2.5 1.2 2.7 -0.3 0.2 0.7 0.7 0.2 2.5 -0.5
Illnesses of siblings: Diabetes 1.1 1.3 4.3 1.5 2.1 -0.2 0.8 1.6 1.9 0.7 0.3 0.3 -0.0 1.1 1.3 0.9 0.4
Smoking status: Previous 0.8 1.2 3.8 0.7 -0.2 -2.0 -1.8 -0.9 0.5 0.4 -1.9 0.5 -1.2 0.1 1.0 0.3 1.3
Forced expiratory volume in 1-second (FEV1), predicted 2.0 4.1 11.0 -3.3 -0.3 1.6 2.0 -1.3 0.9 -1.1 0.5 -1.8 3.3 -2.0 -2.2 -2.6 -2.4
Whole body fat-free mass 2.4 13.6 55.7 -4.9 0.2 4.0 3.4 -1.1 3.3 0.3 -0.4 -3.7 7.5 -3.5 -3.4 -2.9 -5.1
Leg fat-free mass (right) 2.3 12.1 50.7 -4.6 0.0 3.8 3.2 -0.9 3.2 0.5 -0.8 -3.3 7.1 -3.3 -3.1 -2.3 -5.0
Arm fat percentage (left) 1.1 4.2 13.5 -3.1 -1.2 -0.0 -0.2 -0.7 1.1 1.0 -3.7 -1.6 3.6 -3.4 -0.8 -0.3 -2.0
Average weekly red wine intake 0.8 1.2 4.7 -0.1 0.3 1.1 2.0 -0.2 1.4 0.3 2.2 1.4 0.2 0.8 -1.0 -0.8 -0.7
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.9 0.3 1.4 -0.3 -0.1 1.0 0.9 0.1 -0.7 -0.0 0.4 0.3 1.2 0.6 0.9
Mood swings 0.6 1.0 2.2 0.8 1.4 -0.5 -0.1 1.1 0.8 1.5 0.3 -1.0 -0.5 1.2 1.5 1.2 1.0
Loneliness, isolation 0.8 1.1 2.8 1.2 -1.0 -0.3 -1.7 -0.4 -0.0 -1.3 0.1 -0.1 -1.6 0.9 1.3 1.2 1.1
Long-standing illness, disability or infirmity 0.1 0.2 0.8 0.1 -0.7 -0.1 -0.7 0.1 0.5 0.2 -0.9 -0.4 0.3 -0.2 0.6 0.4 -0.0
Ever had bowel cancer screening 0.3 0.3 1.0 -0.1 -0.9 -0.2 -1.0 -0.3 0.2 -0.3 0.3 -0.1 0.5 -0.9 0.7 -0.6 0.2
Diabetes diagnosed by doctor 0.7 1.1 3.3 0.8 -0.6 -0.3 0.5 1.2 1.8 1.6 -0.2 -0.7 1.4 -0.3 1.4 1.7 0.3
Ever had stillbirth, spontaneous miscarriage or termination 2.9 3.1 8.5 2.1 1.3 -0.8 1.1 2.2 2.2 1.9 -0.2 1.1 -1.0 2.1 2.1 2.9 1.5
Friendships satisfaction 1.2 1.5 4.6 -0.8 0.3 0.4 0.7 -1.1 -0.4 -2.0 1.3 -2.1 1.4 -0.3 -0.9 -2.2 -1.2
Qualifications: nursing, teaching 3.4 5.2 18.0 1.2 2.2 2.4 3.0 0.6 0.9 3.0 2.0 4.2 -1.0 3.5 -2.0 -0.5 -1.6
Commuting to job workplace: Walk 1.1 1.2 5.3 1.0 1.6 -0.9 0.7 2.3 1.4 1.0 0.1 0.3 0.7 0.5 1.1 1.2 0.4
Eye problems/disorders: Cataract 1.8 2.0 5.7 -1.3 -0.1 0.9 1.8 2.2 0.9 1.8 -1.0 -1.0 2.4 -1.3 -0.4 1.5 -1.4
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 5.6 1.5 -0.4 -1.6 -2.4 -0.1 -0.1 -1.1 -0.2 0.2 -1.6 0.9 1.5 0.5 1.7
Medication for cholesterol 0.9 1.3 4.8 -0.5 -1.7 0.9 -0.1 -2.0 -0.4 -2.2 1.2 -0.5 -0.2 -0.6 -0.8 -1.6 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.7 8.4 -2.1 0.1 0.7 -0.4 -1.1 0.7 -0.9 -0.3 -1.1 2.9 -1.7 -1.2 -0.1 -1.6
