[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr17:41,946,180-43,913,030

Best TWAS P=6.18e-13 · Best GWAS P=4.97e-13 conditioned to 0.634

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	GTEx	Thyroid	ACBD4	0.20	0.16	enet	23	0.15	1.2e-11	-5.8	-7.2	6.2e-13	0.51	0.89	0.11	TRUE
6	GTEx	Breast Mammary Tissue	KANSL1	0.31	0.00	enet	9	0.11	2.6e-06	4.4	-6.1	8.8e-10	0.08	0.00	0.04	TRUE
3	GTEx	Artery Coronary	NMT1	0.13	0.06	enet	7	0.11	1.5e-04	4.1	-5.3	1.4e-07	0.53	0.09	0.47	TRUE
1	GTEx	Adipose Subcutaneous	ACBD4	0.10	0.06	enet	8	0.06	1.8e-05	-5.8	-6.6	5.2e-11	0.52	0.53	0.34	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	HEXIM1	0.05	0.05	blup	47	0.04	8.5e-05	-7.2	6.4	1.3e-10	-0.84	0.00	1.00	FALSE
12	GTEx	Nerve Tibial	ACBD4	0.21	0.10	lasso	5	0.11	4.2e-08	-5.3	-6.4	1.5e-10	0.47	0.88	0.11	FALSE
13	GTEx	Skin Sun Exposed Lower leg	ACBD4	0.06	0.05	lasso	4	0.02	3.8e-03	4.9	-6.4	1.6e-10	0.33	0.19	0.08	FALSE
5	GTEx	Artery Tibial	ACBD4	0.10	0.09	lasso	2	0.08	4.8e-07	-6.0	-6.0	2.2e-09	0.58	0.73	0.21	FALSE
10	GTEx	Esophagus Muscularis	KANSL1	0.41	0.11	enet	8	0.15	1.3e-09	4.4	-5.4	6.9e-08	0.05	0.00	0.91	FALSE
7	GTEx	Breast Mammary Tissue (Female)	FZD2	0.10	0.08	lasso	2	0.05	1.1e-02	5.1	5.4	7.0e-08	-0.07	0.04	0.15	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACBD4	0.08	0.04	enet	9	0.04	6.9e-06	-5.8	-5.3	9.6e-08	0.50	0.85	0.11	FALSE
2	GTEx	Artery Aorta	DCAKD	0.22	0.16	enet	26	0.19	1.1e-10	-2.7	5.3	1.0e-07	-0.46	0.93	0.06	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	PLCD3	0.24	0.16	lasso	5	0.20	2.8e-19	4.8	5.3	1.2e-07	-0.15	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NMT1	0.23	0.08	blup	82	0.12	1.1e-05	3.0	-5.3	1.4e-07	0.55	0.05	0.90	FALSE
9	GTEx	Esophagus Mucosa	ACBD4	0.14	0.10	lasso	4	0.10	4.5e-07	4.8	-5.2	1.7e-07	0.13	0.60	0.08	FALSE
4	GTEx	Artery Tibial	KANSL1	0.31	0.07	lasso	6	0.07	1.7e-06	4.4	-5.2	1.8e-07	-0.01	0.00	0.91	FALSE
11	GTEx	Lung	KANSL1	0.34	0.07	enet	30	0.11	1.7e-08	4.4	-5.2	1.8e-07	0.00	0.00	0.83	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	NMT1	0.24	0.21	lasso	4	0.22	2.8e-08	3.1	-5.2	2.2e-07	0.54	0.20	0.79	FALSE
16	METSIM	Adipose	C17orf104	0.05	0.02	bslmm	404	0.04	4.2e-06	4.9	-5.2	2.3e-07	0.11	0.91	0.00	FALSE
14	GTEx	Stomach	DCAKD	0.29	0.17	enet	25	0.20	9.4e-10	-2.7	5.2	2.6e-07	-0.48	0.62	0.38	FALSE
17	YFS	Blood	NMT1	0.02	0.01	lasso	6	0.01	5.0e-03	5.0	-5.1	2.7e-07	0.37	0.26	0.09	FALSE