Back pain experienced in last month 1.1 1.5 5.5 1.7 0.5 -1.5 -1.1 1.4 0.6 -0.0 0.0 -1.6 0.3 0.3 2.3 1.6 1.4
Mineral and other dietary supplements 0.4 0.5 1.7 -0.8 0.8 -0.5 0.2 0.4 -0.4 0.9 -1.3 0.1 -0.4 0.1 0.4 1.3 0.5
Breast cancer (self-reported) 1.5 1.8 6.2 1.3 0.2 -1.2 -1.6 0.8 -1.4 0.2 -1.4 0.8 -2.5 0.8 1.2 2.0 1.6
Asthma (self-reported) 2.8 5.6 16.6 -3.5 -0.2 1.5 -0.2 -4.1 -2.3 -2.9 0.1 -0.9 0.7 -1.4 -3.5 -3.3 -2.6
Osteoporosis (self-reported) 2.4 3.0 7.4 -1.8 -0.6 1.9 0.3 -2.7 -0.8 -2.6 2.2 0.4 0.4 -0.3 -2.4 -2.3 -1.8
Osteoarthritis (self-reported) 2.9 3.8 8.6 2.9 -0.7 -2.1 -1.8 1.0 0.9 0.0 -0.3 2.1 -2.3 2.4 2.5 2.8 2.3
Medication: Aspirin 1.4 1.8 5.8 -0.2 -2.4 -1.6 -0.7 0.4 0.8 0.0 -2.0 -1.4 1.3 -1.9 1.6 0.8 0.9
Medication: Gliclazide 1.0 1.1 4.3 -0.6 -0.1 0.6 1.2 0.7 1.8 -0.4 -0.6 -1.4 2.1 -0.8 0.5 1.1 -0.7
Illnesses of father: None of the above (group 1) 1.5 1.8 6.4 1.9 1.9 -0.0 0.0 1.0 0.6 -1.1 2.0 1.3 -1.4 2.5 0.9 0.2 1.2
Smoking status: Current 0.6 1.0 3.7 -0.1 0.3 -1.1 -0.3 1.0 -0.3 0.6 -0.9 -1.7 -0.2 -0.2 1.4 1.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.7 1.3 -1.0 0.4 -0.0 1.1 0.4 0.7 0.8 0.0 0.6 0.0 0.6 -0.1 0.6
Whole body water mass 2.4 14.0 57.5 -4.9 0.2 4.1 3.5 -1.0 3.3 0.3 -0.2 -3.7 7.6 -3.5 -3.4 -2.9 -5.1
Leg predicted mass (right) 2.3 12.0 50.4 -4.6 0.0 3.8 3.2 -0.9 3.2 0.5 -0.8 -3.3 7.1 -3.3 -3.1 -2.4 -4.9
Arm fat mass (left) 1.6 6.7 28.2 -3.8 -1.0 1.4 0.9 -0.6 2.2 1.1 -2.9 -2.5 5.3 -3.8 -1.4 -0.8 -3.0
Number of self-reported non-cancer illnesses 0.5 0.9 5.0 -0.7 -2.2 -0.6 -0.6 -1.1 0.3 -0.7 -1.6 0.0 0.3 -1.2 0.1 0.4 -0.8
Average weekly champagne plus white wine intake 1.0 1.4 5.4 -2.0 0.3 0.8 -0.3 -1.2 -1.2 0.7 -1.4 -0.3 -0.0 -1.1 -2.3 -0.3 -1.6
Miserableness 0.8 1.4 5.8 0.3 -0.4 -1.1 -1.4 0.4 1.1 0.5 -1.8 -2.4 0.8 -1.0 1.6 1.1 0.9
Guilty feelings 0.7 1.1 4.1 0.3 1.0 -1.1 -1.1 -0.9 -1.7 0.2 0.9 1.3 -2.0 1.2 -0.4 0.1 0.4
Wears glasses or contact lenses 0.3 0.4 1.2 0.4 -0.9 -0.1 -0.2 0.4 0.2 -0.2 -1.0 1.1 -0.7 0.1 0.6 0.6 0.8
Ever taken oral contraceptive pill 4.0 4.5 12.9 3.6 1.9 -1.5 -0.5 1.6 0.5 1.8 1.6 0.6 -2.5 3.6 1.9 2.3 2.6
Hearing aid user 0.3 0.3 1.3 -0.8 0.0 -0.7 -0.5 0.1 -0.4 -0.4 0.1 -1.1 0.7 -0.5 0.5 0.8 0.2
Mother’s age at death 1.6 2.0 6.0 -1.6 1.1 2.0 1.6 -1.2 -0.7 0.2 1.2 0.7 1.2 -0.1 -2.4 -1.7 -2.0
Financial situation satisfaction 0.7 0.8 3.3 -0.5 -0.6 0.9 0.5 0.2 0.7 -1.6 0.9 -1.8 1.6 -0.8 -0.1 -0.1 -0.3
Tinnitus: Yes, now most or all of the time 3.1 3.6 13.1 0.4 -0.8 -1.6 -3.3 -1.1 -3.6 -0.5 -2.1 0.5 -2.8 -0.5 0.8 -0.1 3.0
Commuting to job workplace: Public transport 0.8 0.9 3.6 -0.3 1.1 1.8 1.9 0.6 0.9 1.1 1.3 0.1 -0.4 0.5 -0.2 -0.1 0.1
Eye problems/disorders: Glaucoma 0.8 0.9 2.6 -0.8 1.4 1.3 1.6 0.9 0.3 -0.1 1.6 -0.2 1.3 0.1 -0.5 -0.8 -0.4
Medication: Blood pressure 1.4 2.7 8.1 0.3 0.3 -1.9 -0.0 2.5 1.4 2.9 -2.6 0.5 0.4 -0.3 2.1 2.1 1.1
Pain type(s) experienced in last month: Hip pain 0.4 0.5 2.0 -0.3 -0.6 0.7 0.0 0.5 0.5 -1.1 -0.3 -0.5 1.4 -0.5 -0.3 0.0 -0.9
Supplements: Fish oil (including cod liver oil) 0.7 0.9 3.0 1.2 -0.4 1.0 0.2 -0.3 1.4 -1.1 1.7 -0.2 0.8 -0.1 -0.3 -1.5 -0.7
High cholesterol (Self-reported) 0.5 0.8 4.0 -1.2 -1.0 -1.2 -0.2 -1.3 -0.6 -2.0 -0.6 -0.4 0.1 -1.1 0.6 -0.2 0.2
Medication: Bendroflumethiazide 0.9 1.3 4.9 -0.3 -0.8 -0.4 -0.2 1.4 1.5 1.5 -2.2 1.0 1.0 -0.9 1.0 1.3 0.8
Medication: Paracetamol 1.7 2.6 9.8 -1.0 -0.9 -1.3 -1.9 -0.4 -1.5 1.1 -2.9 -3.1 0.2 -2.1 0.6 1.3 0.8
Medication: Lisinopril 0.9 1.1 5.6 -0.6 -2.4 0.3 0.0 -0.6 0.1 0.1 -1.1 -0.4 1.6 -1.8 -0.7 -0.9 -1.0
Medication: Atorvastatin 0.5 0.6 2.5 0.1 -0.2 -1.4 -0.4 0.3 0.4 -1.0 -0.9 -1.6 0.5 -0.6 0.8 0.2 0.2
Illnesses of father: High blood pressure 1.1 1.3 5.8 -0.8 -2.4 -0.7 -1.4 -0.8 -1.2 -0.3 -2.0 -0.9 0.0 -1.4 -0.2 -0.7 0.2
Alcohol drinker status: Never 0.8 0.9 2.6 -0.6 -1.2 0.3 -0.1 -1.3 -1.1 -0.8 0.1 1.6 -0.1 -0.7 -1.1 -1.6 -0.7
Ever smoked 1.2 2.0 8.2 0.4 0.4 -2.9 -2.2 -0.4 0.3 0.2 -2.4 -0.4 -1.3 0.2 1.8 0.9 1.8
Basal metabolic rate 2.4 13.1 57.2 -4.8 0.0 3.6 3.1 -0.9 3.4 0.4 -0.9 -3.7 7.6 -3.7 -3.0 -2.6 -4.9
Leg fat percentage (left) 1.0 3.6 14.6 -2.1 -1.0 -1.8 -2.1 -0.3 0.8 0.3 -3.8 -2.1 2.4 -3.1 1.1 0.7 -0.3
Arm fat-free mass (left) 2.0 10.2 47.6 -4.0 0.1 3.1 2.6 -0.5 3.5 0.4 -0.5 -3.4 6.9 -3.3 -2.3 -2.2 -4.1
Number of operations (self-reported) 1.3 1.9 5.2 1.6 0.7 -0.2 1.3 2.3 2.3 2.2 0.4 1.0 0.3 1.1 1.4 1.2 0.7
Average weekly beer plus cider intake 1.6 2.2 8.2 1.2 0.1 -1.6 -1.6 1.1 -0.3 0.9 -1.2 0.1 -0.5 0.6 2.4 2.9 2.5
Irritability 0.8 1.3 3.5 0.9 1.1 -1.8 -1.9 0.3 -0.9 0.1 -0.6 -1.5 -0.6 0.3 1.2 1.1 1.7
Risk taking 0.2 0.4 1.5 -0.3 0.2 0.3 0.0 -0.9 0.5 -0.7 -0.5 -0.5 0.7 -0.8 -0.4 -1.2 -0.3
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.3 -0.7 -0.7 0.4 -0.3 -0.5 0.9 -0.3 -1.0 -0.6 0.5 -1.2 0.9 0.8 0.5
Fractured/broken bones in last 5 years 0.3 0.4 1.4 -0.1 0.3 -0.5 -0.6 -1.0 -1.2 -0.7 -0.2 0.3 -0.9 0.8 -0.3 0.1 -0.0
Age started oral contraceptive pill 0.4 0.5 1.3 1.1 -0.4 -0.1 -0.4 0.4 0.7 -0.4 1.0 0.9 -0.9 1.1 0.6 0.6 0.4
Diastolic blood pressure, automated reading 0.6 1.8 4.9 -0.6 -0.3 -0.9 -0.5 2.1 0.7 1.7 -2.0 -0.9 0.0 -0.0 2.2 2.2 1.2
Ever depressed for a whole week 1.3 1.6 5.3 1.4 -0.3 -1.6 -1.5 1.5 -0.1 -1.0 0.0 -1.0 -0.9 0.9 2.3 1.2 1.8
Unable to work because of sickness or disability 1.3 1.7 6.8 2.6 0.5 -0.4 -0.0 1.1 2.0 -0.2 1.4 1.0 -0.6 1.9 1.4 0.9 1.0
Commuting to job workplace: Cycle 0.6 0.7 2.4 -0.9 -0.4 0.8 0.7 -0.2 -0.5 -0.2 0.0 1.2 -0.7 -0.1 -1.5 -1.6 -0.7
Myopia 0.3 0.5 2.0 0.5 -1.4 0.2 -0.2 -0.5 1.3 -0.6 -0.3 -0.0 0.2 -0.2 1.0 -0.1 1.0
Vascular/heart problems diagnosed by doctor 0.8 2.3 6.0 1.6 2.3 0.7 0.5 -0.3 -1.6 0.2 2.4 1.1 -2.3 2.4 -1.4 -0.9 0.1
Cholesterol lowering medication 0.4 0.6 2.7 -0.7 -0.2 -1.6 -1.1 -0.2 -0.2 0.6 -0.8 -0.7 -0.1 -0.8 0.9 1.0 0.8
Medication: Omeprazole (e.g. Zanprol) 1.5 1.9 5.1 1.3 -0.1 -1.5 -1.1 1.3 0.9 0.4 -1.7 1.1 -1.1 0.6 2.2 2.3 1.5
Pain experienced in last month 1.4 2.4 6.5 -0.8 0.9 2.2 2.6 -1.0 1.4 -0.9 2.2 1.2 1.0 0.3 -1.8 -1.9 -1.4
Supplements: Calcium 1.1 1.2 4.3 0.2 1.0 1.5 0.6 -0.7 -0.8 -1.2 2.1 1.2 -0.4 1.2 -1.2 -0.9 -1.0
Basal cell carcinoma (self-reported) 1.1 1.4 4.2 0.9 0.1 -1.0 0.7 0.8 1.6 -0.9 1.0 -1.7 1.2 0.1 2.1 0.5 1.6
Heart attack/myocardial infarction (self-reported) 1.9 2.5 8.2 1.2 -1.5 -2.9 -2.0 0.6 1.1 -1.2 -0.8 -1.3 -0.0 -1.1 2.8 1.6 1.4
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 3.2 -0.6 0.7 0.7 1.7 0.7 0.2 -0.7 1.8 -1.3 1.8 -0.2 -0.7 -0.7 -1.1
Heart disease (siblings) 0.8 1.0 3.9 1.0 -0.3 -1.2 -0.8 1.5 -0.2 0.6 -0.2 -0.4 -0.9 0.0 1.5 2.0 0.9
Alcohol drinker status: Previous 1.6 1.8 6.4 -1.5 -0.6 0.5 0.3 -1.5 -2.5 0.7 -1.1 0.7 -0.9 -0.6 -2.4 -1.5 -1.8
Pack years of smoking 0.4 0.6 1.6 0.3 -0.5 -0.6 -1.0 1.1 -1.2 0.4 -0.4 -0.3 -0.0 -0.3 1.0 1.0 1.3
Impedance of whole body 0.8 4.2 15.5 3.1 0.4 -1.6 -1.5 0.9 -1.7 0.2 1.1 2.8 -3.9 2.6 1.4 0.9 2.6
Leg fat mass (left) 1.5 5.9 22.6 -3.6 -1.1 0.1 -0.5 -0.9 1.9 0.4 -3.4 -3.1 4.8 -3.9 -0.3 -0.6 -2.0
Arm predicted mass (left) 2.0 10.4 45.7 -4.2 0.4 3.3 2.7 -0.4 3.1 0.5 -0.4 -3.5 6.8 -3.3 -2.6 -2.1 -4.4